Results 161 to 170 of about 5,574 (175)
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The reducing component BoxA of benzoyl-coenzyme A epoxidase from Azoarcus evansii is a [4Fe–4S] protein

Biochimica Et Biophysica Acta - Proteins and Proteomics, 2011
BoxA is the reductase component of the benzoyl-coenzyme A (CoA) oxidizing epoxidase enzyme system BoxAB. The enzyme catalyzes the key step of an hitherto unknown aerobic, CoA-dependent pathway of benzoate metabolism, which is the epoxidation of benzoyl-CoA to the non-aromatic 2,3-epoxybenzoyl-CoA.
Wael Ahmed Ismail
exaly   +3 more sources

High mobility group box-1 (HMGB1) antagonist BoxA suppresses status epilepticus-induced neuroinflammatory responses associated with Toll-like receptor 2/4 down-regulation in rats

Brain Research, 2019
It has been generally accepted that inflammatory responses induced by status epilepticus (SE) in the brain are associated with microglial activation. One important regulator of microglial activation is high mobility group box-1 (HMGB1) protein. HMGB1 exerts its influence on microglia via various pathways including Toll-like receptor (TLR) subtypes 2 ...
Andrius Baskys, Weiping Liu
exaly   +3 more sources

Abstract 5557: BoxA and ethyl pyruvate offer novel therapeutic approaches for human malignant mesothelioma.

Cancer Research, 2013
Abstract Human malignant mesothelioma (MM) is an aggressive and highly lethal cancer that has been linked to asbestos and erionite exposure. MM causes about 3,000 deaths per year in the US and more than 100,000 deaths per year worldwide.
Sandro L. Jube   +7 more
openaire   +1 more source

Boundaries of the nutL antiterminator of coliphage lambda and effects of mutations in the spacer region between boxA and boxB

Gene, 1986
To study the relationship of sequence to function for the phage lambda nutL transcriptional antiterminator, we cloned the 354-bp HincII lambda DNA fragment (coordinates 35261-35615; Daniels et al., in Lambda II, 1983, pp. 485-486 and 618-619) between the plac promoter and Rho-dependent or Rho-independent terminators (t) in the plac-t-galK plasmid ...
N, Hasan, W, Szybalski
openaire   +2 more sources

Transcriptional antitermination activity of the synthetic nut elements of coliphage lambda I. Assembly of thenutR recognition site from boxA and nut core elements

Gene, 1985
An active nutR antiterminator was reconstructed from two synthetic modules, one containing the 8-bp boxA (5'-CGCTCTTA) and the other the 17-bp nutR core (5'-AGCCCTGAAAAAGGGCA) sequence. The modules were synthesized with HindIII cohesive ends, which upon annealing and ligation created an 8-bp spacer (5'-CAAAGCTT) between the boxA and nutR core. The 8-bp
A L, Brown, W, Szybalski
openaire   +3 more sources

The Role of Boxa in Transcription of Ribosomal RNA Operons of Eschericha Coli: Changes in the Processivity of RNA Polymerase

1990
Termination of transcription by the RNA polymerase of E. coli is generally assumed to be quite limited in the absence of deliberate transcription termination signals. However, the inherent termination rate of RNA polymerase in the absence of deliberate termination signals (what we will refer to as the processivity of RNA polymerase) has not been ...
R. J. Gaudino, E. A. Morgan
openaire   +1 more source

Fine tuning of the E. coli NusB:NusE complex affinity to BoxA RNA is required for processive antitermination

Nucleic Acids Research, 2010
Björn M Burmann   +2 more
exaly  

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