Results 111 to 120 of about 119,295 (311)

KRAS and BRAF mutations in Iranian colorectal cancer patients: A systematic review and meta-analysis

open access: yesCaspian Journal of Internal Medicine, 2020
Background: Mutations in the EGFR signaling pathway play an important role in the development of colorectal cancer (CRC). Mutations in these genes, like KRAS and BRAF, affect the treatment strategies and associated with poor prognosis and relative ...
Abolfazl Yari   +4 more
doaj  

The Role and Importance of Molecular Tests in Approach to Thyroid Nodules

open access: yesTurkish Archives of Otorhinolaryngology, 2016
Although there is a significant increase in the detection of thyroid cancer because of the widespread utilization of ultrasound and fine needle aspiration biopsy, sometimes these techniques prove inefficient for diagnosis.
Levent Gürbüzler
doaj   +1 more source

Molecular genetic analysis of paediatric low-grade astrocytoma [PDF]

open access: yes, 2010
The thesis describes the molecular genetic analysis of fifty low-grade paediatric astrocytomas. DNA copy number changes were investigated in paediatric low-grade astrocytomas (WHO grade I and II), using array comparative genomic hybridisation and ...
Tatevossian, R.G.
core  

Correlations CAT with BRAF-MDQ, BRAF-NRS and SF-36.

open access: yes, 2016
Correlations CAT with BRAF-MDQ, BRAF-NRS and SF-36.
Christina Bode (841595)   +5 more
core   +1 more source

Two Pillars of My Path in Cytopathology: Mentorship From Training to Practice

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Mentorship has been a cornerstone of my professional development in cytopathology, shaping both my diagnostic acumen and academic identity. Under the guidance of Dr. Claire Michael during residency and fellowship, I was introduced to a culture of intellectual rigor, systems thinking, and continuous improvement.
Hamza N. Gokozan
wiley   +1 more source

BRAF mutation screening in melanoma

open access: yes, 2015
International audienceAs the detection of the BRAF V600E mutation has a direct impact on treatment decision, an accurate screening for BRAF mutations in patients with advanced or metastatic melanoma is mandatory.
Aubin, François   +7 more
core   +1 more source

Low‐Grade Serous Carcinoma in Association With Endosalpingiosis in a Cervical Lymph Node: A Case Report and Literature Review

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Endosalpingiosis is a benign Müllerian inclusion that rarely involves supradiaphragmatic lymph nodes. Malignant transformation in the setting of nodal endosalpingiosis is exceptional. We report a case of low‐grade serous carcinoma arising in a cervical lymph node in the setting of endosalpingiosis in a 41‐year‐old woman presenting with Horner ...
Nyein Nyein Htun, Nour Sneige
wiley   +1 more source

Molecular Pathways: Response and Resistance to BRAF and MEK Inhibitors in BRAF(V600E) Tumors

open access: yes, 2014
The RAS-RAF-MEK (MAP-ERK kinase)-ERK (extracellular signal-regulated kinase) pathway plays a central role in driving proliferation, survival, and metastasis signals in tumor cells, and the prevalence of oncogenic mutations in RAS and BRAF and upstream ...
Stuart, DD, Das Thakur, M
core  

Mascot search result for BRAF mutated vs BRAF wt patients.

open access: yes, 2014
Mascot search result for BRAF mutated vs BRAF wt patients.
Simona De Summa (667535)   +8 more
core   +1 more source

Concomitant KIT/BRAF and PDGFRA/BRAF mutations are rare events in gastrointestinal stromal tumors [PDF]

open access: yes, 2016
AIM: The BRAF mutation is a rare pathogenetic alternative to KIT/PDGFRA mutation in GIST and causes Imatinib resistance. A recent description of KIT and BRAF mutations co-occurring in an untreated GIST has challenged the concept of their being mutually ...
Mandolesi, Alessandra   +19 more
core   +1 more source

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