Brain Ischemia as a Prelude to Alzheimer's Disease
Frontiers in Aging Neuroscience, 2021 Transient ischemic brain injury causes massive neuronal death in the hippocampus of both humans and animals. This was accompanied by progressive atrophy of the hippocampus, brain cortex, and white matter lesions.
Ryszard Pluta +2 more
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Transplantation of human neural stem/progenitor cells overexpressing galectin-1 improves functional recovery from focal brain ischemia in the mongolian gerbil [PDF]
Molecular Brain, 2011 Transplantation of human neural stem/progenitor cells (hNSPCs) is a promising method to regenerate tissue from damage and recover function in various neurological diseases including brain ischemia.
Yamane Junichi +10 more
doaj +5 more sources
Neuroprotective effects of crocin on the histopathological alterations following brain ischemia-reperfusion injury in rat [PDF]
Iranian Journal of Basic Medical Sciences, 2014 Objective(s): Some histopathological alterations take place in the ischemic regions following brain ischemia. Recent studies have demonstrated some neuroprotective roles of crocin in different models of experimental cerebral ischemia.
Javad Raouf Sarshoori +2 more
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Glial activation in white matter following ischemia in the neonatal P7 rat brain [PDF]
arXiv, 2006 This study examines cell death and proliferation in the white matter after neonatal stroke. In post-natal day 7 injured rat, there was a marked reduction in myelin basic protein (MBP) immunostaining mainly corresponding to numerous pyknotic immature oligodendrocytes and TUNEL-positive astrocytes in the ipsilateral external capsule.
Biran, Valérie +7 more
arxiv +5 more sources
Calcium Fluxes, Calcium Antagonists, and Calcium-Related Pathology in Brain Ischemia, Hypoglycemia, and Spreading Depression: A Unifying Hypothesis [PDF]
Journal of Cerebral Blood Flow and Metabolism, 1989 Bo K. Siesjö, Finn Bengtsson
openalex +2 more sources
Roles of Nitric Oxide in Brain Ischemia and Reperfusion
International Journal of Molecular Sciences, 2022 Brain ischemia and reperfusion (I/R) is one of the most severe clinical manifestations of ischemic stroke, placing a significant burden on both individuals and society.
Yijie Wang, Fenfang Hong, Shulong Yang
semanticscholar +1 more source
Glial Cells as Therapeutic Approaches in Brain Ischemia-Reperfusion Injury
Cells, 2021 Ischemic stroke is the second cause of mortality and the first cause of long-term disability constituting a serious socioeconomic burden worldwide.
Ivó H Hernández +4 more
semanticscholar +1 more source
PLoS ONE, 2021 This study was the first to compare the neuroprotective activity of Cerebrolysin®, Actovegin® and Cortexin® in rodent models of acute and chronic brain ischemia.
D. V. Kurkin +12 more
semanticscholar +1 more source
Association of Cerebral Ischemia With Corneal Nerve Loss and Brain Atrophy in MCI and Dementia
Frontiers in Neuroscience, 2021 IntroductionThis study assessed the association of cerebral ischemia with neurodegeneration in mild cognitive impairment (MCI) and dementia.MethodsSubjects with MCI, dementia and controls underwent assessment of cognitive function, severity of brain ...
Georgios Ponirakis +30 more
doaj +1 more source
Frontiers in Physiology, 2020 Oxidative stress and inflammation are two critical pathological processes of cerebral ischemia-reperfusion injury. Myeloperoxidase (MPO) is a critical inflammatory enzyme and therapeutic target triggering both oxidative stress and neuroinflammation in ...
Shuang Chen +3 more
semanticscholar +1 more source