Results 31 to 40 of about 1,440 (183)

Spatial Response to Pivekimab Sunirine (IMGN632) In Vivo in a BPDCN Model [PDF]

, 2023
peer reviewed Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, aggressive hematologic malignancy, which often manifests with skin lesions in addition to lymph node, blood, and bone marrow involvement.
Fredon, Maxime, Belakri, Imane, Sloss, Callum Mortimer, Watkins, Krystal, Garnache Ottou, Francine, Zweidler-McKay, Patrick A., Poussard, Margaux, Biichle, Sabeha, Renosi, Florian, Delettre, Fanny, Boichut, Morgane   +10 more
core   +1 more source

Blastic plasmacytoid dendritic cell neoplasm with genetic mutations in multiple epigenetic modifiers: a case report

Journal of International Medical Research, 2021
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, aggressive hematodermic malignancy derived from plasmacytoid dendritic cell precursors. Despite advances in our understanding of tumor cell surface markers, the pathogenesis of BPDCN remains
Xinmei Dang, Di Zhou, Lingjun Meng, Lintao Bi   +3 more
doaj   +1 more source

Single-Cell Multiomics Reveals Clonal T-Cell Expansions and Exhaustion in Blastic Plasmacytoid Dendritic Cell Neoplasm

Frontiers in Immunology, 2022
The immune system represents a major barrier to cancer progression, driving the evolution of immunoregulatory interactions between malignant cells and T-cells in the tumor environment.
Erica A. K. DePasquale, Erica A. K. DePasquale, Erica A. K. DePasquale, Erica A. K. DePasquale, Daniel Ssozi, Daniel Ssozi, Marina Ainciburu, Jonathan Good, Jonathan Good, Jenny Noel, Jenny Noel, Martin A. Villanueva, Martin A. Villanueva, Martin A. Villanueva, Martin A. Villanueva, Martin A. Villanueva, Martin A. Villanueva, Charles P. Couturier, Charles P. Couturier, Charles P. Couturier, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Sary F. Aranki, Hari R. Mallidi, Gabriel K. Griffin, Gabriel K. Griffin, Gabriel K. Griffin, Andrew A. Lane, Andrew A. Lane, Andrew A. Lane, Andrew A. Lane, Peter van Galen, Peter van Galen, Peter van Galen, Peter van Galen   +38 more
doaj   +1 more source

Case Report: Early diagnostic precision matters: navigating therapeutic uncertainty in pediatric BPDCN illustrated by misdiagnosis sequelae and fleeting CAR-T response [PDF]

Frontiers in Pediatrics
Yuhua Qu
exaly   +2 more sources

Immunophenotypic characterization of reactive and neoplastic plasmacytoid dendritic cells permits establishment of a 10-color flow cytometric panel for initial workup and residual disease evaluation of blastic plasmacytoid dendritic cell neoplasm

Haematologica, 2020
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematopoietic neoplasm whose immunophenotype remains incompletely characterized, particularly in terms of distinction from reactive plasmacytoid dendritic cells (PDCs).
Wei Wang, Joseph D. Khoury, Roberto N. Miranda, Jeffrey L. Jorgensen, Jie Xu, Sanam Loghavi, Shaoying Li, Naveen Pemmaraju, Than Nguyen, L. Jeffrey Medeiros, Sa A. Wang   +10 more
doaj   +1 more source

Anti-CD123 CAR-T therapy combined with autologous SCT and venetoclax maintenance in refractory BPDCN ineligible for allogeneic transplantation: a case report and review of the literature. [PDF]

Front Immunol
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an aggressive hematologic malignancy with limited therapeutic options for patients ineligible for allogeneic hematopoietic stem cell transplantation (allo-HSCT).
Yang F, Li D, Lei Y, Liu R, Fu Z, Ma L, Deng B, Ke X, Hu K.   +8 more
europepmc   +2 more sources

Blastic Plasmacytoid Dendritic Cell Neoplasm BPDCN

Hematology, Transfusion and Cell Therapy, 2023
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy with an aggressive clinical course and poor prognosis. BPDCN is most often characterized by its presentation with cutaneous lesions which are often asymptomatic, can be solitary or multiple lesions, can be distributed widely, and may range from bruise-like lesions to ...
openaire   +3 more sources

Primary blastic plasmacytoid dendritic cell neoplasm: a US population-based study

Frontiers in Oncology, 2023
BackgroundBlastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and poorly understood hematopoietic malignancy. This study aimed to investigate the clinical characteristics and prognostic factors in patients with primary BPDCN.MethodsPatients ...
Lifang Huang, Fan Wang
doaj   +1 more source

Epidemiology and Survival Outcomes in Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN): A US Population-Based Study

, 2023
Background: Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, clinically aggressive hematological malignancy arising from plasmacytoid dendritic cell precursors.
Karki, Ujjwal, Poudel, Shyam K, Shah, Anish, Ghimire, Bipin, Budhathoki, Pravash, Muhsin Muhsin Chisti, Mohammad   +5 more
core   +3 more sources

Blastic plasmacytoid dendritic cell neoplasm complicated with acute myeloid leukemia: a case report [PDF]

Xin yixue, 2023
Blastic plasmacytoid dendritic cell neoplasm （BPDCN） complicated with acute myeloid leukemia （AML） is a rare disease. In this article， we reported the diagnosis and treatment of one patient of BPDCN complicated with AML who presented with fever as the ...
Kong Lihua, Qin Lili, Feng Anhua, Liu Zhenzhen, Tang Na, Zang Jikang, Wang Haiying
doaj   +1 more source