Function of BID - a molecule of the bcl-2 family - in ischemic cell death in the brain [PDF]
, 2002 Mitochondrial mechanisms, particularly the release of cytochrome c, play a role in the death of nerve and glial cells in cerebral ischemia. We have currently investigated whether BID, a proapoptotic molecule of the bcl-2 family and promoter of the ...
Amin-Hanjani, Sepideh +5 more
core +1 more source
Tau Protein Dysfunction after Brain Ischemia
Journal of Alzheimer's Disease, 2018 Brain ischemia comprises blood-brain barrier, glial, and neuronal cells. The blood–brain barrier controls permeability of different substances and the composition of the neuronal cells ‘milieu’, which is required for their physiological functioning ...
R. Pluta +3 more
semanticscholar +1 more source
Neural Regeneration Research, 2016 Ischemic postconditioning renders brain tissue tolerant to brain ischemia, thereby alleviating ischemic brain injury. However, the exact mechanism of action is still unclear.
Wang-sheng Duanmu +5 more
doaj +1 more source
Traumatic brain ischemia during neuro intensive care: myth rather than fact [PDF]
Arquivos de Neuro-Psiquiatria, 2001 In non-missile severe acute brain trauma, brain ischemia was a frequent finding in cadavers. Studies during neuro intensive care, however, have failed to disclose brain ischemia under most circumstances, except when cerebral hemodynamic and metabolic ...
Julio Cruz
doaj +1 more source
Multimodal pathophysiological dataset of gradual cerebral ischemia in a cohort of juvenile pigs [PDF]
Sci Data 2021, 2020 Ischemic brain injuries are frequent and difficult to detect reliably or early. We present the multi-modal data set containing cardiovascular (blood pressure, blood flow, electrocardiogram) and brain electrical activities to derive electroencephalogram (EEG) biomarkers of corticothalamic communication under normal, sedation and hypoxic/ischemic ...
arxiv +1 more source
Ischemia–reperfusion impairs blood–brain barrier function and alters tight junction protein expression in the ovine fetus [PDF]
, 2012 The blood–brain barrier is a restrictive interface between the brain parenchyma and the intravascular compartment. Tight junctions contribute to the integrity of the blood–brain barrier.
Banks, W. A. +9 more
core +2 more sources
Pre- and post-estrogen administration in global cerebral ischemia reduces blood-brain barrier breakdown in ovariectomized rats [PDF]
, 2015 The aim of present study was to determine the effect of estrogen treatment on blood-brain barrier permeability in rats with induced global cerebral ischemia.
Bahçekapılı, N. +4 more
core +1 more source
International Journal of Molecular Sciences, 2018 In recent years, ongoing interest in ischemic brain injury research has provided data showing that ischemic episodes are involved in the development of Alzheimer’s disease-like neuropathology.
R. Pluta +2 more
semanticscholar +1 more source
Role of mTORC1 Controlling Proteostasis after Brain Ischemia
Frontiers in Neuroscience, 2018 Intense efforts are being undertaken to understand the pathophysiological mechanisms triggered after brain ischemia and to develop effective pharmacological treatments.
M. Pérez‐Álvarez +3 more
semanticscholar +1 more source
Phase I and Phase II Therapies for Acute Ischemic Stroke: An Update on Currently Studied Drugs in Clinical Research. [PDF]
, 2017 Acute ischemic stroke is a devastating cause of death and disability, consequences of which depend on the time from ischemia onset to treatment, the affected brain region, and its size.
Akyol, Onat +6 more
core +3 more sources