Results 101 to 110 of about 268,974 (335)

A Novel Cranial Bone Transport Technique Repairs Skull Defect and Minimizes Brain Injury Outcome in Traumatic Brain Injury Rats

Advanced Science, EarlyView.
This study introduces a novel, safe, and effective surgical technique: Cranial bone transport (CBT) to improve traumatic brain injury (TBI) outcomes in rats. CBT significantly accelerated skull defect bone repair in addition to its promoting effects on neurological function recovery. This work provides an alternative therapy for patients suffering from
Shanshan Bai, Xuan Lu, Xu Yan, Han Su, Yuejun Lin, Zhaowei Jiang, Zhixian Zong, Haixing Wang, Leo Yik Chun Yan, Xiaoting Zhang, Ming Wang, Zhengmeng Yang, Jiakang Jin, Yaofeng Wang, Wayne Yuk‐Wai Lee, Xiaohua Jiang, Ho Ko, Lu Feng, Micky D. Tortorella, Sien Lin, Gang Li   +20 more
wiley   +1 more source

Treadmill exercise decreases cerebral edema in rats with local cerebral infarction by modulating AQP4 polar expression through the caveolin-1/TRPV4 signaling pathway

Brain Research Bulletin, 2022
Rehabilitation therapy is beneficial for patients with ischemic stroke. Our previous study showed that treadmill training is conducive to neurological function in rats that underwent middle cerebral artery occlusion (MCAO).
Anqi Zhu, Yao Lin, Xuanbo Hu, Zaizai Lin, Yongqiang Lin, Qingfeng Xie, Shaobo Ni, Hui Cheng, Qiaoya Lu, Shanshan Lai, Guoyuan Pan, Xiang Chen, Wei Pang, Chan Liu   +13 more
doaj  

Peritumoral edema at brain meningiomas

Acta Biomedica Scientifica, 2016
Among edema-producing neoplasms of central neural system, the meningiomas are unique. Meningiomas are histologically benign, slow growing and originate extracerebrally.
V. A. Byvaltsev, V. A. Sorokovikov, E. B. Borisov, I. A. Stepanov   +3 more
doaj   +1 more source

Rapamycin Alleviates Heart Failure Caused by Mitochondrial Dysfunction and SERCA Hypoactivity in Syntaxin 12/13 Deficient Models

Advanced Science, EarlyView.
Rapamycin alleviates heart failure via TFEB and CaMKII pathways in Syntaxin 12/13 deficient models. Stx12 deficiency causes heart failure via impaired iron trafficking to mitochondria, reducing respiratory complexes and sarcoplasmic reticulum Ca2+‐ATPase (SERCA).
Run‐Zhou Yang, Fang Li, Jiao Liu, Shu‐Ang Li, Dan‐Hua Liu, Zhuanbin Wu, Pei‐Pei Liu, Wenju Liu, Bin Zhou, Cizhong Jiang, Haibing Zhang, Ying Yu, Jian‐Sheng Kang   +12 more
wiley   +1 more source

Acute symptomatic peri-lead edema 33 hours after deep brain stimulation surgery: a case report

Journal of Medical Case Reports, 2017
Background Symptomatic peri-lead edema is a rare complication of deep brain stimulation that has been reported to develop 4 to 120 days postoperatively.
Nathan B. Schoen, Walter J. Jermakowicz, Corneliu C. Luca, Jonathan R. Jagid   +3 more
doaj   +1 more source

EDEMA OF THE OPTIC DISK IN BRAIN INJURY [PDF]

, 1919
E Klauber
openalex   +1 more source

Astrocytic ET‐1 System Determines Microglia Phenotype Following Spinal Cord Injury

Advanced Science, EarlyView.
The study reveals that astrocytic ET‐1 system is solely activated by thrombin following SCI via RhoA/NF‐κB and MAPKs/NF‐κB signal pathway. The release of astrocytic ET‐1 drives microglia polarization toward M1 phenotype through YAP signaling via ETA and ETB receptors.
Bingqiang He, Si Xu, Mengdi Li, Hui Li, Shaolan Li, Li Niu, Honghua Song, Rixin Cai, Yue Zhou, Zhilong Cao, Yingjie Wang, Yongjun Wang   +11 more
wiley   +1 more source

Effect of fenofibrate on brain infarction, brain swelling and edema in focal-transient cerebral ischemia in rat

مجله علمی دانشگاه علوم پزشکی کردستان, 2021
Background and Aim: Increasing evidence has demonstrated that activation of peroxisome proliferator-activated receptor alpha (PPARα), which belongs to the nuclear receptor family of ligand-activated transcription factors, after cerebral ischemia exhibit ...
Hadi Vahidi, Shima Shahyad, Ali Noroozzadeh, Mohammad Taghi Mohammadi   +3 more
doaj  

Solving the Amyloid Paradox: Unveiling the Complex Pathogenicity of Amyloid Fibrils

Aggregate, EarlyView.
This review addresses the gap between strong evidence for the involvement of amyloid fibrils in neurodegeneration and the failure of anti‐amyloid therapies, a phenomenon herein termed the “amyloid paradox.” To address this paradox, we provide a comprehensive summary of the current understanding of fibrils' pathogenic properties and mechanisms ...
Maksim I. Sulatsky, Olesya V. Stepanenko, Olga V. Stepanenko, Anna I. Sulatskaya   +3 more
wiley   +1 more source

Assessing Large Multimodal Models for One‐Shot Learning and Interpretability in Biomedical Image Classification

Advanced Intelligent Systems, EarlyView.
Image classification plays a pivotal role in biomedical image analysis. Herein, it is shown that large multimodal models, such as GPT‐4, achieve superior performance in one‐shot learning, generalization, interpretability, and text‐driven image classification. Applications span tissue, cell type, cellular state, and disease classification, outperforming
Wenpin Hou, Qi Liu, Huifang Ma, Yilong Qu, Zhicheng Ji   +4 more
wiley   +1 more source