Results 21 to 30 of about 236,627 (316)

Function of BID - a molecule of the bcl-2 family - in ischemic cell death in the brain [PDF]

open access: yes, 2002
Mitochondrial mechanisms, particularly the release of cytochrome c, play a role in the death of nerve and glial cells in cerebral ischemia. We have currently investigated whether BID, a proapoptotic molecule of the bcl-2 family and promoter of the ...
Amin-Hanjani, Sepideh   +5 more
core   +1 more source

Protective Effect of Adenosine A2B Receptor Agonist, BAY60-6583, Against Transient Focal Brain Ischemia in Rat

open access: yesFrontiers in Pharmacology, 2021
Cerebral ischemia is a multifactorial pathology characterized first by an acute injury, due to excitotoxicity, followed by a secondary brain injury that develops hours to days after ischemia.
Ilaria Dettori   +8 more
doaj   +1 more source

The spectrum of Ischemia-induced white matter injury varies with age [PDF]

open access: yes, 2013
Stroke is a neurological condition that targets the whole range of the human population, from the pre-term infant to the elderly and is a major cause of death worldwide (Ingall 2004).
Zammit, Christian   +2 more
core   +1 more source

Parkinsonian Neurotoxins Impair the Pro-inflammatory Response of Glial Cells

open access: yesFrontiers in Molecular Neuroscience, 2019
In the case of Parkinson’s disease (PD), epidemiological studies have reported that pesticide exposure is a risk factor for its pathology. It has been suggested that some chemical agents, such as rotenone and paraquat, that inhibit the mitochondrial ...
Neus Rabaneda-Lombarte   +5 more
doaj   +1 more source

Metabolism of biogenic amines in acute cerebral ischemia: Influence of systemic hyperglycemia [PDF]

open access: yesActa Veterinaria, 2012
Dopamine, norepinephrine and serotonin are biogenic amines which are transmitters of the central nervous system. The effects of ischemia on the brain parenchyma depends on many factors, such is the mechanism of blood flow interruption, velocity of the
Milovanović Aleksandar   +7 more
doaj   +1 more source

Transplantation of human neural stem/progenitor cells overexpressing galectin-1 improves functional recovery from focal brain ischemia in the mongolian gerbil

open access: yesMolecular Brain, 2011
Transplantation of human neural stem/progenitor cells (hNSPCs) is a promising method to regenerate tissue from damage and recover function in various neurological diseases including brain ischemia.
Yamane Junichi   +10 more
doaj   +1 more source

Review on herbal medicine on brain ischemia and reperfusion

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2015
Brain ischemia and reperfusion is the leading cause of serious and long-range disability in the world. Clinically significant changes in central nervous system function are observed following brain ischemia and reperfusion.
Nahid Jivad, Zahra Rabiei
doaj   +1 more source

Effects and Mechanisms of Exosomes from Different Sources in Cerebral Ischemia

open access: yesCells, 2022
Cerebral ischemia refers to the symptom of insufficient blood supply to the brain. Cells of many different origins participate in the process of repairing damage after cerebral ischemia occurs, in which exosomes secreted by the cells play important roles.
Ruoxi Xie   +4 more
doaj   +1 more source

Inflammatory Responses in Brain Ischemia [PDF]

open access: yesCurrent Medicinal Chemistry, 2015
Brain infarction causes tissue death by ischemia due to occlusion of the cerebral vessels and recent work has shown that post stroke inflammation contributes significantly to the development of ischemic pathology. Because secondary damage by brain inflammation may have a longer therapeutic time window compared to the rescue of primary damage following ...
Kawabori, Masahito, Yenari, Midori A
openaire   +4 more sources

Ischemic postconditioning protects against ischemic brain injury by up-regulation of acid-sensing ion channel 2a

open access: yesNeural Regeneration Research, 2016
Ischemic postconditioning renders brain tissue tolerant to brain ischemia, thereby alleviating ischemic brain injury. However, the exact mechanism of action is still unclear.
Wang-sheng Duanmu   +5 more
doaj   +1 more source

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