Results 51 to 60 of about 31,212 (292)

Effects of guanidine on synaptic transmission in the spinal cord of the frog [PDF]

, 1977
The effects of guanidine on motoneurons of the isolated frog spinal cord were studied by adding the drug to the solution bathing the cord during intracellular recording. Guanidine (5·10–4 M) did not alter the membrane potential of motoneurons.
A. K�hner, B. Katz, E. Gergens, E. H. Lambert, F. Colomo, F. H. Norris, H. Ter�v�inen, J. I. Simpson, K. Koizumi, K. Ricker, M. A. Kamenskaya, M. A. Kamenskaya, M. Otsuka, P. Grafe, R. C. Scaer, S. D. Erulkar, S. J. Oh, U. Sonnhof, U. Sonnhof, W. C. Wiederholt   +19 more
core   +1 more source

Wound Botulism Among Persons Who Inject Black Tar Heroin in New Mexico, 2016

Frontiers in Public Health, 2021
Outbreaks of wound botulism are rare, but clinicians and health departments should maintain suspicion for signs, symptoms, and risk factors of wound botulism among persons who inject drugs in order to initiate treatment quickly.
Nicole Middaugh, L. Edwards, K. Chatham-Stephens, D. Arguello   +3 more
semanticscholar   +1 more source

Foodborne Botulism in the Republic of Georgia

Emerging Infectious Diseases, 2004
Foodborne botulism is a potentially fatal, paralytic illness that can cause large outbreaks. A possible increase in botulism incidence during 2001 in Georgia prompted this study.
Jay K. Varma, Guram Katsitadze, Maia Moiscrafishvili, Tamar Zardiashvili, Maia Chokheli, Natalia Tarkhashvili, Ekaterina Jhorjholiani, Maia Chubinidze, Teimuraz Kukhalashvili, Irakli Khmaladze, Nelli Chakvetadze, Paata Imnadze, Jeremy Sobel   +12 more
doaj   +1 more source

Immunological Characterization and Neutralizing Ability of Monoclonal Antibodies Directed Against Botulinum Neurotoxin Type H. [PDF]

, 2016
BackgroundOnly Clostridium botulinum strain IBCA10-7060 produces the recently described novel botulinum neurotoxin type H (BoNT/H). BoNT/H (N-terminal two-thirds most homologous to BoNT/F and C-terminal one-third most homologous to BoNT/A) requires ...
Arnon, Stephen S, Barash, Jason R, Conrad, Fraser, Fan, Yongfeng, Lou, Jianlong, Marks, James D   +5 more
core   +1 more source

Botulism in the 21st Century: A Scoping Review

Brown Journal of Hospital Medicine, 2023
Botulism is a potentially deadly neuroparalytic disease that affects all age groups; it is highly challenging to diagnose due to its nonspecific symptoms. Infant botulism is the most common form of botulism in the United States, followed by foodborne and
Ketino Kobaidze, Zanthia Wiley
doaj  

Infant Botulism: In Search of Clostridium botulinum Spores

Current Microbiology
Infant botulism is now the most common form of human botulism in Canada and the United States. Infant botulism is a severe neuroparalytic disease caused by ingestion of the spore-forming neurotoxic clostridia, including Clostridium botulinum that ...
Richard A. Harris, H. Dabritz
semanticscholar   +1 more source

Pan-Genomic Analysis of Clostridium botulinum Group II (Non-Proteolytic C. botulinum) Associated with Foodborne Botulism and Isolated from the Environment

Toxins, 2020
The neurotoxin formed by Clostridium botulinum Group II is a major cause of foodborne botulism, a deadly intoxication. This study aims to understand the genetic diversity and spread of C. botulinum Group II strains and their neurotoxin genes.
J. Brunt, A. H. V. van Vliet, S. Stringer, A. T. Carter, M. Lindström, M. Peck   +5 more
semanticscholar   +1 more source

Adult Intestinal Botulism: A Rare Presentation in an Immunocompromised Patient With Short Bowel Syndrome

Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 2018
The cholinergic heat-labile neurotoxin produced by Clostridium species is primarily responsible for the clinical manifestations of botulism. The classic phenotypic presentation of botulism consists of subacute descending flaccid paralysis with intact ...
Pramod K. Guru, MBBS, MD, Tara L. Becker, MD, Alana Stephens, DO, Rocco J. Cannistraro, MD, Benjamin H. Eidelman, MD, D. Jane Hata, PhD, Lisa Brumble, MD   +6 more
doaj   +1 more source

Clinical cases of atypical and severe botulism

Zaporožskij Medicinskij Žurnal, 2020
The aim of the work was to present two clinical cases of botulism: the atypical course and the severe course with late administration of heptavalent botulinum antitoxin, which still had a significant positive clinical effect and contributed to a faster ...
O. L. Ivakhiv, N. Yu. Vyshnevska
doaj   +1 more source

Local outbreak of foodborne botulism in Krasnoyarsk

Детские инфекции (Москва), 2023
Botulism is a serious infectious disease that has not lost its relevance today. Due to the widespread popularity of home canning, botulism is widespread everywhere, more often recorded in the form of sporadic cases and small (local) outbreaks.
G. P. Martynova, A. A. Andreeva, Ya. A. Bogvilene, M. A. Stroganova, L. A. Ikkes, A. V. Karasev, L. P. Alyeva, D. V. Bogatyrev   +7 more
doaj   +1 more source