Results 21 to 30 of about 12,537 (253)
The 9th International RASopathies Symposium
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT The RASopathies are a group of congenital disorders with overlapping clinical manifestations that are caused by pathogenic germline or early somatic variants that result in the hyperactivation of the RAS/mitogen‐activated protein kinase (MAPK) signaling pathway.
Pau Castel +41 more
wiley +1 more source
Tables of toxicity of botulinum and tetanus neurotoxins [PDF]
, 2019 Tetanus and botulinum neurotoxins are the most poisonous substances known, so much so as to be considered for a possible terrorist use. At the same time, botulinum neurotoxin type A1 is successfully used to treat a variety of human syndromes ...
CESARE MONTECUCCO, ORNELLA ROSSETTO
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BOTULINUM TOXIN IN OPHTHALMOLOGY [PDF]
Australian and New Zealand Journal of Ophthalmology, 1988 AbstractAlan B. Scott selected, researched and developed Type A Botulinum toxin for clinical use in ophthalmology. This unique drug has proved invaluable for treatment of a number of conditions which are difficult to treat in ophthalmology and in a variety of other disciplines.
D, Dunlop, G, Pittar, C, Dunlop
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British Journal of Clinical Pharmacology, EarlyView.Carbamazepine is licensed in the United Kingdom for the treatment of epilepsy, bipolar disorder and trigeminal neuralgia. The related compounds oxcarbazepine and eslicarbazepine are licensed for the treatment of epilepsy. These drugs can cause immune‐mediated hypersensitivity reactions, which typically affect the skin, and can be of variable severity ...
Lucy Galloway +24 more
wiley +1 more source
BMEMat, EarlyView.This review comprehensively summarizes emerging biomaterial‐based strategies and underlying mechanisms for modulating endogenous tendon stem/progenitor cells (TSPCs). It offers the most recent insights into TSPC physiology and potential applications of tissue engineering and regenerative medicine in tendons.
Zeyu Zhu +9 more
wiley +1 more source
Uso da Toxina Botulínica em Odontologia [PDF]
, 2013 TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.As Neurotoxinas Botulínicas são produzidas pela bactéria anaeróbia Clostridium botulinum e são consideradas as toxinas mais potentes conhecidas e sua ...
Gonçalves, Bruna Miroski
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Harnessing the Membrane Translocation Properties of AB Toxins for Therapeutic Applications
, 2021 Over the last few decades, proteins and peptides have become increasingly more common as FDA-approved drugs, despite their inefficient delivery due to their inability to cross the plasma membrane.
Oksana A. Sergeeva +2 more
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Clinical Anatomy, EarlyView.ABSTRACT The orbicularis oculi muscle (OOc) is strongly associated with facial aging as its contraction causes the formation of crow's feet. Botulinum neurotoxin (BoNT) injection is a representative treatment targeting muscle. The aim of this study was to demonstrate the anatomical relationship between the OOc and the zygomaticus complex muscles, and ...
Jiong‐Zhen Piao +3 more
wiley +1 more source
Botulinum toxin-A for the treatment of overactive bladder: UK contributions
, 2013 Background: Botulinum toxin-A (BoNT/A) is now established second-line management for refractory overactivebladder (OAB) and recognised in many incontinence guidelines and pathways.
Fowler, CJ +13 more
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Updated ERNICA guidelines for the management of rectosigmoid Hirschsprung's disease 2025
Journal of Pediatric Gastroenterology and Nutrition, EarlyView.Abstract Objectives To revise the 2018 European Reference Network for rare Inherited and Congenital Digestive and Gastrointestinal Anomalies (ERNICA) clinical guideline for the management of rectosigmoid Hirschsprung's disease (HSCR) based on new evidence and evolving clinical priorities, ensuring continued relevance, trustworthiness, and consistency ...
Daniel Rossi +35 more
wiley +1 more source