Transplantation of human neural stem/progenitor cells overexpressing galectin-1 improves functional recovery from focal brain ischemia in the mongolian gerbil [PDF]
Transplantation of human neural stem/progenitor cells (hNSPCs) is a promising method to regenerate tissue from damage and recover function in various neurological diseases including brain ischemia.
Yamane Junichi+10 more
doaj +5 more sources
Disruption of the Serotonergic System after Neonatal Hypoxia-Ischemia in a Rodent Model [PDF]
Identifying which specific neuronal phenotypes are vulnerable to neonatal hypoxia-ischemia, where in the brain they are damaged, and the mechanisms that produce neuronal losses are critical to determine the anatomical substrates responsible for ...
Kathryn M. Buller+2 more
doaj +4 more sources
Brain Ischemia as a Prelude to Alzheimer's Disease [PDF]
Transient ischemic brain injury causes massive neuronal death in the hippocampus of both humans and animals. This was accompanied by progressive atrophy of the hippocampus, brain cortex, and white matter lesions.
Ryszard Pluta+2 more
doaj +4 more sources
To the problems of modeling the brain ischemia in small animals [PDF]
In the review article the problems of modeling cerebral ischemia in small mammals are consecrated. The advantages of experimental studies that are based on the similarity of the blood circulation of the brain in humans and animals are indicated ...
A. N. Stoyanov+5 more
doaj +6 more sources
Cognitive function restoration in rats with chronic brain ischemia using Semax and hopantenic acid comprehensive administration [PDF]
The relevance and importance of treating patients with ischemic brain lesions are indisputable. Chronic ischemic processes in the brain occur much more frequently than acute cerebral circulation disorders, leading to prolonged disability and being the ...
V. Kirchev
doaj +3 more sources
Muscle activity and emotional behavior changes in rats with chronic brain ischemia via comprehensive pathogenetic correction [PDF]
Cerebrovascular pathology has evolved from a medical concern to a social issue, with the efficacy of secondary neuroprotection remaining a pertinent question.
V. Kirchev
doaj +3 more sources
Glial activation in white matter following ischemia in the neonatal P7 rat brain [PDF]
This study examines cell death and proliferation in the white matter after neonatal stroke. In post-natal day 7 injured rat, there was a marked reduction in myelin basic protein (MBP) immunostaining mainly corresponding to numerous pyknotic immature oligodendrocytes and TUNEL-positive astrocytes in the ipsilateral external capsule.
Biran, Valérie+7 more
arxiv +5 more sources
A Program for Solving the Brain Ischemia Problem [PDF]
Our recently described nonlinear dynamical model of cell injury is here applied to the problems of brain ischemia and neuroprotection. We discuss measurement of global brain ischemia injury dynamics by time course analysis.
Donald J. DeGracia
doaj +4 more sources
Amyloid pathology in the brain after ischemia
As the population is aging all over the world, the economic burden of ischemic brain injuries is constantly increasing. Human brain ischemia is one of the leading causes of premature death, significant morbidity and physical and mental disabilities ...
Ryszard Pluta+3 more
doaj +3 more sources
Brain ischemia as a bridge to Alzheimer's disease. [PDF]
Pluta R.
europepmc +5 more sources