Results 51 to 60 of about 23,713 (242)
Obesity is an increasingly common public health problem in children. The main goal in the fight against obesity is to prevent the development of obesity by healthy eating, increasing physical activity and reducing screen time.
Muhammed Furkan Yücer+3 more
doaj +1 more source
Abstract Botulism is a severe and often fatal disease in equine patients worldwide. Clostridium botulinum is a ubiquitous soil organism which produces a potent neurotoxin resulting in neuromuscular blockade and flaccid paralysis in affected animals. Definitive diagnosis is often impractical or impossible, leading to diagnosis and treatment based on ...
Kali Slavik+2 more
wiley +1 more source
A Targeted Therapeutic Rescues Botulinum Toxin-A Poisoned Neurons [PDF]
Botulinum neurotoxin (BoNT), a Category A biothreat agent, is the most potent poison known to mankind. Currently no antidote is available to rescue poisoned synapses.
Bal Ram Singh+6 more
core +1 more source
Botulinum toxin is the most potent toxin known to humans and as little as 100 ng can be lethal. The toxin blocks peripheral cholinergic neurotransmission at the neuromuscular junction and cholinergic autonomic nervous system by introducing an endopeptadase enzyme into the presynaptic side of the synapse.
openaire +6 more sources
The Role of Foxes in Transmitting Zoonotic Bacteria to Humans: A Scoping Review
ABSTRACT Zoonotic diseases inflict substantial burdens on human and animal populations worldwide, and many of these infections are bacterial. An Australian study investigating environmental risk factors for Buruli ulcer in humans detected the causative agent, Mycobacterium ulcerans, in the faeces of wild foxes, a novel finding that suggests foxes may ...
Emma C. Hobbs+6 more
wiley +1 more source
Safety and Pharmacokinetics of a Four Monoclonal Antibody Combination Against Botulinum C and D Neurotoxins. [PDF]
Botulism is caused by botulinum neurotoxin (BoNT), the most poisonous substance known. BoNTs are also classified as Tier 1 biothreat agents due to their high potency and lethality.
Cobb, Ronald R+12 more
core
Background. Human botulism is a serious, relatively rare and potencial lethal disease, caused by Clostridium botulinum, a gram positive obligat anaerobic spore forming bacili which strain produced seven potent nevrotoksins (type A-G).
Anica Berginc Dolenšek+4 more
doaj
Difficulties of differential diagnosis of botulism
The article presents the differential diagnosis of botulism with the most significant diseases similar to botulism, based on the classic symptoms of botulism: the connection of the disease with food intake, the absence of fever, progressive muscle ...
G. A. Kharchenko+2 more
doaj +1 more source
ABSTRACT Dysphagia is a prevalent symptom of the upper gastrointestinal tract causing health related consequences, impacting quality of life and is associated with global economic burden. Swallowing difficulties are classified into oropharyngeal dysphagia (OD) and esophageal dysphagia.
Amir Mari+45 more
wiley +1 more source
Wound Botulism in Black Tar Heroin Injecting Users: A Case Series
The incidence of wound botulism in injection drug users has increased since the introduction of black tar heroin. Many species of the Clostridium genus, most commonly Clostridium botulinum, Clostridium baratii , and Clostridium butyricum , have been ...
Nadia Raza MD+8 more
doaj +1 more source