Results 31 to 40 of about 12,470,437 (381)
Emerging Roles of Astrocyte Kir4.1 Channels in the Pathogenesis and Treatment of Brain Diseases
International Journal of Molecular Sciences, 2021 Inwardly rectifying Kir4.1 channels in astrocytes mediate spatial potassium (K+) buffering, a clearance mechanism for excessive extracellular K+, in tripartite synapses.
Y. Ohno, Naofumi Kunisawa, S. Shimizu
semanticscholar +1 more source
Quantitative Imaging in Medicine and Surgery, 2021 Photoacoustic imaging (PAI) is an emerging imaging strategy with a unique combination of rich optical contrasts, high ultrasound spatial resolution, and deep penetration depth without ionizing radiation.
Ting Qiu +9 more
semanticscholar +1 more source
Development of Novel Therapeutics Targeting the Blood–Brain Barrier: From Barrier to Carrier
Advanced Science, 2021 The blood–brain barrier (BBB) is a highly specialized neurovascular unit, initially described as an intact barrier to prevent toxins, pathogens, and potentially harmful substances from entering the brain.
Jia Li +6 more
doaj +1 more source
European Journal of Psychotraumatology, 2023 Background: Posttraumatic stress disorder (PTSD) is prevalent in people with acquired brain injury (ABI). Despite the established efficacy of eye movement desensitization and reprocessing (EMDR) for PTSD in general, evaluation studies on EMDR in ABI ...
E.P.J. Janssen +3 more
doaj +1 more source
New Promising Therapeutic Avenues of Curcumin in Brain Diseases
Molecules, 2021 Curcumin, the dietary polyphenol isolated from Curcuma longa (turmeric), is commonly used as an herb and spice worldwide. Because of its bio-pharmacological effects curcumin is also called “spice of life”, in fact it is recognized that curcumin possesses
T. Benameur +9 more
semanticscholar +1 more source
High-Throughput Screening Platforms in the Discovery of Novel Drugs for Neurodegenerative Diseases
Bioengineering, 2021 Neurodegenerative diseases (NDDs) are incurable and debilitating conditions that result in progressive degeneration and/or death of nerve cells in the central nervous system (CNS).
Hasan Aldewachi +3 more
doaj +1 more source
Validation of Induced Microglia-Like Cells (iMG Cells) for Future Studies of Brain Diseases
Frontiers in Cellular Neuroscience, 2021 Microglia are the primary resident immune cells of the central nervous system that maintain physiological homeostasis in the brain and contribute to the pathogenesis of many psychiatric disorders and neurodegenerative diseases.
A. Banerjee +6 more
semanticscholar +1 more source
Is Alzheimer’s Disease a Liver Disease of the Brain? [PDF]
Journal of Alzheimer's Disease, 2020 Clinical specialization is not only a force for progress, but it has also led to the fragmentation of medical knowledge. The focus of research in the field of Alzheimer's disease (AD) is neurobiology, while hepatologists focus on liver diseases and lipid specialists on atherosclerosis.
Margaret Bassendine +6 more
openaire +5 more sources
Aquaporin and brain diseases [PDF]
Biochimica et Biophysica Acta (BBA) - General Subjects, 2014 The presence of water channel proteins, aquaporins (AQPs), in the brain led to intense research in understanding the underlying roles of each of them under normal conditions and pathological conditions.In this review, we summarize some of the recent knowledge on the 3 main AQPs (AQP1, AQP4 and AQP9), with a special focus on AQP4, the most abundant AQP ...
Klaus G. Petry +4 more
openaire +3 more sources
Neuroinflammation and Its Resolution: From Molecular Mechanisms to Therapeutic Perspectives [PDF]
, 2020 Neuroinflammation, the complex immune response of the central nervous system (CNS), when sustained, is a common denominator in the etiology and course of all major neurological diseases, including neurodevelopmental, neurodegenerative, and psychiatric ...
Berwian +11 more
core +2 more sources