Results 51 to 60 of about 9,753 (239)

Single‐Cell Transcriptomics Reveals FLS2‐Dependent Hypoxia Signaling and ERF13‐Mediated Transcription During flg22‐Triggered Immunity

Advanced Science, EarlyView.
This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou, Aizhi Qin, Mengfan Li, Qianli Zhao, Luyao Kong, Lulu Yan, Chunyang Li, Hao Liu, Yinpeng Zhang, Jiani Long, Mengyu Liao, Mengmeng Zhou, Xiaoli Fan, Baozhen Wang, Wenxuan Kang, Shui Wang, Zhixin Liu, Xuwu Sun   +17 more
wiley   +1 more source

The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis

Advanced Science, EarlyView.
SLC39A13/ZIP13, a newly discovered intracellular iron transporter, delivers iron to the ER/Golgi to catalyze procollagen hydroxylation during collagen maturation. Here, we systematically characterize the cell type‐specific functions of ZIP13 across distinct hepatic cell populations, and identify hepatic stellate cell‐specific ZIP13 as a promising and ...
Shanshan Guo, Yalin Wang, Binyu Lu, Yu Zhang, David M. Frazer, Bing Zhou   +5 more
wiley   +1 more source

Application of Pneumatic Ventilated Disc Brake in Mine Electric Locomotive

Jixie chuandong, 2018
In order to improve the safety of underground transportation of mine electric locomotive,the existing hand wheel brake shoe brake device is analyzed.
Li Zhaosong, Zhang Yulu, Dong Mengshi
doaj  

Predictive Performance of Anti-Lock Braking System with PID Controller Optimized by Gravitational Search Algorithm for a Quarter Car Model: Simulation Modeling and Control

Automotive Experiences
Anti-lock Braking Systems (ABS) are critical safety components in the passenger vehicles. The ABS prevents wheel lock-up during braking and maintains vehicle control.
Mohd Sabirin Rahmat, Fauzi Ahmad, Vimal Rau Aparow, Rizauddin Ramli, Sallehuddin Mohamed Haris, Mohd Anas Mohd Sabri, Mohd Anas Mohd Sabri, Meor Iqram Meor Ahmad, Mohd Muhyidin Mustafa   +8 more
doaj   +1 more source

Characteristic Analysis of the Peak Braking Force and the Critical Speed of Eddy Current Braking in a High-Speed Maglev

Energies, 2019
In the eddy current braking system of high-speed maglev, the peak braking force and the critical speed are key factors determining the performance of eddy current braking force.
Chuntao Chen, Jie Xu, Xibo Yuan, Xinzhen Wu   +3 more
doaj   +1 more source

The Impact of Physical Motion Cues on Driver Braking Performance: A Clinical Study Using Driving Simulator and Eye Tracker. [PDF]

Sensors (Basel), 2022
El Hamdani S, Bouchner P, Kunclova T, Lehet D.   +3 more
europepmc   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Research on the Maximum Disc Surface Temperature and Thermal-mechanical Coupling Characteristics of Train Brake Pair

Journal of Harbin University of Science and Technology
The high temperature generated by train braking affects the mechanical properties of the brake materials, and there is an interaction between them, affecting the braking performance of the train.
YU Chunyu, LI Weipu, GUO Yang, HONG Fanli, ZHANG Qinghai, GAO Jianwei   +5 more
doaj   +1 more source

Caspase‐3/GSDME‐Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early‐Onset Preeclampsia

Advanced Science, EarlyView.
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang, Weinan Deng, Shilei Bi, Yifan Wang, Zhaowei Tu, Lijun Huang, Lili Du, Lizi Zhang, Zhoushan Feng, Wei Sun, Tengfei Liu, Julia Kzhyshkowska, Haibin Wang, Jingsi Chen, Dunjin Chen, Shuang Zhang   +15 more
wiley   +1 more source

Effect of Friction Model and Tire Maneuvering on Tire-Pavement Contact Stress

Advances in Materials Science and Engineering, 2015
This paper aims to simulate the effects of different friction models on tire braking. A truck radial tire (295/80R22.5) was modeled and the model was validated with tire deflection. An exponential decay friction model that considers the effect of sliding
Haichao Zhou, Guolin Wang, Yangmin Ding, Jian Yang, Chen Liang, Jing Fu   +5 more
doaj   +1 more source