Results 81 to 90 of about 74,387 (246)

Chronic Overexpression of Bradykinin in Kidney Causes Polyuria and Cardiac Hypertrophy

open access: yesFrontiers in Medicine, 2018
Acute intra-renal infusion of bradykinin increases diuresis and natriuresis via inhibition of vasopressin activity. However, the consequences of chronically increased bradykinin in the kidneys have not yet been studied.
Carlos C. Barros   +21 more
doaj   +1 more source

Lisinopril-Induced Angioedema in a Patient with Plasma Prekallikrein Deficiency

open access: yesTH Open, 2020
Angiotensin-converting enzyme (ACE) inhibitors are extensively prescribed to treat patients with hypertension, congestive heart failure, and diabetic nephropathy.
Swapan K. Dasgupta   +2 more
doaj   +1 more source

Ca2+ transients are not required as signals for long-term neurite outgrowth from cultured sympathetic neurons [PDF]

open access: yes, 1990
A method for clamping cytosolic free Ca2+ ([Ca2+]i) in cultures of rat sympathetic neurons at or below resting levels for several days was devised to determine whether Ca2+ signals are required for neurite outgrowth from neurons that depend on Nerve ...
Murrell, R D   +3 more
core   +2 more sources

Research Progress on Upper Airway Cough Syndrome

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley   +1 more source

Development of an ex vivo model for the study of cerebrovascular function utilizing isolated mouse olfactory artery [PDF]

open access: yes, 2015
OBJECTIVE: Cerebral vessels, such as intracerebral perforating arterioles isolated from rat brain, have been widely used as an ex vivo model to study the cerebrovascular function associated with cerebrovascular disorders and the therapeutic effects of ...
Dietrich, Hans H.   +3 more
core   +2 more sources

International Guideline on the Diagnosis and Management of Pediatric Patients With Hereditary Angioedema

open access: yesAllergy, EarlyView.
ABSTRACT Hereditary angioedema (HAE) with C1 inhibitor deficiency is a rare disease characterized by unpredictable episodes of tissue swelling (angioedema), which, in most cases, occur first under the age of 18 years, and entail a significant burden of disease not only for the patients but also for their families.
Henriette Farkas   +128 more
wiley   +1 more source

PROTECTIVE EFFECT OF LIGNOCAINE AGAINST ACETYLCHOLINE AND BRADYKININ INDUCED TRACHEAL TISSUE CONTRACTION

open access: yesPakistan Armed Forces Medical Journal, 2019
Objective: To evaluate the protective effect of lignocaine against acetylcholine and bradykinin induced airway contraction of isolated tracheal tissue of guinea pig in vitro. Study Design: Laboratory based quasi experimental study.
Fatima Qasim Malik   +2 more
doaj  

Hereditary angioedema (HAE) in children and adolescents : a consensus on therapeutic strategies [PDF]

open access: yes, 2012
Hereditary angioedema due to C1 inhibitor (C1 esterase inhibitor) deficiency (types I and II HAE-C1-INH) is a rare disease that usually presents during childhood or adolescence with intermittent episodes of potentially life-threatening angioedema ...
Aberer, Werner   +11 more
core   +1 more source

The International Guideline for the Definition, Classification, Diagnosis and Management of Urticaria

open access: yesAllergy, EarlyView.
ABSTRACT This update and revision of the international guideline for urticaria was developed in accordance with the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is an initiative of the Global Allergy and Asthma Excellence Network (GA2LEN) and its Urticaria and ...
T. Zuberbier   +221 more
wiley   +1 more source

Direct Gαq Gating Is the Sole Mechanism for TRPM8 Inhibition Caused by Bradykinin Receptor Activation

open access: yesCell Reports, 2019
Summary: Activation of Gαq-coupled receptors by inflammatory mediators inhibits cold-sensing TRPM8 channels, aggravating pain and inflammation. Both Gαq and the downstream hydrolysis of phosphatidylinositol 4, 5-bisphosphate (PIP2) inhibit TRPM8. Here, I
Xuming Zhang
doaj   +1 more source

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