Results 81 to 90 of about 12,817 (250)
Arterial Perivascular Space‐Mediated Solute Transport in the Mouse Brain
Exploration, EarlyView.The mechanisms underlying solute clearance from the brain parenchyma remain debated, with competing hypotheses involving bulk cerebrospinal fluid flow versus perivascular transport. Using multimodal in vivo imaging and computational modeling in mice, this study demonstrates that arterial pulsation drives bidirectional solute movement within the ...
Shiyong Li +9 more
wiley +1 more source
Head &Neck, EarlyView.ABSTRACT Background Following promising initial results of the robotic‐assisted extended “Sistrunk” approach (RESA) that uses a submental incision to hypopharyngeal and laryngeal tumors, bypassing the base of tongue, we report its further development: submental approach robotic‐assisted neck dissection (SARAND), intended to enable bilateral neck ...
Bartosz P. Wojtera +5 more
wiley +1 more source
International Journal of Mycobacteriology, 2012 Disseminated Tuberculosis(TB) occurs through lymphohaematogenous dissemination of M. tuberculosis. Although it is more common in young children and those who are having risk factors like having acquired or innate immunodeficiency, weak immune system ...
Liaqat Ali Chaudhry +2 more
doaj +1 more source
Head &Neck, EarlyView.ABSTRACT Background Robust outcome data for anterior skull base cutaneous squamous cell carcinoma (cSCC) are limited, particularly as emerging therapies reshape management. We evaluated survival and prognostic factors following craniofacial resection. Methods Retrospective multi‐institutional case‐series (1995–2015) of patients who underwent skull base
Michael J. C. Schachtel +52 more
wiley +1 more source
New Brain Lymphatic Vessels Drain Old Concepts
EBioMedicine, 2015 The brain has traditionally been considered an immune privileged organ, in part due to the lack of evidence for lymphatic vasculature (Galea et al., 2007). Two centuries ago, the existence of lymphatic vessels on the surface of the human brain was proposed but it has since been widely dismissed (Lukic et al., 2003).
Dissing-Olesen, Lasse +2 more
openaire +5 more sources
International Journal of Cancer, EarlyView.ABSTRACT Clinical trials combining radiotherapy (RT) with immune checkpoint blockade (ICB) have shown improved outcomes in only a fraction of patients, and optimal strategies for integrating these modalities remain under intense investigation. With a few exceptions, phase III combination trials have yielded disappointing results.
Xuanwei Zhang +10 more
wiley +1 more source
Microenvironmental Regulation of Tumor Progression and Therapeutic Response in Brain Metastasis
Frontiers in Immunology, 2019 Cellular and non-cellular components of the tumor microenvironment (TME) are emerging as key regulators of primary tumor progression, organ-specific metastasis, and therapeutic response.
Michael Schulz +7 more
doaj +1 more source
Meningeal lymphatics “drain” brain tumors [PDF]
Cell Research, 2020 Mitsuhiro, Kanamori, Jonathan, Kipnis
openaire +2 more sources
iMetaOmics, EarlyView.The gut–mammary axis integrates intestinal health with mammary function through neural, endocrine, and immune pathways. Nutritional interventions (probiotics, prebiotics, metabolites) improve gut microecology, generating microbial signals that travel via the axis to the mammary gland. There, they relieve inflammation, enhance milk quality and lactation,
Aolong Zhou +29 more
wiley +1 more source
iMeta, EarlyView.Microbiome age (MA) has emerged as an innovative biomarker of biological aging, reflecting host aging trajectories through dynamic alterations in microbial composition, function, and host–microbe interactions across multiple body ecosystems. Diverse computational strategies—including traditional machine learning, deep learning, and multi‐omics ...
Zhexin Ni +26 more
wiley +1 more source