Results 1 to 10 of about 100,610 (328)

Regional Targeted Subcutaneous Injection of Botulinum Neurotoxin Type A in Refractory Chronic Migraine: A Randomized, Double-Blind, Placebo-Controlled Study

Toxins, 2023
In this randomized, double-blind, placebo-controlled study, we evaluated the efficacy of an individualized technique of subcutaneous injection of botulinum toxin type A (BoNT-A) targeted (SjBoT) to the occipital or trigeminal skin area in non-responder ...
Francesco Bono, Maria Rosaria Mazza, Giuseppe Magro, Giorgio Spano, Giovanni Idone, Vincenzo Laterza, Denise Tedeschi, Francesco Pucci, Antonio Gambardella, Alessia Sarica   +9 more
doaj   +1 more source

Effect of vitamin D and other indicators of phosphorus-calcium metabolism on cognitive functions and quality of life in patients with Parkinson's disease

Неврология, нейропсихиатрия, психосоматика, 2022
Parkinson’s disease (PD) is a multifactorial neurodegenerative disease. Consequently, there has been growing interest in identifying early preclinical disease symptoms and searching for their laboratory markers in recent decades.Objective: to studythe ...
D. A. Novotnyy, N. G. Zhukova, L. P. Shperling, V. A. Stolyarova, I. A. Zhukova, A. E. Agasheva, S. V. Shtaimets, O. A. Druzhinina, I. V. Shirokikh   +8 more
doaj   +1 more source

Rehabilitation approaches in cervical dystonia

Неврология, нейропсихиатрия, психосоматика, 2021
Cervical dystonia (CD) is a form of focal muscular dystonia. The pathophysiology of CD includes central and peripheral sensorimotor mechanisms that lead to a pathological posture, imbalance, gait disturbances, and pain.
Z. A. Zalyalova, E. R. Iusupova
doaj   +1 more source

Botulinum toxin preparations: areas for improvement and issues of standardisation

Биопрепараты: Профилактика, диагностика, лечение, 2023
Scientific relevance. Botulinum toxin preparations are a good example of using a deadly toxin as a unique therapeutic agent. However, there are many unresolved issues related to biotechnology, biological activity, interchangeability, and standardisation ...
M. V. Savkina, M. A. Krivykh, L. V. Sayapina, Yu. I. Obukhov, V. P. Bondarev   +4 more
doaj   +1 more source

Release of vasopressin from isolated permeabilized neurosecretory nerve terminals is blocked by the light chain of botulinum A toxin [PDF]

, 1990
The intracellular action on exocytosis of botulinim A toxin and constituent chains was studied using permeabilized isolated nerve endings from the rat neural lobe. The release of the neuropeptide vasopressin was measured by radioimmunoassay.
Ahnert-Hilger, G., Dayanithi, G., Gratzl, Manfred, Nordmann, J. J., Weller, U.   +4 more
core   +6 more sources

Wide range applications of botulinum toxin in medicine - literature review

Journal of Education, Health and Sport, 2023
Introduction and purpose : Botulinum toxin is one of the most dangerous natural toxins. Botulinum toxin poisoning causes botulism. Botulism is a set of systemic symptoms resulting from flaccid muscle paralysis.
Aleksandra Serwik-Trandasir, Agata Kania, Malwina Gonet, Karolina Miszczyk, Karolina Włodarczyk-Cybulska, Patrycja Maj, Natalia Sergiel, Piotr Mozer, Jakub Maternia, Michal Lazar   +9 more
doaj   +1 more source

Cervical dystonia: non-motor aspects

Неврология, нейропсихиатрия, психосоматика, 2020
Cervical dystonia (CD) is manifested by violent, often painful movements of the neck muscles with the abnormal head and/or neck postures being formed. Disease progression leads to disability of patients.
O. A. Druzhinina, N. G. Zhukova, L. P. Shperling, D. A. Novotnyi   +3 more
doaj   +1 more source

Benign essential blepharospasm: epidemiology, clinical manifestations, pathophysiology, botulinum toxin therapy

Неврология, нейропсихиатрия, психосоматика, 2021
Blepharospasm (BPS) is a variant of focal dystonia manifested by involuntary eyelid spasms with eye closure and/or increased spontaneous blinking. Along with motor symptoms, this condition is characterized by sensory, affective, and cognitive disorders ...
Z. A. Zalyalova
doaj   +1 more source

Isolation and typing of Clostridium botulinum from milk powder of an enterprise associated with a case of infant botulism

Zhongguo shipin weisheng zazhi, 2023
ObjectiveThe aim of this study was to detect botulinum toxin and Clostridium botulinum （C.botulinum） in 30 batches of infant formula milk powder obtained from an enterprise and to analyze the whole genome of the strain of C.
LUO Haipeng, QU Hongren, DING Bo, REN Xiu, ZHAO Linna, BAI Jichao, WANG Yaping, LIN Lan, CUI Shenghui   +8 more
doaj   +1 more source

Prolonged Antipruritic Effect of Botulinum Toxin Type A on Cowhage-induced Itch: A Randomized, Single-blind, Placebo-controlled Trial

Acta Dermato-Venereologica, 2023
Botulinum toxin type A (Botox®) is thought to have antipruritic effects through inhibition of pruritic factors, including acetylcholine, substance P, and glutamate. The aim of this randomized, single-blind, placebo-controlled trial was to test the effect
Leigh A. Nattkemper, Ashley Vander Does, Carolyn M. Stull, Michael J. Lavery, Rodrigo Valdes-Rodriguez, Marlene McGregory, Yiong Huak Chan, Gil Yosipovitch   +7 more
doaj   +1 more source