Results 31 to 40 of about 100,610 (328)

Botulinum Toxin Type A With Oral Baclofen Versus Oral Tizanidine: A Nonrandomized Pilot Comparison in Patients With Cerebral Palsy and Spastic Equinus Foot Deformity [PDF]

, 2008
The objective Of this Study was to compare the effectiveness of baclofen versus tizanidine as adjuvant treatment of botulinum toxin type A botulinum toxin type A in the management of children with spasticity. Thirty children with gastroenemius spasticity
Awan, Safia, Dai, Alper I., Wasay, Mohammad   +2 more
core   +2 more sources

Botulinum Toxin for Pain [PDF]

Drugs in R & D, 2008
Botulinum toxin (BTX) injection is being increasingly used 'off label' in the management of chronic pain. Data support the hypothesis of a direct analgesic effect of BTX, different to that exerted on muscle. Although the pain-reducing effect of BTX is mainly due to its ability to block acetylcholine release at the synapse, other effects on the nervous ...
Valeria Tugnoli, Roberto Casale
openaire   +3 more sources

Development of a technique for DNA detection and identification of toxigenic strains of Clostridium botulinum types A, B, E by the Real-Time PCR method

Вестник войск РХБ защиты, 2023
Botulism is dangerous toxic infection caused by a toxin produced by the bacterium Clostridium botulinum. The mortality rate from botulism can reach 70% of all cases of illness in case of untimely initiation of treatment.
D. S. Yanov, A. V. Kuznetsovskiy, M. I. Dubrovin, A. V. Mironin, N. V. Onuchina, A. V. Filippov   +5 more
doaj   +1 more source

Arrangement of the Clostridium baratii F7 toxin gene cluster with identification of a σ factor that recognizes the botulinum toxin gene cluster promoters.

PLoS ONE, 2014
Botulinum neurotoxin (BoNT) is the most poisonous substances known and its eight toxin types (A to H) are distinguished by the inability of polyclonal antibodies that neutralize one toxin type to neutralize any of the other seven toxin types.
Nir Dover, Jason R Barash, Julianne N Burke, Karen K Hill, John C Detter, Stephen S Arnon   +5 more
doaj   +1 more source

Molecular Aspects of Secretory Granule Exocytosis by Neurons and Endocrine Cells [PDF]

, 1994
Neuronal communication and endocrine signaling are fundamental for integrating the function of tissues and cells in the body. Hormones released by endocrine cells are transported to the target cells through the circulation.
Ahnert-Hilger G., Ahnert-Hilger G., Bader M. F., Baumert M., Bittner M. A., Bittner M. A., Bittner M. A., Blasi J., Elferink L. A., Fischer G., Geppert M., Halpern J. L., Hess S. D., Jahn R., MANFRED GRATZL, Marqueze-Pouey B., McMahon H. T., Schiavo G., Schiavo G., Schiavo G., Schmidle T., Shirataki H., Shoji-Kasai Y., Stecher B., Thomas L., Trimble W. S., Walch-Solimena C., Wright J. F., Yoshida A.   +28 more
core   +1 more source

Tetanus: Pathophysiology, Treatment, and the Possibility of Using Botulinum Toxin against Tetanus-Induced Rigidity and Spasms

Toxins, 2013
Tetanus toxin, the product of Clostridium tetani, is the cause of tetanus symptoms. Tetanus toxin is taken up into terminals of lower motor neurons and transported axonally to the spinal cord and/or brainstem. Here the toxin moves trans-synaptically into
Bjørnar Hassel
doaj   +1 more source

Diagnostic nerve block in prediction of outcome of botulinum toxin treatment for spastic equinovarus foot after stroke: A retrospective observational study

Journal of Rehabilitation Medicine, 2020
Objective: To evaluate the role of diagnostic nerve block in predicting the outcome of subsequent botulinum toxin type A treatment for spastic equinovarus foot due to chronic stroke. Design: Retrospective observational study.
Alessandro Picelli, Elisa Battistuzzi, Mirko Filippetti, Angela Modenese, Marialuisa Gandolfi, Daniele Munari, Nicola Smania   +6 more
doaj   +1 more source

Exploring the functional domain and the target of the tetanus toxin light chain in neurohypophysial terminals [PDF]

, 1994
The tetanus toxin light chain blocks calcium induced vasopressin release from neurohypophysial nerve terminals. Here we show that histidine residue 233 within the putative zinc binding motif of the tetanus toxin light chain is essential for the ...
Binz, T., Dayanithi, G., Gratzl, Manfred, Höhne-Zell, B., Niemann, H., Stecher, B., Weller, U., Yamasaki, S.   +7 more
core   +1 more source

Service-based survey of dystonia in Munich [PDF]

, 2002
We performed a service-based epidemiological study of dystonia in Munich, Germany. Due to favourable referral and treatment patterns in the Munich area, we could provide confident data from dystonia patients seeking botulinum toxin treatment.
Ben-Shlomo, Y., Ceballos-Baumann, Andres, Conrad, B., Gasser, T., Kamm, C., Konkiewitz, E. C., Trender-Gerhard, I., Warner, T.   +7 more
core   +1 more source

Botulinum toxin A for the Treatment of Overactive Bladder

Toxins, 2016
The standard treatment for overactive bladder starts with patient education and behavior therapies, followed by antimuscarinic agents. For patients with urgency urinary incontinence refractory to antimuscarinic therapy, currently both American Urological
Po-Fan Hsieh, Hung-Chieh Chiu, Kuan-Chieh Chen, Chao-Hsiang Chang, Eric Chieh-Lung Chou   +4 more
doaj   +1 more source