Results 21 to 30 of about 1,796 (202)

Blastic Plasmacytoid Dendritic Cell Neoplasm Mimicking Erythema Nodosum: A Case Report

Annals of Internal Medicine: Clinical Cases, 2023
Blastic plasmacytoid dendritic cell neoplasm (BPDCN), previously known as blastic natural killer cell lymphoma, is a rare, difficult-to-diagnose, and aggressive hematologic malignancy.
Marino Hirata, Nozomu Yoshino, Maya Takazawa, Hisashi Oshiro, Shinichi Kako, Hitoshi Sugawara   +5 more
doaj   +1 more source

Blastic plasmacytoid dendritic cell neoplasm with genetic mutations in multiple epigenetic modifiers: a case report

Journal of International Medical Research, 2021
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, aggressive hematodermic malignancy derived from plasmacytoid dendritic cell precursors. Despite advances in our understanding of tumor cell surface markers, the pathogenesis of BPDCN remains
Xinmei Dang, Di Zhou, Lingjun Meng, Lintao Bi   +3 more
doaj   +1 more source

Blastic plasmacytoid dendritic cell neoplasm (BPDCN)

Hematology, Transfusion and Cell Therapy, 2023
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy with an aggressive clinical course and poor prognosis. BPDCN is most often characterized by its presentation with cutaneous lesions which are often asymptomatic, can be solitary or multiple lesions, can be distributed widely, and may range from bruise-like lesions to ...
openaire   +3 more sources

Petechiae and a Persistent Violaceous Nodule: A Presentation of Blastic Plasmacytoid Dendritic Cell Neoplasm to Dermatology. [PDF]

Case Rep Dermatol Med
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, highly aggressive CD4+ CD56+ hematopoietic malignancy. The cutaneous presentation is variable but often includes violaceous nodules.
Anzelc M, Druskovich C, Cusick A, Franklin M.   +3 more
europepmc   +2 more sources

Blastische plasmazytoide dendritische Zellneoplasie (BPDCN)

Die Dermatologie, 2023
ZusammenfassungDie blastische plasmazytoide dendritische Zellneoplasie ist eine seltene hämatologische Neoplasie, die aus Vorläuferzellen der plasmazytoiden dendritischen Zellen entsteht und durch disseminierte, erythematöse bis bläulich-livide Plaques oder Nodi gekennzeichnet ist.
Nguyen, Katrin, Korsing, Sören, Mansour, Yasmine, Meier, Katharina   +3 more
openaire   +1 more source

Single-Cell Multiomics Reveals Clonal T-Cell Expansions and Exhaustion in Blastic Plasmacytoid Dendritic Cell Neoplasm

Frontiers in Immunology, 2022
The immune system represents a major barrier to cancer progression, driving the evolution of immunoregulatory interactions between malignant cells and T-cells in the tumor environment.
Erica A. K. DePasquale, Erica A. K. DePasquale, Erica A. K. DePasquale, Erica A. K. DePasquale, Daniel Ssozi, Daniel Ssozi, Marina Ainciburu, Jonathan Good, Jonathan Good, Jenny Noel, Jenny Noel, Martin A. Villanueva, Martin A. Villanueva, Martin A. Villanueva, Martin A. Villanueva, Martin A. Villanueva, Martin A. Villanueva, Charles P. Couturier, Charles P. Couturier, Charles P. Couturier, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Sary F. Aranki, Hari R. Mallidi, Gabriel K. Griffin, Gabriel K. Griffin, Gabriel K. Griffin, Andrew A. Lane, Andrew A. Lane, Andrew A. Lane, Andrew A. Lane, Peter van Galen, Peter van Galen, Peter van Galen, Peter van Galen   +38 more
doaj   +1 more source

Tissue-Resident Myeloid and Histiocytic Cells in Health and Disease: Novel Emerging Concepts. [PDF]

Am J Hematol
ABSTRACT Although all myeloid cells are considered to derive from hematopoietic stem cells, the cells in each myeloid lineage are heterogeneous populations, and their distribution and functions vary, depending on underlying physiologic and pathologic processes, age, sex, and genetic and epigenetic signatures.
Valent P, Wojta J, Kovanen PT, Hermine O, Fend F, Sotlar K, Greinix H, Geissler K, Hartmann K, Schwaab J, Herling M, Boccuni L, Kazianka L, John MV, Sperr WR, Zierfuss C, Tzankov A, Sillaber C, Minkov M, Hoermann G, Collin M, Horny HP, Haferlach T, Sibilia M, Haroche J, La Rosée P, Orfao A, Arock M.   +27 more
europepmc   +2 more sources

Immunophenotypic characterization of reactive and neoplastic plasmacytoid dendritic cells permits establishment of a 10-color flow cytometric panel for initial workup and residual disease evaluation of blastic plasmacytoid dendritic cell neoplasm

Haematologica, 2020
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematopoietic neoplasm whose immunophenotype remains incompletely characterized, particularly in terms of distinction from reactive plasmacytoid dendritic cells (PDCs).
Wei Wang, Joseph D. Khoury, Roberto N. Miranda, Jeffrey L. Jorgensen, Jie Xu, Sanam Loghavi, Shaoying Li, Naveen Pemmaraju, Than Nguyen, L. Jeffrey Medeiros, Sa A. Wang   +10 more
doaj   +1 more source

Blastic plasmacytoid dendritic cell neoplasm (BPDCN): international, multi-center collaboration and global registry program. [PDF]

Discov Oncol
Background Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) is a rare and aggressive hematologic malignancy originating from plasmacytoid dendritic cell precursors.
Voskanyan A, Badikyan M, Konopleva M, Alencar A, Ivanyan A, Owen C, Sergi CM, Peng CT, Kazandjian D, Taylor J, Tekkesin F, Ghali H, Bedirian K, Martelli MP, Attardi E, Voso MT, Abramashvili M, Al-Jadiry MF, Michael M, Su MY, Martirosyan N, Ghahramanyan N, Totogashvili N, Kotoucek PP, Kebudi R, Ohannessian R, Papyan R, Hovsepyan S, Elashwah S, Bakhshi S, Bardakhchyan S, Danelyan S, El-Ashwah S, Kutluk T, Tuğcu D, Alhuraiji A, Lazaris V, Tamamyan G, Pemmaraju N.   +38 more
europepmc   +2 more sources

Blastic plasmacytoid dendritic cell neoplasm (BPDCN): a rare entity [PDF]

BMJ Case Reports, 2016
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive haematological malignancy in the elderly, with a high frequency of cutaneous and bone marrow involvement and poor prognosis. We report a case of BPDCN with classic presentation and discuss its treatment and the value of different investigation tools used in diagnosis and ...
Ming Sheng, Lim, Karla, Lemmert, Anoop, Enjeti   +2 more
openaire   +2 more sources