Results 31 to 40 of about 339,139 (331)
Emergency decompressive craniectomy after removal of convexity meningiomas [PDF]
, 2016 BACKGROUND: Convexity meningiomas are benign brain tumors that are amenable to complete surgical resection and are associated with a low complication rate.
D'Elia, Alessandro +8 more
core +2 more sources
Journal of Neuroinflammation, 2023 Background and purpose Cerebral ischemia‒reperfusion injury causes significant harm to human health and is a major contributor to stroke-related deaths worldwide. Current treatments are limited, and new, more effective prevention and treatment strategies
Zhaohui Ruan +7 more
doaj +1 more source
Post-ischaemic treatment with the cyclooxygenase-2 inhibitor nimesulide reduces blood-brain barrier disruption and leukocyte infiltration following transient focal cerebral ischaemia in rats [PDF]
, 2007 Several studies suggest that cyclooxygenase (COX)-2 plays a pivotal role in the progression of ischemic brain damage. In the present study, we investigated the effects of selective inhibition of COX-2 with nimesulide (12 mg/kg) and selective inhibition ...
Candelario-Jalil, Eduardo +4 more
core +2 more sources
Phase I and Phase II Therapies for Acute Ischemic Stroke: An Update on Currently Studied Drugs in Clinical Research. [PDF]
, 2017 Acute ischemic stroke is a devastating cause of death and disability, consequences of which depend on the time from ischemia onset to treatment, the affected brain region, and its size.
Akyol, Onat +6 more
core +3 more sources
Neural Regeneration Research, 2017 Myocardial ischemia/reperfusion injury can lead to severe brain injury. Glycogen synthase kinase 3 beta is known to be involved in myo-cardial ischemia/reperfusion injury and diabetes mellitus. However, the precise role of glycogen synthase kinase 3 beta
Bo Zhao +7 more
doaj +1 more source
Molecules, 2021 Transient ischemia in brains causes neuronal damage, gliosis, and blood–brain barrier (BBB) breakdown, which is related to ischemia-induced brain dysfunction.
Tae-Kyeong Lee +10 more
doaj +1 more source
Hypoxia–ischemia in the immature brain [PDF]
Journal of Experimental Biology, 2004 SUMMARYThe immature brain has long been considered to be resistant to the damaging effects of hypoxia and hypoxia–ischemia (H/I). However, it is now appreciated that there are specific periods of increased vulnerability, which relate to the developmental stage at the time of the insult.
Susan J. Vannucci, Henrik Hagberg
openaire +3 more sources
Hyperglycemia and Focal Brain Ischemia [PDF]
Journal of Cerebral Blood Flow & Metabolism, 1999 The influence of hyperglycemic ischemia on tissue damage and cerebral blood flow was studied in rats subjected to short-lasting transient middle cerebral artery (MCA) occlusion. Rats were made hyperglycemic by intravenous infusion of glucose to a blood glucose level of about 20 mmol/L, and MCA occlusion was performed with the intraluminar filament ...
Bo K. Siesjö +2 more
openaire +2 more sources
Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration [PDF]
, 2010 Ischemic stroke is the second leading cause of death worldwide. Only one moderately effective therapy exists, albeit with contraindications that exclude 90% of the patients.
A Berna-Erro +84 more
core +6 more sources
Hypothermia selectively protects the anterior forebrain mesocircuit during global cerebral ischemia
Neural Regeneration Research, 2022 Hypothermia is an important protective strategy against global cerebral ischemia following cardiac arrest. However, the mechanisms of hypothermia underlying the changes in different regions and connections of the brain have not been fully elucidated ...
Xiao-Hua Wang +7 more
doaj +1 more source