Results 1 to 10 of about 195,791 (228)
Modeling brain and neural crest neoplasms with human pluripotent stem cells [PDF]
Neuro-Oncology, 2023 Abstract Pluripotent stem cells offer unique avenues to study human-specific aspects of disease and are a highly versatile tool in cancer research. Oncogenic processes and developmental programs often share overlapping transcriptomic and epigenetic signatures, which can be reactivated in induced pluripotent stem cells. With the emergence
Cedar Schloo, Lena M. Kutscher
semanticscholar +4 more sources
CONTENT OF STEM TUMOR CD133+ CELLS IN BRAIN NEOPLASMS OF DIFFERENT HISTOLOGICAL TYPE [PDF]
Experimental Oncology, 2017 Today, there are conflicting data on the content of cancer stem cells responsible for recurrence and resistance to chemotherapy in tumors of human brain. The aim of the study was to analyze the content of CD133+ cells in different brain tumors by immunofluorescence assay and immunohistochemical method.
N. I. Lisyaniy +3 more
semanticscholar +6 more sources
La Pediatria medica e chirurgica : Medical and surgical pediatrics, 1993 A sixteen-years-old boy with a brain-stem neoplasia inducing coma was treated with chemotherapeutic agents. It resulted in dramatic clinical and instrumental improvement; radiologic findings were evaluated, showing decreasing dimension of intracranial mass. Brain-stem auditory evoked potentials were highly sensitive.
D Portaleone +9 more
openalex +2 more sources
Mathematical modelling, selection and hierarchical inference to determine the minimal dose in IFN$α$ therapy against Myeloproliferative Neoplasms [PDF]
Mathematical Medicine and Biology: A Journal of the IMA, Volume
41, Issue 2, June 2024, Pages 110-134, 2021 Myeloproliferative Neoplasms (MPN) are blood cancers that appear after acquiring a driver mutation in a hematopoietic stem cell. These hematological malignancies result in the overproduction of mature blood cells and, if not treated, induce a risk of cardiovascular events and thrombosis. Pegylated IFN$\alpha$ is commonly used to treat MPN, but no clear
arxiv +1 more source