Results 161 to 170 of about 18,873 (192)
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Assembling human brain organoids

Science, 2019
Three-dimensional assembloids can be used to study human development and ...
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Brain Organoid Computing for Artificial Intelligence

2023
Abstract Brain-inspired hardware emulates the structure and working principles of a biological brain and may address the hardware bottleneck for fast-growing artificial intelligence (AI). Current brain-inspired silicon chips are promising but still limit their power to fully mimic brain function for AI computing. Here,
Hongwei, Cai   +8 more
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Interdisciplinary approaches to brain organoid biology

Folia Pharmacologica Japonica, 2023
Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) have been widely used as materials for regenerative medicine and for modeling development and disease because of their pluripotency to differentiate into all cell types of the body.
Tomoki, Kodera, Fumitaka, Osakada
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Brain organoid-on-a-chip to create multiple domains in forebrain organoids

2023
Abstract Brain organoids are three-dimensionally reconstructed brain tissue derived from pluripotent stem cells in vitro. 3D tissue cultures have opened new avenues for exploring development and disease modeling. However, some physiological conditions, including signaling gradients in 3D cultures, have not yet been easily achieved. Here,
Yuan-Chen Tsai   +11 more
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Brain organoids get vascularized

Nature Biotechnology, 2018
Transplantation of cerebral organoids into the mouse brain overcomes some limitations of in vitro systems.
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Application of brain organoids in neurodevelopmental disorders

Biochemical and Biophysical Research Communications
Understanding the etiology of human neurological and psychiatric disorders remains challenging due to species-specific genomic architectures, prolonged developmental timelines, and the unique cytoarchitectural features of the human brain, which are inadequately replicated in conventional animal models.
Chao, Zhao   +4 more
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Brain organoids

2023
Madison R. Glass   +4 more
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Brain Organoids in the Study of Psychiatric Disorders

JAMA Psychiatry
This article discusses the use of brain organoids in modeling the biological mechanisms of psychiatric disease.
Yukyeong, Lee   +2 more
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