Results 31 to 40 of about 329,254 (353)

Wide therapeutic time window for nimesulide neuroprotection in a model of transient focal cerebral ischemia in the rat [PDF]

open access: yes, 2004
Results from several studies indicate that cyclooxygenase-2 (COX-2) is involved ischemic brain injury. The purpose of this study was to evaluate the neuroprotective effects of the selective COX-2 inhibitor nimesulide on cerebral infarction and ...
Candelario-Jalil, Eduardo   +4 more
core   +1 more source

Parkinsonian Neurotoxins Impair the Pro-inflammatory Response of Glial Cells

open access: yesFrontiers in Molecular Neuroscience, 2019
In the case of Parkinson’s disease (PD), epidemiological studies have reported that pesticide exposure is a risk factor for its pathology. It has been suggested that some chemical agents, such as rotenone and paraquat, that inhibit the mitochondrial ...
Neus Rabaneda-Lombarte   +5 more
doaj   +1 more source

Effects and Mechanisms of Exosomes from Different Sources in Cerebral Ischemia

open access: yesCells, 2022
Cerebral ischemia refers to the symptom of insufficient blood supply to the brain. Cells of many different origins participate in the process of repairing damage after cerebral ischemia occurs, in which exosomes secreted by the cells play important roles.
Ruoxi Xie   +4 more
doaj   +1 more source

Ischemia–reperfusion impairs blood–brain barrier function and alters tight junction protein expression in the ovine fetus [PDF]

open access: yes, 2012
The blood–brain barrier is a restrictive interface between the brain parenchyma and the intravascular compartment. Tight junctions contribute to the integrity of the blood–brain barrier.
Banks, W. A.   +9 more
core   +2 more sources

Barrier mechanisms in neonatal stroke. [PDF]

open access: yes, 2014
Clinical data continue to reveal that the incidence of perinatal stroke is high, similar to that in the elderly. Perinatal stroke leads to significant morbidity and severe long-term neurological and cognitive deficits, including cerebral palsy ...
Chip, Sophorn   +2 more
core   +2 more sources

Review on herbal medicine on brain ischemia and reperfusion

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2015
Brain ischemia and reperfusion is the leading cause of serious and long-range disability in the world. Clinically significant changes in central nervous system function are observed following brain ischemia and reperfusion.
Nahid Jivad, Zahra Rabiei
doaj   +1 more source

Ischemic postconditioning protects against ischemic brain injury by up-regulation of acid-sensing ion channel 2a

open access: yesNeural Regeneration Research, 2016
Ischemic postconditioning renders brain tissue tolerant to brain ischemia, thereby alleviating ischemic brain injury. However, the exact mechanism of action is still unclear.
Wang-sheng Duanmu   +5 more
doaj   +1 more source

Traumatic brain ischemia during neuro intensive care: myth rather than fact [PDF]

open access: yesArquivos de Neuro-Psiquiatria, 2001
In non-missile severe acute brain trauma, brain ischemia was a frequent finding in cadavers. Studies during neuro intensive care, however, have failed to disclose brain ischemia under most circumstances, except when cerebral hemodynamic and metabolic ...
Julio Cruz
doaj   +1 more source

Function of BID - a molecule of the bcl-2 family - in ischemic cell death in the brain [PDF]

open access: yes, 2002
Mitochondrial mechanisms, particularly the release of cytochrome c, play a role in the death of nerve and glial cells in cerebral ischemia. We have currently investigated whether BID, a proapoptotic molecule of the bcl-2 family and promoter of the ...
Amin-Hanjani, Sepideh   +5 more
core   +1 more source

FUNCTIONAL ISCHEMIA OF THE BRAIN [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1881
n ...
openaire   +1 more source

Home - About - Disclaimer - Privacy