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Treatment of chronic pain associated with nocturnal bruxism with botulinum toxin. A prospective and randomized clinical study [PDF]

open access: yesJournal of Clinical and Experimental Dentistry, 2017
To evaluate the role of botulinum toxin type A (BTX-A) in the treatment of pain associated with nocturnal bruxism. Fifty subjects reporting nocturnal bruxism were recruited for a randomized clinical trial. Twenty five bruxers were injected with botulinum
Al Wayli, Hessa
core   +2 more sources

Botulinum toxin A for the Treatment of Overactive Bladder

open access: yesToxins, 2016
The standard treatment for overactive bladder starts with patient education and behavior therapies, followed by antimuscarinic agents. For patients with urgency urinary incontinence refractory to antimuscarinic therapy, currently both American Urological
Po-Fan Hsieh   +4 more
doaj   +2 more sources

Regional Targeted Subcutaneous Injection of Botulinum Neurotoxin Type A in Refractory Chronic Migraine: A Randomized, Double-Blind, Placebo-Controlled Study

open access: yesToxins, 2023
In this randomized, double-blind, placebo-controlled study, we evaluated the efficacy of an individualized technique of subcutaneous injection of botulinum toxin type A (BoNT-A) targeted (SjBoT) to the occipital or trigeminal skin area in non-responder ...
Francesco Bono   +9 more
doaj   +1 more source

Botulinum Toxin: An Update on Pharmacology and Newer Products in Development

open access: yesToxins, 2021
Since its introduction as a treatment for strabismus, botulinum toxin (BoNT) has had a phenomenal journey and is now recommended as first-line treatment for focal dystonia, despite short-term clinical benefits and the risks of adverse effects.
S. Choudhury   +3 more
semanticscholar   +1 more source

Effect of vitamin D and other indicators of phosphorus-calcium metabolism on cognitive functions and quality of life in patients with Parkinson's disease

open access: yesНеврология, нейропсихиатрия, психосоматика, 2022
Parkinson’s disease (PD) is a multifactorial neurodegenerative disease. Consequently, there has been growing interest in identifying early preclinical disease symptoms and searching for their laboratory markers in recent decades.Objective: to studythe ...
D. A. Novotnyy   +8 more
doaj   +1 more source

Botulinum Toxin in Movement Disorders: An Update

open access: yesToxins, 2021
Since its initial approval in 1989 by the US Food and Drug Administration for the treatment of blepharospasm and other facial spasms, botulinum toxin (BoNT) has evolved into a therapeutic modality for a variety of neurological and non-neurological ...
Charenya Anandan, J. Jankovic
semanticscholar   +1 more source

Overview of DaxibotulinumtoxinA for Injection: A Novel Formulation of Botulinum Toxin Type A

open access: yesDrugs, 2021
Botulinum toxin type A (BoNTA) products are widely used for therapeutic and aesthetic indications, but there is a need for longer-lasting treatments that maintain symptom relief between injections and reduce the frequency of re-treatment ...
N. Solish   +5 more
semanticscholar   +1 more source

Rehabilitation approaches in cervical dystonia

open access: yesНеврология, нейропсихиатрия, психосоматика, 2021
Cervical dystonia (CD) is a form of focal muscular dystonia. The pathophysiology of CD includes central and peripheral sensorimotor mechanisms that lead to a pathological posture, imbalance, gait disturbances, and pain.
Z. A. Zalyalova, E. R. Iusupova
doaj   +1 more source

Benign essential blepharospasm: epidemiology, clinical manifestations, pathophysiology, botulinum toxin therapy

open access: yesНеврология, нейропсихиатрия, психосоматика, 2021
Blepharospasm (BPS) is a variant of focal dystonia manifested by involuntary eyelid spasms with eye closure and/or increased spontaneous blinking. Along with motor symptoms, this condition is characterized by sensory, affective, and cognitive disorders ...
Z. A. Zalyalova
doaj   +1 more source

Botulinum toxin preparations: areas for improvement and issues of standardisation

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2023
Scientific relevance. Botulinum toxin preparations are a good example of using a deadly toxin as a unique therapeutic agent. However, there are many unresolved issues related to biotechnology, biological activity, interchangeability, and standardisation ...
M. V. Savkina   +4 more
doaj   +1 more source

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