Primary blastic plasmacytoid dendritic cell neoplasm: a US population-based study
Frontiers in Oncology, 2023 BackgroundBlastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and poorly understood hematopoietic malignancy. This study aimed to investigate the clinical characteristics and prognostic factors in patients with primary BPDCN.MethodsPatients ...
Lifang Huang, Fan Wang
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Disseminated histiocytoses biomarkers beyond BRAFV600E: frequent expression of PD-L1. [PDF]
, 2015 The histiocytoses are rare tumors characterized by the primary accumulation and tissue infiltration of histiocytes and dendritic cells. Identification of the activating BRAFV600E mutation in Erdheim-Chester disease (ECD) and Langerhans cell histiocytosis
Arceci, Robert J +8 more
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Blastic plasmacytoid dendritic cell neoplasm complicated with acute myeloid leukemia: a case report [PDF]
Xin yixue, 2023 Blastic plasmacytoid dendritic cell neoplasm （BPDCN） complicated with acute myeloid leukemia （AML） is a rare disease. In this article， we reported the diagnosis and treatment of one patient of BPDCN complicated with AML who presented with fever as the ...
Kong Lihua, Qin Lili, Feng Anhua, Liu Zhenzhen, Tang Na, Zang Jikang, Wang Haiying
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Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors [PDF]
, 2017 Dendritic cells (DCs) and monocytes play a central role in pathogen sensing, phagocytosis, and antigen presentation and consist of multiple specialized subtypes. However, their identities and interrelationships are not fully understood.
Butler, Andrew +23 more
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Whole-genome analysis uncovers recurrent IKZF1 inactivation and aberrant cell adhesion in blastic plasmacytoid dendritic cell neoplasm [PDF]
, 2020 Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and highly aggressive hematological malignancy with a poorly understood pathobiology and no effective therapeutic options.
A.N. Bastidas Torres +10 more
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Blastic Plasmacytoid Dendritic Cell Neoplasm; A Report of Three Cases [PDF]
Iranian Journal of Medical Sciences, 2019 Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematodermic myeloid malignancy that is known to be derived from plasmacytoid dendritic cells which are characterized by expression of CD4, CD56, and more specific markers such as CD123. Here,
Akbar Safaei +4 more
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Targeting leukemia stem cells in the bone marrow niche [PDF]
, 2018 The bone marrow (BM) niche encompasses multiple cells of mesenchymal and hematopoietic origin and represents a unique microenvironment that is poised to maintain hematopoietic stem cells.
Bertaina +13 more
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Leukemia Research Reports, 2022 Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) is a very rare type of leukemia in children, Although BPDCN is a chemo-sensitive tumor, the relapse rate is very high.
Dima Abla +4 more
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ZEB proteins in leukemia : friends, foes, or friendly foes? [PDF]
, 2018 . ZEB1 and ZEB2 play pivotal roles in solid cancer metastasis by allowing cancer cells to invade and disseminate through the transcriptional regulation of epithelial-to-mesenchymal transition.
Berx, Geert +5 more
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An Unusual Manifestation of Blastic Plasmacytoid Dendritic Cell Neoplasm as a Testicular Tumor
Case Reports in Pathology, 2019 Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a clinically aggressive hematologic malignancy arising from precursors of plasmacytoid dendritic cells that represent less than 1% of hematological malignancies.
Daniel M. Pak, Maria S. Tretiakova
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