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Modeling brain and neural crest neoplasms with human pluripotent stem cells [PDF]

open access: hybridNeuro-Oncology, 2023
Abstract Pluripotent stem cells offer unique avenues to study human-specific aspects of disease and are a highly versatile tool in cancer research. Oncogenic processes and developmental programs often share overlapping transcriptomic and epigenetic signatures, which can be reactivated in induced pluripotent stem cells. With the emergence
Cedar Schloo, Lena M Kutscher
openaire   +3 more sources

CONTENT OF STEM TUMOR CD133+ CELLS IN BRAIN NEOPLASMS OF DIFFERENT HISTOLOGICAL TYPE [PDF]

open access: bronzeExperimental Oncology, 2017
Today, there are conflicting data on the content of cancer stem cells responsible for recurrence and resistance to chemotherapy in tumors of human brain. The aim of the study was to analyze the content of CD133+ cells in different brain tumors by immunofluorescence assay and immunohistochemical method.
Lisyaniy, N.I.   +3 more
openaire   +5 more sources

[The otoneurological assessment of radiotherapy-induced brain stem involvement in patients with rhinopharyngeal neoplasms].

open access: closedActa otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 1992
The authors report a study in which otoneurological tests were employed in order to determine the possibility of radio-induced alterations in the brainstem of patients with a rhinopharyngeal carcinoma, which extended to basicranial structures, who had undergone radiotherapy.
P, Pisani   +4 more
openaire   +2 more sources

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