Results 201 to 210 of about 26,891 (293)

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Transparency and ongoing communication with participants in brain organoid research: Consensus of an interdisciplinary working group. [PDF]

Stem Cell Reports
Cohn B, Doerr M, Feliciano P, Fullerton SM, Hendriks S, Holm S, Hyun I, Jongsma K, Meagher KM, Ross ME, Stein JL, Terry SF, MacDuffie KE.   +12 more
europepmc   +1 more source

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

Med Research, EarlyView.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang, Diyuan Zhang, Yuqin Zhou, Ling Qian, Yan Wang, Lei Peng, Min Zhao, Hao Tian, Zhenyu Wu, Aiqi Tang, Minghao Sun, Yi Zhang, Xiaowei Qi   +12 more
wiley   +1 more source

Organoids: The Future of Medicine [PDF]

, 2019
Kuo, Jonathan
core  

Brain organoid model systems of neurodegenerative diseases: recent progress and future prospects. [PDF]

Front Neurosci
Shaikh S, Siddique L, Khalifey HT, Mahereen R, Raziq T, Firdous RM, Siddique A, Shakir IM, Ahmed Z, Akbar A, Alshehri EA, Chinappan R, Alzhrani A, Mir TA, Yaqinuddin A.   +14 more
europepmc   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Future challenges for UK regulation of brain organoid research. [PDF]

Med Law Rev
Jackson E.
europepmc   +1 more source

Research status and trends of Piezo1 and brain: A bibliometric analysis

Neuroprotection, EarlyView.
This graphical abstract illustrates the workflow and key findings of the bibliometric analysis of Piezo1 in brain research. The primary results were visually centered on a brain graphic highlighting the Piezo1 channel, and three converging research hotspots were identified: neurovascular regulation, calcium signaling, and neuroinflammation.
Yu Liu, Shengzhen Luo, Hao Zhang, Jianqing Lin, Hui Xiao, Yuying Ma, Dongxue Ye, Liang Cong, Yongwang Li   +8 more
wiley   +1 more source

Advancing Glioblastoma Research with Innovative Brain Organoid-Based Models. [PDF]

Cells
Correia CD, Calado SM, Matos A, Esteves F, De Sousa-Coelho AL, Campinho MA, Fernandes MT.   +6 more
europepmc   +1 more source

Altered extracellular matrix structure and elevated stiffness in a brain organoid model for disease. [PDF]

Nat Commun
Karlinski Zur M, Bhattacharya B, Solomonov I, Ben Dror S, Savidor A, Levin Y, Prior A, Sapir T, Harris T, Olender T, Schmidt R, Schwarz JM, Sagi I, Buxboim A, Reiner O.   +14 more
europepmc   +1 more source