Results 51 to 60 of about 28,009 (230)

Thermo-mechanical contact problems and elastic behaviour of single and double sides functionally graded brake disks with temperature-dependent material properties

open access: yesScientific Reports, 2019
A thermo-elastic contact problem of functionally graded materials (FGMs) rotating brake disk with different pure brake pad areas under temperature dependent material properties is solved by Finite Element Method (FEM). The properties of brake disk change
Mehdi Bayat   +5 more
doaj   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

open access: yesAdvanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li   +5 more
wiley   +1 more source

The effects of porosity in friction performance of brake pad using waste tire dust

open access: yesPolímeros, 2015
This research is focused on the effect of porosity on the friction-wear properties of automotive brake pads. Waste Tire Dust (WTD) was used as a new friction material in brake pads. Newly formulated brake pad materials with five different components have
İbrahim Mutlu   +2 more
doaj   +1 more source

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

open access: yesAdvanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee   +11 more
wiley   +1 more source

Pengaruh Variasi Waktu Tahan Kompaksi Terhadap Performa Kampas Rem Dengan Matriks Phenolic Resin [PDF]

open access: yes, 2016
Brake pad is one component of a motor vehicle which serves to stop the vehicle speed motorcycle. When the rate of high-speed vehicle brake has an important role , even the safety of the rider depends on the quality of the brake lining .
, Ir. Bibit Sugito, MT.   +1 more
core  

The UT 19-channel DC SQUID based neuromagnetometer [PDF]

open access: yes, 1991
A l9-channel DC SQUID based neuromagnetometer is under construction at the University of Twente (UT). Except for the cryostat all elements of the system are developed at the UT.
Ancum, G.K. van   +6 more
core   +4 more sources

MODAL AND THERMAL-MECHANICAL COUPLING ANALYSIS INAUTOMOTIVE DISC BRAKE MECHANISM

open access: yesJixie qiangdu, 2017
Brake pad is vibrating when it is friction contact with the brake disc surface in automotive disc brake mechanism.When the vibration rate is close to its natural frequency of the material.
BI HouHuang   +3 more
doaj  

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

open access: yesAdvanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li   +25 more
wiley   +1 more source

Brake for rollable platform [PDF]

open access: yes, 1974
Frame-mounted brake is independent of wheels and consists of simple lever-actuated foot. Brake makes good contact with surface even though foot pad is at higher or lower level than wheels, this is particularly important when a rollable platform is used ...
Morris, A. L.
core   +1 more source

S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

open access: yesAdvanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng   +13 more
wiley   +1 more source

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