Results 31 to 40 of about 12,998,191 (376)
Frontiers in Nutrition, 2022 Research to date has provided novel insights into lactate's positive role in multiple brain functions and several brain diseases. Although notable controversies and discrepancies remain, the neurobiological role and the metabolic mechanisms of brain ...
Ming Cai +7 more
semanticscholar +1 more source
Development of Novel Therapeutics Targeting the Blood–Brain Barrier: From Barrier to Carrier
Advanced Science, 2021 The blood–brain barrier (BBB) is a highly specialized neurovascular unit, initially described as an intact barrier to prevent toxins, pathogens, and potentially harmful substances from entering the brain.
Jia Li +6 more
doaj +1 more source
European Journal of Psychotraumatology, 2023 Background: Posttraumatic stress disorder (PTSD) is prevalent in people with acquired brain injury (ABI). Despite the established efficacy of eye movement desensitization and reprocessing (EMDR) for PTSD in general, evaluation studies on EMDR in ABI ...
E.P.J. Janssen +3 more
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Applications of nanobodies in brain diseases
Frontiers in Immunology, 2022 Nanobodies are antibody fragments derived from camelids, naturally endowed with properties like low molecular weight, high affinity and low immunogenicity, which contribute to their effective use as research tools, but also as diagnostic and therapeutic ...
Fang Zheng +6 more
semanticscholar +1 more source
High-Throughput Screening Platforms in the Discovery of Novel Drugs for Neurodegenerative Diseases
Bioengineering, 2021 Neurodegenerative diseases (NDDs) are incurable and debilitating conditions that result in progressive degeneration and/or death of nerve cells in the central nervous system (CNS).
Hasan Aldewachi +3 more
doaj +1 more source
Detrimental Roles of Hypoxia-Inducible Factor-1α in Severe Hypoxic Brain Diseases. [PDF]
Int J Mol SciHypoxia stabilizes hypoxia-inducible factors (HIFs), facilitating adaptation to hypoxic conditions. Appropriate hypoxia is pivotal for neurovascular regeneration and immune cell mobilization. However, in central nervous system (CNS) injury, prolonged and
Choi YK.
europepmc +2 more sources
Alzheimer and vascular brain diseases: Focal and diffuse subforms. [PDF]
, 2015 Alois Alzheimer is best known for his description of the pre-senile neurodegenerative disease named after him. However, his previous interest in vascular brain diseases, underlying cognitive and behavioral changes, was very strong. Besides describing the
Engelhardt, Eliasz, Grinberg, Lea T
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Quinidine in Treatment of Migrating Partial Seizures of Infancy
Pediatric Neurology Briefs, 2014 Investigators at Children's Hospital of Philadelphia, PA, report a 3-year-old female who had presented with seizures at 10 weeks of life.
J Gordon Millichap, John J Millichap
doaj +1 more source
The Role of the Thioredoxin System in Brain Diseases
Antioxidants, 2022 The thioredoxin system, consisting of thioredoxin (Trx), thioredoxin reductase (TrxR), and NADPH, plays a fundamental role in the control of antioxidant defenses, cell proliferation, redox states, and apoptosis.
Geir Bjørklund +6 more
semanticscholar +1 more source
Drug delivery in overcoming the blood-brain barrier: role of nasal mucosal grafting [PDF]
, 2017 The blood–brain barrier (BBB) plays a fundamental role in protecting and maintaining the homeostasis of the brain. For this reason, drug delivery to the brain is much more difficult than that to other compartments of the body. In order to bypass or cross
Carafa, Maria +5 more
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