Results 21 to 30 of about 721,610 (311)

Investigation of the interaction between indigotin and two serum albumins by spectroscopic approaches

Journal of Pharmaceutical Analysis, 2013
The binding characteristics of indigotin with human serum albumin (HSA) and bovine serum albumin (BSA) have been investigated by various spectroscopic techniques.
Zheng-Jun Cheng, Hong-Mei Zhao, Qian-Yong Xu, Rong Liu   +3 more
doaj   +1 more source

Serum albumin binding knob domains engineered within a VH framework III bispecific antibody format and as chimeric peptides

Frontiers in Immunology, 2023
BackgroundSerum albumin binding is an established mechanism to extend the serum half-life of antibody fragments and peptides. The cysteine rich knob domains, isolated from bovine antibody ultralong CDRH3, are the smallest single chain antibody fragments ...
Ralph Adams, Callum Joyce, Mikhail Kuravskiy, Katriona Harrison, Katriona Harrison, Zainab Ahdash, Matthew Balmforth, Kelda Chia, Cinzia Marceddu, Matthew Coates, James Snowden, Emmanuel Goursaud, Karelle Ménochet, Jean van den Elsen, Richard J. Payne, Richard J. Payne, Alastair D. G. Lawson, Anthony Scott-Tucker, Alex Macpherson   +18 more
doaj   +1 more source

A large potentiation effect of serum on the in vitro potency of tulathromycin against Mannheimia haemolytica and Pasteurella multocida [PDF]

, 2017
The antimicrobial properties of tulathromycin were investigated for M.haemolytica and P.multocida. Three invitro indices of antimicrobial activity, minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and time-kill curves ...
Alexander, Andersen, Brentnall, Craig, Evans, Ferran, Godinho, Godinho, Godinho, Kesteman, Kiem, Mitchell, Mitchell, Nickell, Nightingale, Nowakowski, Perrett, Portis, Pruul, Radostits, Rerat, Robb, Rose, Schunicht, Step, Torres, Toutain, Tyndall, Van Donkersgoed, Van Donkersgoed, Villarino, Wellman, Zeitlinger, Zeitlinger   +33 more
core   +1 more source

Endogenous mammalian lectin localized extracellularly in lung elastic fibers. [PDF]

, 1984
An affinity-purified antibody preparation raised against a beta-galactoside-binding lectin from bovine lung was used to localize a similar lectin in rat lung by immunofluorescence and by electron microscopy after on-grid staining visualized with ...
Barondes, SH, Cerra, RF, Haywood-Reid, PL   +2 more
core   +3 more sources

Toward an Alternative Intrinsic Probe for Spectroscopic Characterization of a Protein [PDF]

, 2010
The intrinsic fluorescent amino acid tryptophan is the unanimous choice for the spectroscopic investigation of proteins. However, several complicacies in the interpretation of tryptophan fluorescence in a protein are inevitable and an alternative ...
Goswami, Nirmal, Makhal, Abhinandan, Pal, Samir Kumar   +2 more
core   +1 more source

New Asymmetric Gemini Triazole Surfactants with a Polar Triethylene Glycol Fragment: Synthesis and Physico-Chemical Properties

Molecules
The present work is devoted to the synthesis and analysis of the physicochemical properties of new functionalized asymmetric Gemini surfactants. Herein, alkyl- and azide-substituted surfactants with symmetric and asymmetric substituents were synthesized ...
Ilshat Bogdanov, Diana Mironova, Elza Sultanova, Vladimir Burilov, Svetlana Solovieva, Igor Antipin   +5 more
doaj   +1 more source

Study of Interactions of an Anticancer Drug Neratinib With Bovine Serum Albumin: Spectroscopic and Molecular Docking Approach

Frontiers in Chemistry, 2018
Binding of therapeutic agents to plasma proteins, particularly to serum albumin, provides valuable information in the drug development. This study was designed to evaluate the binding interaction of neratinib with bovine serum albumin (BSA).
Tanveer A. Wani, Ahmed H. Bakheit, Ahmed H. Bakheit, M. A. Abounassif, Seema Zargar   +4 more
doaj   +1 more source

Study of binding interaction of rivaroxaban with bovine serum albumin using multi-spectroscopic and molecular docking approach

Chemistry Central Journal, 2017
Background Rivaroxaban is a direct inhibitor of coagulation factor Xa and is used for venous thromboembolic disorders. The rivaroxaban interaction with BSA was studied to understand its PK and PD (pharmacokinetics and pharmacokinetics) properties.
Tanveer A. Wani, Haitham AlRabiah, Ahmed H. Bakheit, Mohd Abul Kalam, Seema Zargar   +4 more
doaj   +1 more source

Cell patterning on photolithographically defined parylene-C:SiO2 substrates [PDF]

, 2014
Cell patterning platforms support broad research goals, such as construction of predefined in vitro neuronal networks and the exploration of certain central aspects of cellular physiology.
Brennan, Paul M, Bunting, Andrew S, Hughes, Mark A, Murray, Alan F, Shipston, Mike J   +4 more
core   +2 more sources

Adjuvant properties of polymer based on acrylic acid [PDF]

The Ukrainian Biochemical Journal, 2013
Adjuvant properties of the polymer containing­ acrylic acid, glycidyl methacrylate, triethylene glycol methacrylate and butyl acrylate have been established.
M. R. Kozak, A. V. Oliynyk, O. S. Zaichenko, V. V. Vlizlo   +3 more
doaj   +1 more source