Results 1 to 10 of about 2,811,049 (348)
Brain Ischemia as a Prelude to Alzheimer's Disease
Frontiers in Aging Neuroscience, 2021 Transient ischemic brain injury causes massive neuronal death in the hippocampus of both humans and animals. This was accompanied by progressive atrophy of the hippocampus, brain cortex, and white matter lesions.
Ryszard Pluta +2 more
doaj +2 more sources
Roles of Nitric Oxide in Brain Ischemia and Reperfusion. [PDF]
Int J Mol Sci, 2022 Brain ischemia and reperfusion (I/R) is one of the most severe clinical manifestations of ischemic stroke, placing a significant burden on both individuals and society.
Wang Y, Hong F, Yang S.
europepmc +2 more sources
Association of Cerebral Ischemia With Corneal Nerve Loss and Brain Atrophy in MCI and Dementia [PDF]
Frontiers in Neuroscience, 2021 IntroductionThis study assessed the association of cerebral ischemia with neurodegeneration in mild cognitive impairment (MCI) and dementia.MethodsSubjects with MCI, dementia and controls underwent assessment of cognitive function, severity of brain ...
Georgios Ponirakis +30 more
doaj +2 more sources
Amyloid pathology in the brain after ischemia
Folia Neuropathologica, 2019 As the population is aging all over the world, the economic burden of ischemic brain injuries is constantly increasing. Human brain ischemia is one of the leading causes of premature death, significant morbidity and physical and mental disabilities ...
Ryszard Pluta +3 more
doaj +2 more sources
Neuroprotective effects of crocin on the histopathological alterations following brain ischemia-reperfusion injury in rat [PDF]
Iranian Journal of Basic Medical Sciences, 2014 Objective(s): Some histopathological alterations take place in the ischemic regions following brain ischemia. Recent studies have demonstrated some neuroprotective roles of crocin in different models of experimental cerebral ischemia.
Javad Raouf Sarshoori +2 more
doaj +2 more sources
Microbiome, 2023 Background Aging is a significant risk factor for ischemic stroke and worsens its outcome. However, the mechanisms for this worsened neurological outcome with aging are not clearly defined.
Xianzhang Zeng +4 more
semanticscholar +1 more source
pH and proton-sensitive receptors in brain ischemia
Journal of Cerebral Blood Flow and Metabolism, 2022 Extracellular proton concentration is at 40 nM when pH is 7.4. In disease conditions such as brain ischemia, proton concentration can reach µM range.
Xiang-ming Zha, Z. Xiong, R. Simon
semanticscholar +1 more source
Glial Cells as Therapeutic Approaches in Brain Ischemia-Reperfusion Injury
Cells, 2021 Ischemic stroke is the second cause of mortality and the first cause of long-term disability constituting a serious socioeconomic burden worldwide.
Ivó H Hernández +4 more
semanticscholar +1 more source
PLoS ONE, 2021 This study was the first to compare the neuroprotective activity of Cerebrolysin®, Actovegin® and Cortexin® in rodent models of acute and chronic brain ischemia.
D. V. Kurkin +12 more
semanticscholar +1 more source
Intravenous tPA therapy does not worsen acute intracerebral hemorrhage in mice [PDF]
, 2013 Tissue plasminogen activator (tPA) is the only FDA-approved treatment for reperfusing ischemic strokes. But widespread use of tPA is still limited by fears of inadvertently administering tPA in patients with intracerebral hemorrhage (ICH).
Arai, Ken +13 more
core +14 more sources