Results 21 to 30 of about 25,904 (219)

Assembly of Bioactive Superstructures via Metal–Phenolic Complexation for Blood Purification

Angewandte Chemie, EarlyView.
Bioactive superstructures are assembled via metal–phenolic‐mediated assembly on agarose templates, followed by modification with human serum albumin. These superstructures demonstrate high bilirubin adsorption efficiency, strong antibacterial activity, and anticoagulant activity, providing a strategy for the rational design of multifunctional blood ...
Po Wang, Jingqu Chen, Siying Chen, Binsha Peng, Zhifeng Zhou, Ling Zhang, Rui Xie, Xiaojie Ju, Wei Wang, Dawei Pan, Liangyin Chu, Frank Caruso, Zhuang Liu   +12 more
wiley   +2 more sources

The Pathophysiology of Hereditary Angioedema

World Allergy Organization Journal, 2010
Hereditary angioedema (HAE) causes recurrent episodes of angioedema that may be very severe and are frequently associated with significant morbidity and even mortality. Understanding the pathophysiology of this disease is crucial for proper diagnosis and
Bruce L Zuraw, MD
doaj   +1 more source

Metabolically stable bradykinin B2 receptor agonists enhance transvascular drug delivery into malignant brain tumors by increasing drug half-life

Journal of Translational Medicine, 2009
Background The intravenous co-infusion of labradimil, a metabolically stable bradykinin B2 receptor agonist, has been shown to temporarily enhance the transvascular delivery of small chemotherapy drugs, such as carboplatin, across the blood-brain tumor ...
Glen Daniel, Cox Robert W, Butman John A, Fung Steve H, Kanevsky Ariel S, Sarin Hemant, Reynolds Richard, Auh Sungyoung   +7 more
doaj   +1 more source

Increased plasma bradykinin level is associated with cognitive impairment in Alzheimer's patients

Neurobiology of Disease, 2020
Alzheimer's disease (AD) is characterized by the presence of proteinaceous brain deposits, brain atrophy, vascular dysfunction, and chronic inflammation.
Pradeep K. Singh, Zu-Lin Chen, Dhiman Ghosh, Sidney Strickland, Erin H. Norris   +4 more
doaj   +1 more source

Drug-induced visceral angioedema [PDF]

Journal of Community Hospital Internal Medicine Perspectives, 2014
Angioedema associated with angiotensin converting enzyme inhibitors (ACEIs) is due to the accumulation of bradykinin and its metabolites. Angiotensin receptor blockers (ARBs) produce anti-hypertensive effects by blocking the angiotensin II AT1 receptor ...
Prashanth M. Thalanayar, Ibrahim Ghobrial, Fritz Lubin, Reena Karnik, Robin Bhasin   +4 more
doaj   +1 more source

ACE2/ACE imbalance mediates bisphenol A-induced lung injury in Wistar rats: Results from captopril versus losartan histo-biochemical study

Heliyon, 2023
Bisphenol-A (BPA) is a synthetic chemical compound broadly used in the plastic and epoxy resin industries with a considerable potential for food contamination. Literary reports have suggested that the altered renin-angiotensin system (RAS) is a mechanism
Ahmed A. Morsi, Ezat A. Mersal, Ahmed M. Abdelmoneim, Eman Mohamed Faruk, Mohamed M. Sofii, Nehad Ahmed Sadek, Khalid Elfaki Ibrahim, Hatem J. Aljanfawe, Iman Elmadhoun, Wejdan Mubarak, Mashael Malik Mahmoud, Mohamed S. Salim   +11 more
doaj   +1 more source

Bradykinin B2 receptor blockade and intradialytic hypotension

BMC Nephrology, 2023
Introduction Intradialytic hypotension (IDH) is a common clinical complication and is associated with increased morbidity and mortality in patients undergoing maintenance hemodialysis (MHD).
Jorge L. Gamboa, Cindy A. Mambungu, Adrienne R. Clagett, Hui Nian, Chang Yu, T. Alp Ikizler, Nancy J. Brown   +6 more
doaj   +1 more source

Relaxant Effect of Prostaglandin D2–Receptor DP Agonist on Liver Myofibroblast Contraction

Journal of Pharmacological Sciences, 2011
.: Increased intrahepatic resistance causes portal hypertension in cirrhosis. Liver myofibroblasts (MFs) are now regarded as the principle cells involved in sinusoidal blood flow regulation.
Tomoharu Maruyama, Shinya Ayabe, Takahisa Murata, Masatoshi Hori, Hiroshi Ozaki   +4 more
doaj   +1 more source

Bradykinin increases resensitization of purinergic receptor signaling in glioma cells

Cancer Cell International, 2010
Background Purinergic receptor-mediated signaling plays an important role in the function of glial cells, including glial tumor cells. Bradykinin is also an important paracrine mediator which is highly expressed in brain tumors and may correlate with ...
Brennan Kevin C, Beltran-Parrazal Luis, López-Valdés Héctor E, Charles Andrew C   +3 more
doaj   +1 more source

Can’t Intubate, Can’t Oxygenate: A Rare Case of a Difficult Airway due to Nonhereditary Angioedema

Acta Clinica Croatica, 2022
Angioedema is a form of allergic mediated by histamine and non-allergic mediated by bradykinin and can be lethal if not recognized and treated promptly.
Điđi Delalić, Vinko Borčić, Ingrid Prkačin   +2 more
doaj   +1 more source