Results 1 to 10 of about 16,430 (149)

A large travel-associated outbreak of iatrogenic botulism in four European countries following intragastric botulinum neurotoxin injections for weight reduction, Türkiye, February to March 2023

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2023
In March 2023, 34 associated cases of iatrogenic botulism were detected in Germany (30 cases), Switzerland (two cases), Austria (one case), and France (one case).
M. B. Dorner, H. Wilking, Martin Skiba, Laura Wilk, Maximilian Steinberg, S. Worbs, Sabahat Çeken, S. Kaygusuz, S. Simon, F. Becher, A. Mikołajewska, C. Kornschober, Timo Bütler, Nathalie Jourdan-Da-Silva, M. an der Heiden, L. Schaade, K. Stark, B. Dorner, C. Frank   +18 more
semanticscholar   +1 more source

Clinical Guidelines for Diagnosis and Treatment of Botulism, 2021

MMWR Recommendations and Reports, 2021
Summary Botulism is a rare, neurotoxin-mediated, life-threatening disease characterized by flaccid descending paralysis that begins with cranial nerve palsies and might progress to extremity weakness and respiratory failure.
A. Rao, J. Sobel, K. Chatham-Stephens, C. Lúquez   +3 more
semanticscholar   +1 more source

Human and animal botulism surveillance in France from 2008 to 2019

Frontiers in Public Health, 2022
Botulism is a human and animal neurological disease caused by the action of bacterial neurotoxins (botulinum toxins) produced by bacteria from the genus Clostridium.
S. Le Bouquin, C. Lucas, R. Souillard, C. Le Maréchal, K. Petit, P. Kooh, N. Jourdan-Da Silva, F. Meurens, L. Guillier, C. Mazuet   +9 more
semanticscholar   +1 more source

Genomic and Phenotypic Characterization of Clostridium botulinum Isolates from an Infant Botulism Case Suggests Adaptation Signatures to the Gut

mBio, 2022
While the clinical aspects of infant botulism and the mode of action of BoNT have been thoroughly investigated, little is known on the pathogenesis and adaptive mechanisms of C. botulinum in the gut.
François P Douillard, Y. Derman, C. Woudstra, Katja Selby, Tommi Mäklin, M. B. Dorner, H. Saxén, B. Dorner, H. Korkeala, M. Lindström   +9 more
semanticscholar   +1 more source

Foodborne botulism: A brief review of cases transmitted by cheese products (Review)

Biomedical Reports, 2022
Food safety constitutes a basic priority for public health. Foodborne botulism occurs worldwide; it is an acute paralytic disease caused by the consumption of food containing the botulinum toxin.
E. Chaidoutis, D. Keramydas, P. Papalexis, A. Migdanis, I. Migdanis, Andreas C. Lazaris, N. Kavantzas   +6 more
semanticscholar   +1 more source

Neuronal delivery of antibodies has therapeutic effects in animal models of botulism

Science Translational Medicine, 2021
Intraneuronal delivery of a therapeutic, single-domain antibody reverses botulism symptoms and increases survival of mice, guinea pigs, and monkeys. Nontoxic botulinum for drug delivery Botulism is a severe and potentially fatal disease characterized by ...
P. McNutt, Edwin J. Vazquez-Cintron, Luis Tenezaca, Celinia A. Ondeck, Kyle E. Kelly, Mark Mangkhalakhili, James B. Machamer, Christopher A. Angeles, Elliot J. Glotfelty, Jaclyn Cika, Cesar H. Benjumea, Justin T. Whitfield, P. Band, C. Shoemaker, K. Ichtchenko   +14 more
semanticscholar   +1 more source

Foodborne Botulism Outbreaks in the United States, 2001–2017

Frontiers in Microbiology, 2021
Foodborne botulism is an intoxication caused by ingestion of food containing botulinum neurotoxin. Cases of foodborne botulism are usually sporadic (single, unrelated) but outbreaks of two or more cases occur.
C. Lúquez, L. Edwards, Chelsey Griffin, J. Sobel   +3 more
semanticscholar   +1 more source

A summary of surveillance, morbidity and microbiology of laboratory-confirmed cases of infant botulism in Canada, 1979-2019.

Canada communicable disease report = Releve des maladies transmissibles au Canada, 2021
Background Infant botulism is a rare toxicoinfectious disease caused by colonization of the infant's intestine with botulinum neurotoxin-producing clostridia (i.e. Clostridium botulinum or neurotoxigenic strains of C. butyricum or C. baratii).
Richard A. Harris, Christine Tchao, N. Prystajecky, J. Cutler, J. Austin   +4 more
semanticscholar   +1 more source

Use of Botulism Antitoxin Heptavalent (A, B, C, D, E, F, G)—(Equine) (BAT®) in Clinical Study Subjects and Patients: A 15-Year Systematic Safety Review

Toxins, 2021
Botulism is a rare, sometimes fatal paralytic illness caused by botulinum neurotoxins. BAT® (Botulism Antitoxin Heptavalent (A, B, C, D, E, F, G)—(Equine)) is an equine-derived heptavalent botulinum antitoxin indicated for the treatment of symptomatic ...
Geraldine S. Parrera, Hugo Astacio, Priya Tunga, Deborah M. Anderson, Christine Hall, Jason S Richardson   +5 more
semanticscholar   +1 more source

Current Developments in Diagnostic Assays for Laboratory Confirmation and Investigation of Botulism

Journal of Clinical Microbiology, 2021
Detection of botulinum neurotoxin or isolation of the toxin-producing organism is required for the laboratory confirmation of botulism in clinical specimens.
Dominick A. Centurioni, C. Egan, Michael J. Perry   +2 more
semanticscholar   +1 more source