Results 101 to 110 of about 25,904 (219)

Effect of icatibant on sweating-induced dermal pain

Journal of Cutaneous Immunology and Allergy
BackgroundExposure to sweating stimuli triggers transient and severe dermal pain in certain individuals. This study aimed to evaluate the analgesic effect of icatibant, a bradykinin B2 receptor antagonist, for the dermal pain induced by sweating stimuli ...
Shunsuke Takahagi, Shunsuke Takahagi, Daiki Matsubara, Emi Murakami, Yumi Aoyama, Shinya Imamura, Atsushi Fukunaga, Atsushi Fukunaga, Yoshiko Oda, Hiroyuki Murota, Michihiro Hide, Michihiro Hide   +11 more
doaj   +1 more source

Involvement of Bradykinin Receptor 2 in Nerve Growth Factor Neuroprotective Activity. [PDF]

Cells, 2020
Petrella C, Ciotti MT, Nisticò R, Piccinin S, Calissano P, Capsoni S, Mercanti D, Cavallaro S, Possenti R, Severini C.   +9 more
europepmc   +1 more source

The chemokine receptor‐like fourth extracellular loop of the apelin receptor differentially regulates apelin and elabela binding and signalling

British Journal of Pharmacology, Volume 183, Issue 18, Page 5641-5656, September 2026.
Abstract Background and Purpose Apelin and Elabela are endogenous ligands of the apelin receptor (apelin receptor/APJ), a GPCR involved in cardiovascular regulation and body fluid homeostasis. The human receptor contains a conserved disulfide bridge linking the N‐terminal domain to extracellular loop 3 (ECL3) via Cys19 and Cys281, forming a structural ...
Chloé Bonef, Hela Bouhsine, Carine Huynh, Marion Chaigneau, Steven Dubois, Mikel Garcia‐Marcos, Catherine Llorens‐Cortes, Denis Servent, Philippe Robin, Hervé Nozach, Isabel Alves, Xavier Iturrioz   +11 more
wiley   +1 more source

Airway Intervention in Paediatric Angioedema: A National Analysis of Clinical Predictors and Outcomes

Clinical Otolaryngology, Volume 51, Issue 5, Page 729-735, September 2026.
ABSTRACT Objective To characterize paediatric hospitalizations for angioedema and identify the prevalence and outcomes of airway interventions using a large national database. Methods We performed a cross‐sectional analysis of the Kids' Inpatient Database (2003–2019), including paediatric patients (0–20 years) hospitalized with angioedema identified by
Saharsh Talwar, Aryan Mahajan, Gaurav N. Pathak, Babar K. Rao, Rachel Kaye   +4 more
wiley   +1 more source

On the History of Hepatic Vein Catheterization

Liver International, Volume 46, Issue 9, September 2026.
ABSTRACT Hepatic vein catheterization (HVC) in man was first performed 80 years ago in the wake of right‐sided heart catheterization. Several new methods, recognitions and concepts followed, especially the indirect Fick‐method for determination of splanchnic blood flow. Five years passed before pressure measurements were performed and routine HVCs were
Jens Henrik Henriksen, Flemming Bendtsen, Søren Møller   +2 more
wiley   +1 more source

Berotralstat Tolerability and Effectiveness in Hereditary Angioedema: Berolife Study Results

Clinical and Translational Allergy, Volume 16, Issue 8, August 2026.
ABSTRACT Background Berotralstat is a first‐line once‐daily oral prophylactic treatment for hereditary angioedema (HAE). Berolife was designed to evaluate the tolerability and effectiveness of berotralstat in real‐world conditions. Methods Berolife is an open‐label, multicenter, observational study conducted in France from September 2021 to January ...
Delphine Gobert, David Launay, Isabelle Boccon‐Gibod, Melisande Bourgoin‐Heck, Cyrille Hoarau, Yann Ollivier, Hervé Maillard, Fabien Pontille, Nicolas Ozanne, Magali Aubineau, Claire de Moreuil, Anne Gerber, Fabien Pelletier, Pierre‐Yves Jeandel, Aurélie Du‐Thanh, Marie‐Caroline Dalmas, Marie‐Caroline Taquet, Jean Schmidt, Amélie Servettaz, Amandine Perier, Enzo Cohen, Laure Carriat, Nicolas Lemaire, Mona Villedieu, Jean‐Charles Crave, Olivier Fain, Laurence Bouillet   +26 more
wiley   +1 more source

Bradykinin Receptor B1 and C-Reactive Protein as Prognostic Factors for Pharyngocutaneous Fistula Development After Laryngectomy. [PDF]

Head Neck Pathol, 2020
Koob I, Pickhard A, Buchberger M, Boxberg M, Reiter R, Piontek G, Straßen U.   +6 more
europepmc   +1 more source

The Effects of Bromelain Supplementation on Clinical Outcomes, Inflammatory and Oxidative Stress Biomarkers in Patients With Traumatic Brain Injury: A Randomized, Double‐Blind Placebo‐Controlled Clinical Trial

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Bromelain supplementation significantly reduced IL‐6 levels (p < 0.001), APACHE scores (p = 0.011), SOFA scores (p < 0.001), and NUTRIC scores (p < 0.001). Furthermore, 60‐day mortality was significantly lower in the Bromelain group compared to the Placebo group (p = 0.036). However, there was no significant effect on CRP (p = 0.377) or MDA levels (p = 
Alireza Gheflati, Mohammad Rashid Mayvan, Mojgan Mehri Ardestani, Seyed Mahdi Mirghazanfari, Ebrahim Hazrati, Mohamad Shahab Kalantar, Vahid Hadi, Ali Jafarzadeh Esfehani, Saeid Hadi   +8 more
wiley   +1 more source

Pharmacological Assessment of Calamus guruba Methanolic Extract: Multitarget Effects on Diabetes, Inflammation, Anxiety, and Depression

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Calamus guruba Buch.‐Ham. (family Arecaceae) is a highly regarded traditional medicinal plant known for its diverse therapeutic benefits. This research aimed to investigate the antidiabetic, anti‐inflammatory, anxiolytic, and antidepressant effects of the methanolic extract of C. guruba (MECG).
Mohi Uddin, Tania Akter Shorna, Khurshida Jahan Suma, Md. Ekramul Haque Ekram, Masud Rana, Md. Jahirul Islam Mamun   +5 more
wiley   +1 more source

Integrative GC–MS, FT‐IR, and Molecular Docking Analysis of Drimycarpus racemosus (Roxb.) Hook.f ex Marchand: In Vivo Analgesic and Antidiabetic Potential

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
GC–MS profiling of D. racemosus identified bioactive phytochemicals with promising molecular interactions through docking analysis. The methanolic extract demonstrated significant antinociceptive activity against acetic acid‐ and formalin‐induced pain and exhibited antidiabetic effects in streptozotocin‐induced diabetic Swiss albino mice, supporting ...
Md Sajib Ali, Md. Rakibul Islam, M. A. Rafi, Sanjana Haque Esha, Md. Mehedi Hasan, Payar Hossain, Abdullah Ripon, Nilufar Sultana   +7 more
wiley   +1 more source