Results 31 to 40 of about 835,261 (172)

Corticospinal neuron subpopulation-specific developmental genes prospectively indicate mature segmentally specific axon projection targeting

Cell Reports, 2021
Summary: For precise motor control, distinct subpopulations of corticospinal neurons (CSN) must extend axons to distinct spinal segments, from proximal targets in the brainstem and cervical cord to distal targets in thoracic and lumbar spinal segments ...
Vibhu Sahni, Sara J. Shnider, Denis Jabaudon, Janet H.T. Song, Yasuhiro Itoh, Luciano C. Greig, Jeffrey D. Macklis   +6 more
doaj  

Translationally Relevant Magnetic Resonance Imaging Markers in a Ferret Model of Closed Head Injury

Frontiers in Neuroscience, 2022
Pre-clinical models of traumatic brain injury (TBI) have been the primary experimental tool for understanding the potential mechanisms and cellular alterations that follow brain injury, but the human relevance and translational value of these models are ...
Elizabeth B. Hutchinson, Anakaren Romero-Lozano, Hannah R. Johnson, Andrew K. Knutsen, Andrew K. Knutsen, Asamoah Bosomtwi, Asamoah Bosomtwi, Alexandru Korotcov, Alexandru Korotcov, Anandakumar Shunmugavel, Anandakumar Shunmugavel, Sarah G. King, Susan C. Schwerin, Susan C. Schwerin, Sharon L. Juliano, Sharon L. Juliano, Bernard J. Dardzinski, Bernard J. Dardzinski, Carlo Pierpaoli   +18 more
doaj   +1 more source

Synthetic magnetic resonance images for domain adaptation: Application to fetal brain tissue segmentation [PDF]

arXiv, 2021
The quantitative assessment of the developing human brain in utero is crucial to fully understand neurodevelopment. Thus, automated multi-tissue fetal brain segmentation algorithms are being developed, which in turn require annotated data to be trained.
arxiv  

Inter-axonal molecular crosstalk via Lumican proteoglycan sculpts murine cervical corticospinal innervation by distinct subpopulations

Cell Reports, 2023
Summary: How CNS circuits sculpt their axonal arbors into spatially and functionally organized domains is not well understood. Segmental specificity of corticospinal connectivity is an exemplar for such regional specificity of many axon projections ...
Yasuhiro Itoh, Vibhu Sahni, Sara J. Shnider, Holly McKee, Jeffrey D. Macklis   +4 more
doaj  

Efficacy of Intravenous Immunoglobulins against Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids: A Case Report

Case Reports in Neurology, 2023
Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory disease of the central nervous system that predominantly affects the brainstem. Apart from corticosteroids, there are few reported
Takumi Tsuchida, Shigehisa Ura, Ichiro Yabe   +2 more
doaj   +1 more source

Astroglial Control of the Antidepressant-Like Effects of Prefrontal Cortex Deep Brain Stimulation

EBioMedicine, 2015
Although deep brain stimulation (DBS) shows promising efficacy as a therapy for intractable depression, the neurobiological bases underlying its therapeutic action remain largely unknown.
A. Etiévant, C. Oosterhof, C. Bétry, E. Abrial, M. Novo-Perez, R. Rovera, H. Scarna, C. Devader, J. Mazella, G. Wegener, C. Sánchez, O. Dkhissi-Benyahya, C. Gronfier, V. Coizet, J.M. Beaulieu, P. Blier, G. Lucas, N. Haddjeri   +17 more
doaj   +1 more source

Case Report: Endoscopic trans-cerebellar medullary fissure approach for the management of brainstem hemorrhage

Frontiers in Neurology, 2023
ObjectiveBrainstem hematoma (BSH) is a high-risk condition that can lead to deadly and disabling consequences if not properly managed. However, recent advances in endoscopic techniques, employed for removing supratentorial intracerebral hemorrhage have ...
Xue-Jian Wang, Xue-Jian Wang, Longyao Zhang, Yu-Hua Yin, Yu-Hua Yin, Zhi-Feng Wang, Yi Zhang, Cheng Sun, Zhi-Ming Cui   +8 more
doaj   +1 more source

Disease-specific, neurosphere-derived cells as models for brain disorders [PDF]

, 2010
There is a pressing need for patient-derived cell models of brain diseases that are relevant and robust enough to produce the large quantities of cells required for molecular and functional analyses.
Abrahamsen, G., An, J., Anderson, M., Beckhouse, A.G., Bellette, B., Bennebroek, M., Cecil, R., Chalk, A.M., Cochrane, J., Cook, A.L., Fan, Y., Féron, F., Mackay-Sim, A., Mahler, S., Matigian, N., McCurdy, R., McGrath, J.J., Mellick, G.D., Murrell, W., Nouwens, A., Perry, C., Raju, J., Ravishankar, S., Silburn, P.A., Sue, C.M., Sutharsan, R., Sutherland, G.T., Vitale, A.M., Wells, C.A., Wood, S.A.   +29 more
core   +1 more source

Neural Stem Cells [PDF]

, 2021
Twenty years after the discovery of neural stem cells, the question whether the central nervous system can be considered among regenerative tissues is still open.

core   +1 more source

Uniplanar nystagmus associated with perceptual and cognitive visual dysfunction due to presumed focal ischemic occipital cortical atrophy: a missed diagnosis and new observation [PDF]

, 2012
Uniplanar nystagmus has been described in relation to pathology of the brain stem, retina, optic nerve, sensory visual deprivation, periventricular leucomalacia, and drug toxicity.
Dorris, Liam, Dutton, Gordon N., Philip, Swetha Sara   +2 more
core   +3 more sources