Results 21 to 30 of about 379,210 (125)

Translationally Relevant Magnetic Resonance Imaging Markers in a Ferret Model of Closed Head Injury

open access: yesFrontiers in Neuroscience, 2022
Pre-clinical models of traumatic brain injury (TBI) have been the primary experimental tool for understanding the potential mechanisms and cellular alterations that follow brain injury, but the human relevance and translational value of these models are ...
Elizabeth B. Hutchinson   +18 more
doaj   +1 more source

Synthetic magnetic resonance images for domain adaptation: Application to fetal brain tissue segmentation [PDF]

open access: yesarXiv, 2021
The quantitative assessment of the developing human brain in utero is crucial to fully understand neurodevelopment. Thus, automated multi-tissue fetal brain segmentation algorithms are being developed, which in turn require annotated data to be trained.
arxiv  

Inter-axonal molecular crosstalk via Lumican proteoglycan sculpts murine cervical corticospinal innervation by distinct subpopulations

open access: yesCell Reports, 2023
Summary: How CNS circuits sculpt their axonal arbors into spatially and functionally organized domains is not well understood. Segmental specificity of corticospinal connectivity is an exemplar for such regional specificity of many axon projections ...
Yasuhiro Itoh   +4 more
doaj  

Efficacy of Intravenous Immunoglobulins against Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids: A Case Report

open access: yesCase Reports in Neurology, 2023
Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory disease of the central nervous system that predominantly affects the brainstem. Apart from corticosteroids, there are few reported
Takumi Tsuchida   +2 more
doaj   +1 more source

Astroglial Control of the Antidepressant-Like Effects of Prefrontal Cortex Deep Brain Stimulation

open access: yesEBioMedicine, 2015
Although deep brain stimulation (DBS) shows promising efficacy as a therapy for intractable depression, the neurobiological bases underlying its therapeutic action remain largely unknown.
A. Etiévant   +17 more
doaj   +1 more source

Case Report: Endoscopic trans-cerebellar medullary fissure approach for the management of brainstem hemorrhage

open access: yesFrontiers in Neurology, 2023
ObjectiveBrainstem hematoma (BSH) is a high-risk condition that can lead to deadly and disabling consequences if not properly managed. However, recent advances in endoscopic techniques, employed for removing supratentorial intracerebral hemorrhage have ...
Xue-Jian Wang   +8 more
doaj   +1 more source

“FlashMap” - A Semi-Automatic Tool for Rapid and Accurate Spatial Analysis of Marker Expression in the Subventricular Zone

open access: yesScientific Reports, 2018
The subventricular zone (SVZ) is a region of ongoing postnatal germinal activity that shows complex spatial heterogeneity. For instance, different SVZ microdomains contain neural stem cells that express distinct transcription factors and generate ...
Stefan Zweifel   +4 more
doaj   +1 more source

Automatic Quantitative Analysis of Brain Organoids via Deep Learning [PDF]

open access: yesarXiv, 2022
Recent advances in brain organoid technology are exciting new ways, which have the potential to change the way how doctors and researchers understand and treat cerebral diseases. Despite the remarkable use of brain organoids derived from human stem cells in new drug testing, disease modeling, and scientific research, it is still heavily time-consuming ...
arxiv  

Crim1 and Kelch-like 14 exert complementary dual-directional developmental control over segmentally specific corticospinal axon projection targeting

open access: yesCell Reports, 2021
Summary: The cerebral cortex executes highly skilled movement, necessitating that it connects accurately with specific brainstem and spinal motor circuitry.
Vibhu Sahni   +3 more
doaj  

Reliability and validity of TMS-EEG biomarkers [PDF]

open access: yesarXiv, 2022
Noninvasive brain stimulation and neuroimaging have revolutionized human neuroscience, with a multitude of applications including diagnostic subtyping, treatment optimization, and relapse prediction. It is therefore particularly relevant to identify robust and clinically valuable brain biomarkers linking symptoms to their underlying neural mechanisms ...
arxiv  

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