Results 11 to 20 of about 195,791 (228)

The U2AF65/circNCAPG/RREB1 feedback loop promotes malignant phenotypes of glioma stem cells through activating the TGF-β pathway

Cell Death and Disease, 2023
Glioma is the most aggressive and common malignant neoplasms in human brain tumors. Numerous studies have showed that glioma stem cells (GSCs)drive the malignant progression of gliomas. Recent studies have revealed that circRNAs can maintain stemness and
Hao Li, Yang Jiang, Jinpeng Hu, Jinkun Xu, Lian Chen, Guoqing Zhang, Junshuang Zhao, Shengliang Zong, Zhengting Guo, Xinqiao Li, Xiang Zhao, Zhitao Jing   +11 more
doaj   +2 more sources

Pediatric Non–Brain Stem High-Grade Glioma: A Single-Center Experience

Indian Journal of Neurosurgery, 2020
Background Pediatric high-grade gliomas (PHGGs) consist of a heterogeneous class of central nervous system (CNS) neoplasms with a poor prognosis. We aimed to present our 10-year experience in the management of children with high-grade glioma focusing on ...
Ehsan Alimohammadi, Seyed Reza Bagheri, Nasrin Delfani, Roya Safari-Faramani, Maryam Janatolmakan   +4 more
doaj   +2 more sources

Efficacy of the new therapeutic approach in curing malignant neoplasms on the model of human glioblastoma

Cancer Biology & Medicine, 2021
Objective: Glioma is a highly invasive tumor, frequently disposed in essential areas of the brain, which makes its surgical excision extremely difficult; meanwhile adjuvant therapy remains quite ineffective.
Evgeniya V. Dolgova, Oleg M. Andrushkevich, Polina E. Kisaretova, Anastasia S. Proskurina, Genrikh S. Ritter, Tatyana D. Dubatolova, Margarita V. Romanenko, Oleg S. Taranov, Yaroslav R. Efremov, Evgeniy L. Zavyalov, Alexandr V. Romaschenko, Sergey V. Mishinov, Svetlana S. Kirikovich, Evgeniy V. Levites, Ekaterina A. Potter, Alexandr A. Ostanin, Elena R. Chernykh, Stanislav Yu. Roshchin, Anatoliy V. Bervitskiy, Galina I. Moysak, Jamil A. Rzaev, Sergey S. Bogachev   +21 more
doaj   +2 more sources

Cesarean section in spinal anesthesia on a patient with mesencephalic tumor and ventriculoperitoneal drainage -A case report- [PDF]

Korean Journal of Anesthesiology, 2012
A seventeen-year-old pregnant woman with a mesencephalic tumor and ventriculoperitoneal (VP) drainage was admitted to the hospital at full term pregnancy to give birth.
Ivana Hirs, Patricia Grbcic
doaj   +1 more source

Problems of Effective Therapy of Brain Neoplasms: Fatality or Positive Outlook

Journal of Clinical Review & Case Reports, 2020
The search for “mesenchymal stem cells, glioma, and treatment” showed 446 articles in PubMed on December 18, 2019. The results of scientific research presented in articles by professionals on oncological topics focus on the problem of malignancy of ...

semanticscholar   +1 more source

Autophagic-Related Proteins in Brain Gliomas: Role, Mechanisms, and Targeting Agents

Cancers, 2023
Simple Summary The aim of the present review is to discuss the autophagy, a well-known cellular process, able to remove damaged intracellular organelles as well as macromolecules and misfolded proteins.
C. Pizzimenti, V. Fiorentino, Mariausilia Franchina, M. Martini, G. Giuffrè, M. Lentini, N. Silvestris, Martina Di Pietro, Guido Fadda, G. Tuccari, A. Ieni   +10 more
semanticscholar   +1 more source

TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis [PDF]

, 2015
Truncating mutations in the tumor suppressor gene adenomatous polyposis coli (APC) are the initiating step in the vast majority of sporadic colorectal cancers, and they underlie familial adenomatous polyposis (FAP) syndromes.
Creytens, David, Geurs, Sarah, Naert, Thomas, Sanders, Ellen, Tran Thi, Hong, Van Imschoot, Griet, Van Nieuwenhuysen, Tom, Van Roy, Frans, Vleminckx, Kris   +8 more
core   +7 more sources

Is There Such a Thing as a Genuine Cancer Stem Cell Marker? Perspectives from the Gut, the Brain and the Dental Pulp

Biology, 2020
The conversion of healthy stem cells into cancer stem cells (CSCs) is believed to underlie tumor relapse after surgical removal and fuel tumor growth and invasiveness. CSCs often arise from the malignant transformation of resident multipotent stem cells,
Crende Olatz, García-Gallastegui Patricia, Luzuriaga Jon, Badiola Iker, de la Hoz Carmen, Unda Fernando, Ibarretxe Gaskon, Pineda Jose Ramon   +7 more
doaj   +1 more source

Human BCAS3 expression in embryonic stem cells and vascular precursors suggests a role in human embryogenesis and tumor angiogenesis. [PDF]

PLoS ONE, 2007
Cancer is often associated with multiple and progressive genetic alterations in genes that are important for normal development. BCAS3 (Breast Cancer Amplified Sequence 3) is a gene of unknown function on human chromosome 17q23, a region associated with ...
Kavitha Siva, Parvathy Venu, Anita Mahadevan, Shankar S K, Maneesha S Inamdar   +4 more
doaj   +1 more source

Theoretical foundations of studying criticality in the brain [PDF]

Theoretical foundations of studying criticality in the brain. Network Neuroscience 2022; 6 (4): 1148-1185, 2023
Criticality is hypothesized as a physical mechanism underlying efficient transitions between cortical states and remarkable information processing capacities in the brain. While considerable evidence generally supports this hypothesis, non-negligible controversies persist regarding the ubiquity of criticality in neural dynamics and its role in ...
arxiv   +1 more source