Results 1 to 10 of about 43,287 (326)

Botulinum toxin

Indian Journal of Dermatology, 2010
Botulinum toxin, one of the most poisonous biological substances known, is a neurotoxin produced by the bacterium Clostridium botulinum. C. botulinum elaborates eight antigenically distinguishable exotoxins (A, B, C 1 , C 2 , D, E, F and G).
Nigam P, Nigam Anjana
doaj   +3 more sources

Diffusion of Botulinum Toxins

Tremor and Other Hyperkinetic Movements, 2012
Background: It is generally agreed that diffusion of botulinum toxin occurs, but the extent of the spread and its clinical importance are disputed.
Matthew A. Brodsky, David M. Swope, David Grimes   +2 more
doaj   +5 more sources

Gut mucin fucosylation dictates the entry of botulinum toxin complexes [PDF]

Nature Communications
Botulinum toxins (BoNTs) produced by Clostridium botulinum are the most potent known bacterial toxins. The BoNT complex from serotype B-Okra (LPTC/BOkra) exerts at least 80-fold higher oral toxicity in mice compared with that from serotype A1 (L-PTC/A62A)
Sho Amatsu, Takuhiro Matsumura, Chiyono Morimoto, Sunanda Keisham, Yoshiyuki Goto, Tomoko Kohda, Jun Hirabayashi, Kengo Kitadokoro, Takane Katayama, Hiroshi Kiyono, Hiroaki Tateno, Masahiko Zuka, Yukako Fujinaga   +12 more
doaj   +2 more sources

Therapeutic Use of Botulinum Neurotoxins in Dermatology: Systematic Review

Toxins, 2021
Botulinum toxin is a superfamily of neurotoxins produced by the bacterium Clostridium Botulinum with well-established efficacy and safety profile in focal idiopathic hyperhidrosis.
Emanuela Martina, Federico Diotallevi, Giulia Radi, Anna Campanati, Annamaria Offidani   +4 more
doaj   +1 more source

Electrical Stimulation of Injected Muscles to Boost Botulinum Toxin Effect on Spasticity: Rationale, Systematic Review and State of the Art

Toxins, 2021
Botulinum toxin type A (BoNT-A) represents a first-line treatment for spasticity, a common disabling consequence of many neurological diseases. Electrical stimulation of motor nerve endings has been reported to boost the effect of BoNT-A. To date, a wide
Alessandro Picelli, Mirko Filippetti, Giorgio Sandrini, Cristina Tassorelli, Roberto De Icco, Nicola Smania, Stefano Tamburin   +6 more
doaj   +1 more source

rAAV expressing recombinant neutralizing antibody for the botulinum neurotoxin type A prophylaxis

Frontiers in Microbiology, 2022
Botulinum neurotoxin (BoNT) is one of the most dangerous bacterial toxins and a potential biological weapon component. BoNT mechanism of pathological action is based on inhibiting the release of neurotransmitters from nerve endings.
Artem A. Derkaev, Ekaterina I. Ryabova, Ilias B. Esmagambetov, Dmitry V. Shcheblyakov, Svetlana A. Godakova, Irina D. Vinogradova, Anatoly N. Noskov, Denis Y. Logunov, Boris S. Naroditsky, Alexander L. Gintsburg   +9 more
doaj   +1 more source

Introduction to the Toxins Special Issue on Botulinum Neurotoxins in the Nervous System: Future Challenges for Novel Indications

Toxins, 2020
Botulinum toxins (BoNTs) are a true wonder of nature [...]
Siro Luvisetto
doaj   +1 more source

Botulinum Neurotoxin Serotypes Detected by Electrochemical Impedance Spectroscopy

Toxins, 2015
Botulinum neurotoxin is one of the deadliest biological toxins known to mankind and is able to cause the debilitating disease botulism. The rapid detection of the different serotypes of botulinum neurotoxin is essential for both diagnosis of botulism and
Alison C. Savage, Nicholas Buckley, Jennifer Halliwell, Christopher Gwenin   +3 more
doaj   +1 more source

Botulinum Neurotoxins (BoNTs) and Their Biological, Pharmacological, and Toxicological Issues: A Scoping Review

Applied Sciences, 2021
Botulinum toxins or neurotoxins (BoNTs) are the most potent neurotoxins known, and are currently extensively studied, not only for their potential lethality, but also for their possible therapeutic and cosmetic uses.
Massimo Corsalini, Francesco Inchingolo, Gianna Dipalma, Angelika Elzbieta Wegierska, Ioannis Alexandros Charitos, Maria Assunta Potenza, Antonio Scarano, Felice Lorusso, Alessio Danilo Inchingolo, Monica Montagnani, Luigi Santacroce   +10 more
doaj   +1 more source

A survey of traditional Iranian food products for contamination with toxigenic Clostridium botulinum

Journal of Infection and Public Health, 2009
Summary: This study aimed to determine the rate of Clostridium botulinum contamination in some traditional Iranian food products (cheese, kashk and salted fish) and evaluate the efficacy of the mouse bioassay method in detection of C. botulinum toxins in
H.R. Tavakoli, M. Aghazadeh Meshgi, N. Jonaidi Jafari, M. Izadi, R. Ranjbar, A.A. Imani Fooladi   +5 more
doaj   +1 more source