Results 221 to 230 of about 26,410 (296)

Axially multifocal metalens for 3D volumetric photoacoustic imaging of neuromelanin in live brain organoid. [PDF]

Sci Adv
Barulin A, Barulina E, Oh DK, Jo Y, Park H, Park S, Kye H, Kim J, Yoo J, Kim J, Bak G, Kim Y, Kang H, Park Y, Park JC, Rho J, Park B, Kim I.   +17 more
europepmc   +1 more source

Liminal Bioethics for Liminal Statuses: A New Method for Analysing Novel Biological Entities

Bioethics, EarlyView.
ABSTRACT Novel biological entities such as cell lines and organoids do not typically fit into established conceptual categories, such as ‘human’ or ‘nonhuman’, ‘gift’ or ‘property’. This makes developing robust ethical principles or policy solutions difficult.
Michael Wee, Ilina Singh
wiley   +1 more source

Protocol for the generation of cultured cortical brain organoid slices. [PDF]

STAR Protoc
Petersilie L, Kafitz KW, Neu LA, Heiduschka S, Le S, Prigione A, Rose CR.   +6 more
europepmc   +1 more source

Morphodynamics of human early brain organoid development

, 2023
Jain A, Gut G, Sanchis-Calleja F, Okamoto R, Streib S, He Z, Zenk F, Santel M, Seimiya M, Holtackers R, Jansen SMJ, Camp JG, Treutlein B.   +12 more
europepmc   +1 more source

Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation?

British Journal of Pharmacology, EarlyView.
Psychedelic drugs that activate 5‐HT2A receptors have been long used for cultural, medicinal and recreational purposes. Interest in psychedelics for treating psychiatric disorders has resurged recently and is well documented; less well recognised are their anti‐inflammatory properties. Growing evidence now demonstrates that psychedelics modulate immune
Omar Qureshi, Jamie Cowley, Ashley Pegg, Alison J. Cooper, John Gordon, Catherine A. Brady, Antonio Belli, Sam Butterworth, Rachel Upthegrove, Nick Andrews, Nicholas M. Barnes   +10 more
wiley   +1 more source

Antiretroviral drug therapy does not reduce neuroinflammation in an HIV-1 infection brain organoid model. [PDF]

J Neuroinflammation
Martinez-Meza S, Premeaux TA, Cirigliano SM, Friday CM, Michael S, Mediouni S, Valente ST, Ndhlovu LC, Fine HA, Furler O'Brien RL, Nixon DF.   +10 more
europepmc   +1 more source

Targeting the noradrenergic‐metabolic axis: A new strategy for sugar‐induced depression subtypes

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Lifestyle is closely related to major depressive disorder (MDD). Given the growing focus on the impact of diet on mental health, this study examined how dietary habits affect the pathophysiology of MDD. Experimental Approach Health check‐up data were analysed. Mice received sucrose under chronic unpredictable mild stress
Takatoshi Sakata, Kazuo Kunisawa, Masaya Hasegawa, Yumiko Seto, Aoi Ogawa, Hitomi Kurahashi, Yasuko Yamamoto, Masao Takemura, Hidetoshi Matunami, Tomoya Sugai, Noriki Kutsumura, Kuniaki Saito, Toshitaka Nabeshima, Akihiro Mouri   +13 more
wiley   +1 more source

Expanding the neuroimmune research toolkit with in vivo brain organoid technologies.

Dis Model Mech
Tian A, Bhattacharya A, Muffat J, Li Y.
europepmc   +1 more source

Covalent fluorescent probes for 2‐arachidonoylglycerol metabolic pathways

British Journal of Pharmacology, EarlyView.
Abstract Covalent fluorescent probes have emerged as versatile chemical tools to visualise active enzymes in complex biological systems. When tailored for specific applications, ranging from activity‐based protein profiling for drug development to high spatiotemporal resolution imaging of enzymatic activities, these probes provide unique insights into ...
Nick D. F. Puijmbroeck, Mario van der Stelt   +1 more
wiley   +1 more source

Advancing insights into virus-induced neurodevelopmental disorders through human brain organoid modelling. [PDF]

Expert Rev Mol Med
Crawford G, Soper O, Kang E, Berg DA.
europepmc   +1 more source