Results 91 to 100 of about 13,017 (250)

DISTINGUISHING LYMPHATICS FROM BLOOD VESSELS IN NORMAL AND DISEASED SKIN

open access: yes, 2017
If it were true that lymphatics are essential for the removal of macromolecules and in this way the oncotic and hydrostatic pressures within the interstitium are determined; if it were true that lymphatics are the principal pathway for the exit of ...
Ryan, TJ
core  

New insights into phototherapy of glioblastoma: the meningeal lymphatics and sleep

open access: yes
The meningeal lymphatics (MLVs) play an important role in immunity and maintaining homeostasis of the central nervous system. Sleep is a natural state when lymphatic drainage becomes maximally active and, along with the flow of fluids, toxins and ...
Viktoria Adushkina   +6 more
core   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

open access: yesBMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou   +6 more
wiley   +1 more source

Paraplegia is not a diagnosis: Spinal tuberculosis deserves a place on the clinical radar screen: Awakening call to clinicians

open access: yesInternational Journal of Mycobacteriology, 2012
Disseminated Tuberculosis(TB) occurs through lymphohaematogenous dissemination of M. tuberculosis. Although it is more common in young children and those who are having risk factors like having acquired or innate immunodeficiency, weak immune system ...
Liaqat Ali Chaudhry   +2 more
doaj   +1 more source

Marine silicon for biomedical sustainability

open access: yesBMEMat, EarlyView.
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han   +3 more
wiley   +1 more source

Overcoming intranasal delivery barriers with ultrastable polyzwitterionic siRNA nanocages for enhanced glioblastoma therapy

open access: yesBMEMat, EarlyView.
A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie   +12 more
wiley   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

open access: yesBMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma   +8 more
wiley   +1 more source

Microenvironmental Regulation of Tumor Progression and Therapeutic Response in Brain Metastasis

open access: yesFrontiers in Immunology, 2019
Cellular and non-cellular components of the tumor microenvironment (TME) are emerging as key regulators of primary tumor progression, organ-specific metastasis, and therapeutic response.
Michael Schulz   +7 more
doaj   +1 more source

Arterial Perivascular Space‐Mediated Solute Transport in the Mouse Brain

open access: yesExploration, EarlyView.
The mechanisms underlying solute clearance from the brain parenchyma remain debated, with competing hypotheses involving bulk cerebrospinal fluid flow versus perivascular transport. Using multimodal in vivo imaging and computational modeling in mice, this study demonstrates that arterial pulsation drives bidirectional solute movement within the ...
Shiyong Li   +9 more
wiley   +1 more source

MR Imaging of Neurofluids in the Developing Brain.

open access: yes
Contains fulltext : 318736.pdf (Publisher’s version ) (Open Access)The different fluid compartments in the developing brain work together to facilitate the delivery of nutrients, neurotransmitters, and neuromodulators. The cerebrospinal
Klein, W.M.   +2 more
core   +1 more source

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