Results 211 to 220 of about 19,404 (259)

Brain organoid maturation and implantation integration based on electrical signals input. [PDF]

J Adv Res
Li XH, Hu N, Chang ZH, Shi JX, Fan X, Chen MM, Bao SQ, Chen C, Zuo JC, Zhang XW, Wang JJ, Ming D.   +11 more
europepmc   +1 more source

Artificial intelligence empowers targeted protein degradation: Core technological innovations, multi‐scenario applications, and translational prospects

Smart Molecules, EarlyView.
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin, Rui Peng, Guangshuai Zhang, Si Yan, Jin Xiao, Zishu Liu, Ziyu Tan, Qingqing Xie, Shangjie Li, Wei Luo, Xiaohe Xiao   +10 more
wiley   +1 more source

Proof of concept for brain organoid-on-a-chip to create multiple domains in forebrain organoids. [PDF]

RSC Adv
Tsai YC, Ozaki H, Morikawa A, Shiraiwa K, Pin AP, Salem AG, Phommahasay KA, Sugita BK, Vu CH, Hammad SM, Kamei KI, Watanabe M.   +11 more
europepmc   +1 more source

Advances in research on layered double hydroxides for biomedical applications

Smart Molecules, EarlyView.
Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang, Zhiping Zhang, Zhao Wang, Hao Zhang, Yen Leng Pak, Yingying Jing, Yurong Guo, Fang Li, Xiao Wang, Quanxiang Han, Lei Yu, Xuejiao Li, Xing Gao, Jibin Song   +13 more
wiley   +1 more source

Editorial: Human brain organoids to model neurodegenerative diseases at the BOSS23 Brain Organoid Summer School. [PDF]

Front Cell Neurosci
Cavaliere F, Hermann DM, Magliaro C.
europepmc   +1 more source

From Transplantology to Organ Medicine: When the Organ Becomes an Independent Platform

Organ Medicine, EarlyView.
Qiang Zhang, Zhiyong Guo, Xiaomin Shi, Guodong Chen, Xiaoshun He   +4 more
wiley   +1 more source

Dolutegravir induces FOLR1 expression during brain organoid development. [PDF]

Front Mol Neurosci
Caiaffa CD, Tukeman G, Delgado CZ, Ambekar YS, Mekonnen TT, Singh M, Rodriguez V, Ricco E, Kraushaar D, Aglyamov SR, Scarcelli G, Larin KV, Finnell RH, Cabrera RM.   +13 more
europepmc   +1 more source

Neuroligin-3 R451C induces gain-of-function gene expression in astroglia in an astroglia-enriched brain organoid model. [PDF]

Cell Regen
Dang R, Dalmia M, Ma Z, Jin M, Aluru K, Mirabella VR, Papetti AV, Cai L, Jiang P.   +8 more
europepmc   +1 more source

Brain organoid as a model to study the role of mitochondria in neurodevelopmental disorders: achievements and weaknesses. [PDF]

Front Cell Neurosci
Coronel R, García-Moreno E, Siendones E, Barrero MJ, Martínez-Delgado B, Santos-Ocaña C, Liste I, Cascajo-Almenara MV.   +7 more
europepmc   +1 more source

Human brain organoid: trends, evolution, and remaining challenges. [PDF]

Neural Regen Res
Li M, Yuan Y, Hou Z, Hao S, Jin L, Wang B.   +5 more
europepmc   +1 more source