Results 41 to 50 of about 1,494 (190)

Sex-Biased ZRSR2 Mutations in Myeloid Malignancies Impair Plasmacytoid Dendritic Cell Activation and Apoptosis [PDF]

, 2021
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an aggressive leukemia of plasmacytoid dendritic cells (pDC). BPDCN occurs at least three times more frequently in men than in women, but the reasons for this sex bias are unknown.
Lovitch S. B., Hammerman P. S., Angelot-Delettre F., Yang H., Konopleva M., Buonamici S., Garnache-Ottou F., Taylor J., Piccaluga P. P., Griffin G. K., Li J., Ghandi M., Morgan E. A., Seiler M., Togami K., Cabal-Hierro L., Madan V., Li Y. Y., Jardin F., Biichle S., Kenyon C. M., Pemmaraju N., Louissaint A., Weinstock D. M., Booth C. A. G., Chung S. S., Koeffler H. P., Abdel-Wahab O., Lane A. A., Kim S. S., Chung, Sun Sook, Lane, Andrew A, Morgan, Elizabeth A., Hammerman, Peter S, Buonamici, Silvia, Li, Yvonne Y, Louissaint, Abner, Pemmaraju, Naveen, Lovitch, Scott B., Ghandi, Mahmoud, Konopleva, Marina, Madan, Vikas, Yang, Henry, Louissaint, Jr, Abner, Weinstock, David M, Griffin, Gabriel K., Booth, Christopher AG, Kenyon, Christopher M, Koeffler, H Phillip, Griffin, Gabriel K, Angelot-Delettre, Fanny, Jardin, Fabrice, Morgan, Elizabeth A, Kim, Sunhee S, Kenyon, Christopher M., Cabal-Hierro, Lucia, Biichle, Sabeha, Booth, Christopher A G, Abdel-Wahab, Omar, Koeffler, H. Phillip, Weinstock, David M., Kim, Sunhee S., Seiler, Michael, Li, Yvonne Y., Garnache-Ottou, Francine, Lane, Andrew A., Taylor, Justin, Booth, Christopher A.G., Li, Jia, Lovitch, Scott B, Togami, Katsuhiro, Piccaluga, Pier Paolo, Hammerman, Peter S., Fanny Angelot-Delettre, David M. Weinstock, Scott B. Lovitch, Andrew A. Lane, Sunhee S. Kim, Katsuhiro Togami, Pier Paolo Piccaluga, Christopher M. Kenyon, Francine Garnache-Ottou, Yvonne Y. Li, Mahmoud Ghandi, Henry Yang, Peter S. Hammerman, Christopher A.G. Booth, Sabeha Biichle, Sun Sook Chung, Marina Konopleva, Gabriel K. Griffin, Justin Taylor, Naveen Pemmaraju, H. Phillip Koeffler, Silvia Buonamici, Elizabeth A. Morgan, Jia Li, Omar Abdel-Wahab, Fabrice Jardin, Michael Seiler, Vikas Madan, Lucia Cabal-Hierro, Abner Louissaint   +102 more
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An Unusual Manifestation of Blastic Plasmacytoid Dendritic Cell Neoplasm as a Testicular Tumor

Case Reports in Pathology, 2019
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a clinically aggressive hematologic malignancy arising from precursors of plasmacytoid dendritic cells that represent less than 1% of hematological malignancies.
Daniel M. Pak, Maria S. Tretiakova
doaj   +1 more source

Spatial Response to Pivekimab Sunirine (IMGN632) In Vivo in a BPDCN Model [PDF]

, 2023
peer reviewed Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, aggressive hematologic malignancy, which often manifests with skin lesions in addition to lymph node, blood, and bone marrow involvement.
Fredon, Maxime, Belakri, Imane, Sloss, Callum Mortimer, Watkins, Krystal, Garnache Ottou, Francine, Zweidler-McKay, Patrick A., Poussard, Margaux, Biichle, Sabeha, Renosi, Florian, Delettre, Fanny, Boichut, Morgane   +10 more
core   +1 more source

Blastic plasmacytoid dendritic cell neoplasm (BPDCN): a rare entity [PDF]

BMJ Case Reports, 2016
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive haematological malignancy in the elderly, with a high frequency of cutaneous and bone marrow involvement and poor prognosis. We report a case of BPDCN with classic presentation and discuss its treatment and the value of different investigation tools used in diagnosis and ...
Ming Sheng, Lim, Karla, Lemmert, Anoop, Enjeti   +2 more
openaire   +2 more sources

Blastische plasmazytoide dendritische Zellneoplasie (BPDCN)

Die Dermatologie, 2023
ZusammenfassungDie blastische plasmazytoide dendritische Zellneoplasie ist eine seltene hämatologische Neoplasie, die aus Vorläuferzellen der plasmazytoiden dendritischen Zellen entsteht und durch disseminierte, erythematöse bis bläulich-livide Plaques oder Nodi gekennzeichnet ist.
Nguyen, Katrin, Korsing, Sören, Mansour, Yasmine, Meier, Katharina   +3 more
openaire   +2 more sources

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) arising in the setting of polycythemia vera (PV): An illustration of the emerging role of flow cytometry analysis in monitoring progression of myeloproliferative neoplasms

, 2022
This report highlights the value of flow cytometry analysis, particularly in the setting of myeloproliferative neoplasms showing features of progression, as neoplastic plasmacytoid dendritic cell (PDC) proliferations may be present, representing either a
Evans, Andrew G., Hong Fang, Wang, Wei, Siba El Hussein, John M. Bennett, Naveen Pemmaraju, Andrew G. Evans, Fang, Hong, El Hussein, Siba, Jane L. Liesveld, W. Richard Burack, Medeiros, L. Jeffrey, Bennett, John M., Sanam Loghavi, Fatima Zahra Jelloul, Loghavi, Sanam, Burack, W. Richard, Mariko Yabe, Wei Wang, L. Jeffrey Medeiros, Yabe, Mariko, Pemmaraju, Naveen, Liesveld, Jane L., Jelloul, Fatima Zahra   +23 more
core   +1 more source

A Rare Case of Blastic Plasmacytoid Dendritic Cell Neoplasm Occurred in Postchemotherapy of Breast Cancer

Case Reports in Hematology, 2023
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and highly aggressive hematologic malignancy that arises from plasmacytoid dendritic cells.
Jiankun Tong, Sergei Aksenov, Beth M. Siegel, Lihong Wei, William H. Rodgers   +4 more
doaj   +1 more source

High ORRs Seen with Tagraxofusp-erzs in BPDCN [PDF]

Cancer Discovery, 2019
Abstract Tagraxofusp-erzs is an effective therapy for blastic plasmacytoid dendritic-cell neoplasm, according to recently published results from a multistage trial that led to the drug's 2018 approval. In the trial, the drug elicited high overall response rates, and many patients went on to receive a stem-cell transplant.
openaire   +1 more source

Severe tumor lysis syndrome during the induction therapy for the treatment of blastic plasmacytoid dendritic cell neoplasm arising from myelodysplastic/myeloproliferative neoplasms

Clinical Case Reports, 2021
BPDCN shows clinically heterogeneous characteristics. And as other hematological malignancies, symptoms of BPDCN suggesting a high tumor burden, such as high white blood cell count or splenomegaly, should be carefully considered to prevent TLS.
Ken Sagou, Makoto Ito, Yuma Kawamura, Shun Ukai, Miyo Goto, Nobuaki Fukushima, Kazutaka Ozeki, Ryuichi Fukuyama, Akio Kohno   +8 more
doaj   +1 more source

A case report on BPDCN: Blastic Plasmacytoid Dendritic Cell Neoplasm

World Journal of Advanced Research and Reviews, 2023
Dendritic cells are present in both lymphoid and non-lymphoid organs, which are heterogenous group of nonphagocytic and nonlymphoid immune accessory cells. Plasmacytoid dendritic cell (which has an eccentric nuclei) are subset of dendritic cells aid in secreting high levels of type 1 interferons by activation and gaining dendritic cell like morphology,
Mercy Paul M, Sukumar Naidu KD
openaire   +2 more sources