Results 1 to 10 of about 210,266 (266)

Association of Cerebral Ischemia With Corneal Nerve Loss and Brain Atrophy in MCI and Dementia

open access: yesFrontiers in Neuroscience, 2021
IntroductionThis study assessed the association of cerebral ischemia with neurodegeneration in mild cognitive impairment (MCI) and dementia.MethodsSubjects with MCI, dementia and controls underwent assessment of cognitive function, severity of brain ...
Georgios Ponirakis   +30 more
doaj   +1 more source

Propofol Pretreatment Protects Hippocampal CA1 Neurons from Ischemia-reperfusion Injury in Rat

open access: yesOtorhinolaryngology and Facial Plastic Surgery, 2023
Background: The number of brain strokes induced by ischemia has increased significantly in recent years as a result of brain vascular disorders. Some of these patients will require brain vascular surgery.
Delaram Farhangi   +3 more
doaj   +1 more source

Top ten discoveries of the year: Neurovascular disease

open access: yesFree Neuropathology, 2020
The aim of this review is to highlight novel findings in 2019 in the area of neurovascular disease. Experimental studies have provided insight into disease development, molecular determinants of pathology, and putative novel therapeutic targets.
Anna Maria Planas
doaj   +1 more source

Dendritic Cells and Microglia Have Non-redundant Functions in the Inflamed Brain with Protective Effects of Type 1 cDCs

open access: yesCell Reports, 2020
Summary: Brain CD11c+ cells share features with microglia and dendritic cells (DCs). Sterile inflammation increases brain CD11c+ cells, but their phenotype, origin, and functions remain largely unknown.
Mattia Gallizioli   +16 more
doaj   +1 more source

The correlation between patent foramen ovale and brain ischemia in plateau residents

open access: yesBMC Cardiovascular Disorders, 2021
Background It has been suggested that patent foramen ovale (PFO) contributes to the majority of cryptogenic stroke cases in young people, however, the direct link is still undetermined.
Gang Liu   +5 more
doaj   +1 more source

Neonatal hypoxia-ischemia in rat elicits a region-specific neurotrophic response in SVZ microglia

open access: yesJournal of Neuroinflammation, 2020
Background Recent findings describe microglia as modulators of neurogenesis in the subventricular zone (SVZ). SVZ microglia in the adult rat are thought to adopt a neurotrophic phenotype after ischemic stroke.
Urs Fisch   +4 more
doaj   +1 more source

The neuroprotective effects of intramuscular insulin-like growth factor-I treatment in brain ischemic rats. [PDF]

open access: yesPLoS ONE, 2013
Brain ischemia leads to muscle inactivity-induced atrophy and may exacerbate motor function deficits. Intramuscular insulin-like growth factor I (IGF-I) injection has been shown to alleviate the brain ischemia-induced muscle atrophy and thus improve the ...
Heng-Chih Chang   +4 more
doaj   +1 more source

Brain Ischemia as a Prelude to Alzheimer's Disease

open access: yesFrontiers in Aging Neuroscience, 2021
Transient ischemic brain injury causes massive neuronal death in the hippocampus of both humans and animals. This was accompanied by progressive atrophy of the hippocampus, brain cortex, and white matter lesions.
Ryszard Pluta   +2 more
doaj   +1 more source

CNS-border associated macrophages respond to acute ischemic stroke attracting granulocytes and promoting vascular leakage

open access: yesActa Neuropathologica Communications, 2018
The central nervous system (CNS) contains several types of immune cells located in specific anatomic compartments. Macrophages reside at the CNS borders surrounding the brain vessels, in leptomeningeal spaces and the choroid plexus, where they interact ...
Jordi Pedragosa   +13 more
doaj   +1 more source

Protective Effect of Adenosine A2B Receptor Agonist, BAY60-6583, Against Transient Focal Brain Ischemia in Rat

open access: yesFrontiers in Pharmacology, 2021
Cerebral ischemia is a multifactorial pathology characterized first by an acute injury, due to excitotoxicity, followed by a secondary brain injury that develops hours to days after ischemia.
Ilaria Dettori   +8 more
doaj   +1 more source

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