Results 81 to 90 of about 1,655,573 (298)

Hepatic lymphatics: anatomy and related diseases [PDF]

open access: yes, 2021
The liver normally produces a large amount of lymph. It is estimated that between 25% and 50% of the lymph received by the thoracic duct comes from the liver. In normal conditions, hepatic lymphatics are not depicted on cross-sectional imaging.
Terraz, Sylvain   +5 more
core  

Lymphatic network drainage resolves cerebral edema and facilitates recovery from experimental cerebral malaria

open access: yesCell Reports
Summary: While brain swelling, associated with fluid accumulation, is a known feature of pediatric cerebral malaria (CM), how fluid and macromolecules are drained from the brain during recovery from CM is unknown.
Michael J. Haley   +8 more
doaj   +1 more source

Immune Checkpoint Inhibitor as a Fifth Component of Lipid Nanoparticles Enables Lymph Node‐Targeting and Augments mRNA Vaccine Efficacy

open access: yesAdvanced Science, EarlyView.
Here, a PDL1 inhibitor is employed as a fifth component to modify lipid nanoparticles (LNPs). PDL1 inhibitor‐loaded LNPs show enhanced lymph node targeting, resulting in greater lymph node expansion, immune cell infiltration, and improved mRNA vaccine efficacy. This fifth component LNP could be a novel platform for mRNA vaccines.
Minki Ha   +5 more
wiley   +1 more source

Fluid Pump Mechanisms in Initial Lymphatics

open access: yes, 1994
Initial lymphatics are noncontractile and drain into collecting lymphatics with a smooth muscle intima, valves, and peristalsis, How does interstitial fluid enter the initial lymphatics?
GW Schmid-Schonbein, BW Zweifach
core   +1 more source

Lymphatic system in the brain

open access: yesAnnals of Medicine & Surgery, 2022
Khan, Safinaz   +2 more
openaire   +2 more sources

Versatile Microgel Platform for Intervertebral Disc Degeneration Therapy: Targeting Pericyte‐Mediated Fibrosis and Protecting Nucleus Pulposus Cells

open access: yesAdvanced Science, EarlyView.
The engineered MMS@TRP microgel enables targeted, acid‐responsive delivery of a miR‐21 inhibitor to pericytes. It effectively suppresses disc fibrosis by inhibiting TGF‐β signaling while protecting nucleus pulposus cells via sustained, antioxidant tannic acid release.
Fei Ma   +12 more
wiley   +1 more source

A National Consensus Survey for Current Practice in Brain Tumor Management I: Antiepileptic Drug and Steroid Usage [PDF]

open access: yes, 2020
Background: The Guideline Working Group of the Korean Society for Neuro-Oncology (KSNO) conducted a nationwide questionnaire survey for diverse queries faced in the treatment of brain tumors. As part I of the survey, the aim of this study is to evaluate
김세훈, 윤홍인, 장종희
core   +1 more source

Optimizing Cancer Vaccinations Using a Physiologically‐Based Pharmacokinetic/Pharmacodynamic (PBPK/PD) Model

open access: yesAdvanced Science, EarlyView.
Where and when should a cancer vaccine be administered? A whole‐body PBPK model demonstrates that systemic immune transport critically determines vaccination efficacy. By simulating how organ‐specific immune interactions influence treatment response, the study provides a quantitative framework for optimizing cancer vaccination strategies.
Mohammad R. Nikmaneshi   +2 more
wiley   +1 more source

The regulation of brain states by neuroactive substances distributed via the cerebrospinal fluid; a review

open access: yesCerebrospinal Fluid Research, 2010
The cerebrospinal fluid (CSF) system provides nutrients to and removes waste products from the brain. Recent findings suggest, however, that in addition, the CSF contains message molecules in the form of actively released neuroactive substances.
Veening Jan G, Barendregt Henk P
doaj   +1 more source

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