Results 11 to 20 of about 3,759,591 (312)
Archives of Neurology, 2008 Mutations that cause autosomal recessive primary microcephaly (MCPH), including MCPH1 through MCPH6, have provided insight into the normal programming that directs brain growth and defines ultimate brain size. The common denominator in these mutations is that they all manifest within neural stem and progenitor cells, decreasing their numbers at various
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Neural stem cells: origin, heterogeneity and regulation in the adult mammalian brain
Development, 2019 In the adult rodent brain, neural stem cells (NSCs) persist in the ventricular-subventricular zone (V-SVZ) and the subgranular zone (SGZ), which are specialized niches in which young neurons for the olfactory bulb (OB) and hippocampus, respectively, are ...
K. Obernier, A. Álvarez-Buylla
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Brain-to-Brain Synchrony in the STEM Classroom [PDF]
CBE—Life Sciences Education, 2020 Recent advances in portable electroencephalography (EEG) now allow researchers to collect brain data from groups of students in real-world classrooms. This Essay highlights how this emerging line of research can open new opportunities for collaboration between discipline-based education researchers and cognitive and social neuroscientists.
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Stem cell research & therapeutics, 2019 Preterm newborns are at high risk of developing neurodevelopmental deficits caused by neuroinflammation leading to perinatal brain injury. Human Wharton’s jelly mesenchymal stem cells (hWJ-MSC) derived from the umbilical cord have been suggested to ...
G. Thomi +4 more
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Early Stem Cell Aging in the Mature Brain
bioRxiv, 2019 Stem cell dysfunction drives many age-related disorders. Identifying mechanisms that initially compromise stem cell function represent early targets to enhance stem cell behavior later in life.
A. Ibrayeva +13 more
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Neural stem cell transplantation therapy for brain ischemic stroke: Review and perspectives
World Journal of Stem Cells, 2019 Brain ischemic stroke is one of the most common causes of death and disability, currently has no efficient therapeutic strategy in clinic. Due to irreversible functional neurons loss and neural tissue injury, stem cell transplantation may be the most ...
Guilong Zhang, Zhijun Zhu, Ye-Zhong Wang
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Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
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Human pluripotent stem cell–derived brain pericyte–like cells induce blood-brain barrier properties
Science Advances, 2018 The authors differentiate human stem cells to brain pericyte–like cells and integrate them into a neurovascular unit model. Brain pericytes play important roles in the formation and maintenance of the neurovascular unit (NVU), and their dysfunction has ...
Matthew J. Stebbins +9 more
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Malignant brain stem hyperthermia caused by brain stem hemorrhage. [PDF]
Stroke, 1994 We report two cases of brain stem hemorrhage characterized by severe hyperthermia, rhabdomyolysis, acute renal failure, and a rapidly fatal course. A 55-year-old man and a 65-year-old man were admitted with coma-producing brain stem hemorrhage accompanied by hyperthermia. Both underwent ventricular drainage.
Tomikatsu Toyoda +4 more
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