Results 21 to 30 of about 2,097,140 (305)

CNS-border associated macrophages respond to acute ischemic stroke attracting granulocytes and promoting vascular leakage

open access: yesActa Neuropathologica Communications, 2018
The central nervous system (CNS) contains several types of immune cells located in specific anatomic compartments. Macrophages reside at the CNS borders surrounding the brain vessels, in leptomeningeal spaces and the choroid plexus, where they interact ...
Jordi Pedragosa   +13 more
doaj   +1 more source

Brain Ischemia as a Prelude to Alzheimer's Disease

open access: yesFrontiers in Aging Neuroscience, 2021
Transient ischemic brain injury causes massive neuronal death in the hippocampus of both humans and animals. This was accompanied by progressive atrophy of the hippocampus, brain cortex, and white matter lesions.
Ryszard Pluta   +2 more
doaj   +1 more source

Function of BID - a molecule of the bcl-2 family - in ischemic cell death in the brain [PDF]

open access: yes, 2002
Mitochondrial mechanisms, particularly the release of cytochrome c, play a role in the death of nerve and glial cells in cerebral ischemia. We have currently investigated whether BID, a proapoptotic molecule of the bcl-2 family and promoter of the ...
Amin-Hanjani, Sepideh   +5 more
core   +1 more source

FUNCTIONAL ISCHEMIA OF THE BRAIN [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1881
n ...
openaire   +1 more source

Metabolism of biogenic amines in acute cerebral ischemia: Influence of systemic hyperglycemia [PDF]

open access: yesActa Veterinaria, 2012
Dopamine, norepinephrine and serotonin are biogenic amines which are transmitters of the central nervous system. The effects of ischemia on the brain parenchyma depends on many factors, such is the mechanism of blood flow interruption, velocity of the
Milovanović Aleksandar   +7 more
doaj   +1 more source

Parkinsonian Neurotoxins Impair the Pro-inflammatory Response of Glial Cells

open access: yesFrontiers in Molecular Neuroscience, 2019
In the case of Parkinson’s disease (PD), epidemiological studies have reported that pesticide exposure is a risk factor for its pathology. It has been suggested that some chemical agents, such as rotenone and paraquat, that inhibit the mitochondrial ...
Neus Rabaneda-Lombarte   +5 more
doaj   +1 more source

Protective Effect of Adenosine A2B Receptor Agonist, BAY60-6583, Against Transient Focal Brain Ischemia in Rat

open access: yesFrontiers in Pharmacology, 2021
Cerebral ischemia is a multifactorial pathology characterized first by an acute injury, due to excitotoxicity, followed by a secondary brain injury that develops hours to days after ischemia.
Ilaria Dettori   +8 more
doaj   +1 more source

The spectrum of Ischemia-induced white matter injury varies with age [PDF]

open access: yes, 2013
Stroke is a neurological condition that targets the whole range of the human population, from the pre-term infant to the elderly and is a major cause of death worldwide (Ingall 2004).
Zammit, Christian   +2 more
core   +1 more source

Transplantation of human neural stem/progenitor cells overexpressing galectin-1 improves functional recovery from focal brain ischemia in the mongolian gerbil

open access: yesMolecular Brain, 2011
Transplantation of human neural stem/progenitor cells (hNSPCs) is a promising method to regenerate tissue from damage and recover function in various neurological diseases including brain ischemia.
Yamane Junichi   +10 more
doaj   +1 more source

Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration [PDF]

open access: yes, 2010
Ischemic stroke is the second leading cause of death worldwide. Only one moderately effective therapy exists, albeit with contraindications that exclude 90% of the patients.
Shah, Ajay M.   +142 more
core   +1 more source

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