Results 101 to 110 of about 1,270,647 (242)

Function and structure of bradykinin receptor 2 for drug discovery. [PDF]

Acta Pharmacol Sin, 2023
Shen JK, Zhang HT.
europepmc   +1 more source

Eluate derived by extracorporal antibody-based immunoadsorption elevates the cytosolic Ca2+ concentration in podocytes via B-2 kinin receptors [PDF]

, 2002
Background/Aim: Patients with idiopathic focal segmental glomerulosclerosis (FSGS) often develop a recurrence of the disease after kidney transplantation.
Pavenstadt, H., Rump, L. C., Fischer, Karl-Georg, Pavenstädt, Hermann, Schwertfeger, E., Henger, Anna, Fischer, K. G., Rump, Lars Christian, Fink, E., Huber, Tobias B., Schwertfeger, Eckhard, Henger, A., Huber, T. B., Fink, Edwin   +13 more
core   +1 more source

TMEM16A channel signalling microdomains in the regulation of vascular function

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley   +1 more source

Evaluation and Management of Angioedema in the Emergency Department

Western Journal of Emergency Medicine, 2019
Angioedema is defined by non-dependent, non-pitting edema that affects several different sites and is potentially life-threatening due to laryngeal edema.
Brit Jeffrey Long, Alex Koyfman, Michael Gottlieb   +2 more
doaj   +1 more source

Raf kinase inhibitory protein reduces bradykinin receptor desensitization. [PDF]

J Neurochem, 2022
Chivers SB, Brackley AD, Jeske NA.
europepmc   +1 more source

Síntese de potenciais antagonistas do receptor B1 da bradicinina contendo o heterociclo piridazinona [PDF]

, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2013.Uma série de 4,5-di-hidro-3(2H)-piridazinonas dissubstituídas nas posições 4 e 6 do ...
Maximiano, Adrielle Patricio
core  

Induction of selective blood-tumor barrier permeability and macromolecular transport by a biostable kinin b1 receptor agonist in a glioma rat model [PDF]

, 2012
Treatment of malignant glioma with chemotherapy is limited mostly because of delivery impediment related to the blood-brain tumor barrier (BTB). B1 receptors (B1R), inducible prototypical G-protein coupled receptors (GPCR) can regulate permeability of ...
Neugebauer Witold, Audrey Fortier, Martin Savard (163526), David Fortin (163586), Tsanaclis Ana-Maria, Céléna Dubuc, Jérôme Côté (163514), Céléna Dubuc (163533), Audrey Fortier (163543), Dubuc Céléna, Gobeil, Fernand, Müller-Esterl Werner, Fortin David, Neugebauer, Witold, Werner Müller-Esterl, Gobeil Fernand, Martin Savard, Fortier, Audrey, Tsanaclis, Ana-Maria, Witold Neugebauer (163552), Fernand Gobeil, Tremblay Luc, Luc Tremblay (163561), Lepage, Martin, Veronica Bovenzi (163520), Müller-Esterl, Werner, Bovenzi Veronica, David Fortin, Jérôme Côté, Ana-Maria Tsanaclis, Martin Lepage (125474), Fernand Gobeil Jr (163594), Savard Martin, Fortier Audrey, Dubuc, Céléna, Tremblay, Luc, Lepage Martin, Côté, Jérôme, Luc Tremblay, Martin Lepage, Ana-Maria Tsanaclis (163574), Bovenzi, Veronica, Savard, Martin, Veronica Bovenzi, Côté Jérôme, Fortin, David, Werner Müller-Esterl (37090), Witold Neugebauer   +47 more
core   +2 more sources

Angiotensin‐converting enzyme and exercise adaptations: Genetic variability, pharmacological modulation and future directions

The Journal of Physiology, EarlyView.
Abstract figure legend ACE I/D genotype, enzyme activity and integrated physiological adaptations. Upper panel: Conceptual framework linking the ACE I/D polymorphism (left) with circulating/tissue ACE activity (centre; violin plots based on hypothetical data for illustration) and strength/power versus endurance phenotypes (right).
Tórur Sjúrðarson, Nikolai B. Nordsborg   +1 more
wiley   +1 more source

TheBDKRB2 +9/-9 Polymorphisms Influence Pro-Inflammatory Cytokine Levels in Knee Osteoarthritis by Altering TLR-2 Expression: Clinical and in Vitro Studies

Cellular Physiology and Biochemistry, 2016
Background/Aims: The bradykinin B2 receptor (BDKRB2) +9/-9 gene polymorphisms have been shown to be associated with the susceptibility and severity of osteoarthritis (OA); however, the underlying mechanisms are unclear. In this study, we investigated the
Shuo Chen, Lei Zhang, Ruonan Xu, Yunfan Ti, Yunlong Zhao, Liwu Zhou, Jianning Zhao   +6 more
doaj   +1 more source

Soluble CD13 induces inflammatory arthritis by activating the bradykinin receptor B1. [PDF]

J Clin Invest, 2022
Tsou PS, Lu C, Gurrea-Rubio M, Muraoka S, Campbell PL, Wu Q, Model EN, Lind ME, Vichaikul S, Mattichak MN, Brodie WD, Hervoso JL, Ory S, Amarista CI, Pervez R, Junginger L, Ali M, Hodish G, O'Mara MM, Ruth JH, Robida AM, Alt AJ, Zhang C, Urquhart AG, Lawton JN, Chung KC, Maerz T, Saunders TL, Groppi VE, Fox DA, Amin MA.   +30 more
europepmc   +1 more source