Results 11 to 20 of about 4,291 (203)

Glucocorticoids Combined with Methotrexate in the Treatment of Psoriasis Merged with Bullous Pemphigoid: A Case Report and Literature Review. [PDF]

Clin Case Rep
Clinical Case Reports, Volume 14, Issue 3, March 2026.
Ma W, Li C, Miao H.
europepmc   +2 more sources

Foot-and-Mouth Disease Virus 3C^pro Cleaves BP180 to Induce Blister Formation

Viruses, 2022
Foot-and-mouth disease (FMD) is mainly characterized by blister formation (vesicles) in animals infected with foot-and-mouth disease virus (FMDV). However, the molecular basis of the blister formation in FMD is still unknown.
Pathum Ekanayaka, Asela Weerawardhana, Kiramage Chathuranga, Jong-Hyeon Park, Jong-Soo Lee   +4 more
doaj   +1 more source

Sita- and saxagliptin use and autoantibodies to autoimmune bullous diseases: A cross-sectional study. [PDF]

J Eur Acad Dermatol Venereol
Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 4, Page e227-e230, April 2026.
Dräger S, Kauderer C, Meyhöfer S, Dräger L, Marquardt JU, Ludwig RJ, Arndt S, Boch K, Bieber K.   +8 more
europepmc   +2 more sources

Type XVII collagen: Relevance of distinct epitopes, complement-independent effects, and association with neurological disorders in pemphigoid disorders

Frontiers in Immunology, 2022
Pemphigoid diseases (PD) are autoimmune skin blistering diseases characterized by autoantibodies directed against proteins of the cutaneous basement membrane zone (BMZ).
Bianca Opelka, Enno Schmidt, Enno Schmidt, Stephanie Goletz   +3 more
doaj   +1 more source

BP180 gene delivery in junctional epidermolysis bullosa [PDF]

Gene Therapy, 1999
Epidermolysis bullosa (EB) comprises a family of inherited blistering skin diseases for which current therapy is only palliative. Junctional EB (JEB) involves dissociation of the dermal-epidermal junction and results from mutations in a number of genes that encode vital structural proteins, including BP180 (type XVII collagen/BPAG2).
C S, Seitz, G J, Giudice, S D, Balding, M P, Marinkovich, P A, Khavari   +4 more
openaire   +2 more sources

Autoreactive Peripheral Blood T Helper Cell Responses in Bullous Pemphigoid and Elderly Patients With Pruritic Disorders

Frontiers in Immunology, 2021
Bullous pemphigoid (BP) is a prototypic autoimmune disorder of the elderly, characterized by serum IgG autoantibodies, namely anti-BP180 and anti-BP230, directed against components of the basal membrane zone that lead to sub-epidermal loss of adhesion ...
Dario Didona, Luca Scarsella, Milad Fehresti, Farzan Solimani, Farzan Solimani, Hazem A. Juratli, Manuel Göbel, Stefan Mühlenbein, Lily Holiangu, Josquin Pieper, Vera Korff, Thomas Schmidt, Cassian Sitaru, Rüdiger Eming, Michael Hertl, Robert Pollmann   +15 more
doaj   +1 more source

Bullous Pemphigoid in Children: Sustained 8-Year Remission After Short-Course Corticosteroid Therapy. [PDF]

Clin Case Rep
ABSTRACT This article reports a case of bullous pemphigoid (BP) in a 5‐year‐old child who achieved sustained remission for up to 8 years following short‐course systemic corticosteroid therapy, aiming to provide observational evidence for the clinical management of childhood BP. The child initially presented with pruritic rashes and blisters, which were
Wang F, Li H, Xu Y, Wang W.
europepmc   +2 more sources

Rapid Disease Control in First-Line Therapy-Resistant Mucous Membrane Pemphigoid and Bullous Pemphigoid with Omalizumab as Add-On Therapy: A Case Series Of 13 Patients

Frontiers in Immunology, 2022
The role of IgE autoantibodies has been demonstrated in the pathogenesis of bullous pemphigoid for many years. Recently, omalizumab (OMZ), a humanized monoclonal anti-IgE antibody that depletes total serum IgE, has been used off-label in a few case ...
Marina Alexandre, Gérôme Bohelay, Gérôme Bohelay, Thomas Gille, Thomas Gille, Christelle Le Roux-Villet, Isaac Soued, Florence Morin, Frédéric Caux, Frédéric Caux, Sabine Grootenboer-Mignot, Catherine Prost-Squarcioni, Catherine Prost-Squarcioni, Catherine Prost-Squarcioni   +13 more
doaj   +1 more source

BP180 dysfunction triggers spontaneous skin inflammation in mice [PDF]

Proceedings of the National Academy of Sciences, 2018
Significance BP180 is a cell–cell matrix adhesion molecule and is critical for attachment of epidermis to underlying dermis. We generated a dysfunctional BP180 mouse strain (Δ NC16A mice).
Yang Zhang, Bin-Jin Hwang, Zhen Liu, Ning Li, Kendall Lough, Scott E. Williams, Jinbo Chen, Susan W. Burette, Luis A. Diaz, Maureen A. Su, Shengxiang Xiao, Zhi Liu   +11 more
openaire   +2 more sources

Insights Into the Pathogenesis of Bullous Pemphigoid: The Role of Complement-Independent Mechanisms

Frontiers in Immunology, 2022
Bullous pemphigoid is an autoimmune blistering disease caused by autoantibodies targeting BP180 and BP230. While deposits of IgG and/or complement along the epidermal basement membrane are typically seen suggesting complement -mediated pathogenesis ...
Connor Cole, Keshavamurthy Vinay, Luca Borradori, Kyle T. Amber, Kyle T. Amber   +4 more
doaj   +1 more source