Results 81 to 90 of about 9,753 (239)

Illuminating Mitochondrial RNA G‐Quadruplexes as Structural Brakes on RNA Granule Assembly and OXPHOS

Advanced Science, EarlyView.
A new fluorescent probe, MitoQUMA, brings mitochondrial RNA G‐quadruplexes (mtRNA G4s) into view in live cells. This tool reveals that excessive mtRNA G4 formation halts mitochondrial RNA granule (MRG) assembly, opposite to the phase‐separation role of cytoplasmic RNA G4s. A chemical genetic screen further identifies a Wnt/β‐catenin–GRSF1–mtRNA G4 axis
Gui‐Xue Tang, Jia‐Tong Yan, Mao‐Lin Li, Cui Zhou, Jian Wang, Shuo‐Bin Chen, Zhi‐Shu Huang, Jia‐Heng Tan   +7 more
wiley   +1 more source

Transcriptomic and Neuroimaging Decoding of Brain‐Immune Crosstalk in Thyroid Eye Disease

Advanced Science, EarlyView.
This study employed an imaging transcriptomics framework integrating resting‐state fMRI with Allen Human Brain Atlas transcriptomic data, coupled with peripheral blood RNA sequencing, to decode brain‐immune crosstalk in thyroid eye disease. Frontal, parietal, subcortical, and brainstem regions were identified as key neuroimmune‐ vulnerable regions ...
Haiyang Zhang, Yuting Liu, Shufan Jiang, Zilin Fang, Mengda Jiang, Xiaofeng Tao, Tianyi Zhu, Jipeng Li, Sijie Fang, Xuefei Song, Yinwei Li, Jing Sun, Chuanjun Tong, Zhengrun Gao, Huifang Zhou, Xianqun Fan   +15 more
wiley   +1 more source

Dorsal Raphe VIP Neurons Are Critical for Survival‐Oriented Vigilance

Advanced Science, EarlyView.
DRNVIP neurons in mice and primates are strategically positioned to influence the central extended amygdala via feedback loops. They regulate the excitability of PKC‐δ neurons in the ovBNST and CeA through glutamate release. Their ablation heightens activity in these regions, disrupts active‐phase sleep architecture, enhances risk assessment behaviors ...
Adriane Guillaumin, Emma Perrot, Thibault Dhellemmes, Laura Boi, Daniel De Castro Medeiros, Christelle Glangetas, Sylvie Dumas, Sandra Dovero, Nathalie Biendon, Elodie Ladeveze, Maëlle Hardel, Marc Landry, Erwan Bezard, Jérôme Baufreton, Gilberto Fisone, François Georges   +15 more
wiley   +1 more source

Braking Performance Analysis of Heavy Haul Combined Train in Different Vehicle Marshalling Modes

机车电传动, 2016
The time for brake command reception/transmission, train braking/release, and train charging differed as the locomotive position changes in heavy haul combined train, based on analyzing the effect of vehicle marshalling mode on performance for the 20 000
LIU Quan, FANG Changzheng, LUO Zhixun
doaj  

Thermally Programmable Two‐Port Non‐Hermitian Acoustic Metastructure for Broadband and Direction‐Dependent Absorption

Advanced Science, EarlyView.
A thermally programmable two‐port non‐Hermitian acoustic metastructure is presented, where temperature acts as a non‐geometric tuning variable. Thermal modulation reconfigures impedance matching and loss‐leakage coupling, enabling exceptional‐point driven, broadband, and direction‐dependent sound absorption without requiring geometric reconfiguration ...
Zichao Guo, Zhendong Li, Ziping Lei, Zirui Yang, Kexin Zeng, Zheng Fan, Zhonggang Wang   +6 more
wiley   +1 more source

Automation of Surgical Workflow Recognition: Unveiling the Surgical Instrument Kinematics that Underly Robot‐Assisted Prostatectomy Procedures

Advanced Intelligent Discovery, EarlyView.
Automated procedural analysis is recognized as one of the major game changers for robotic surgery. Meaning digital analysis needs to replace the manual assessments that set todays standard. Mechanical robotic‐instrument tracking enables the derivation of quantitative kinematic metrics that support behavior‐based workflow segmentation into distinct ...
Kateryna Pirkovets, Matthias N. van Oosterom, Vera A. Ottens, Henk G. van der Poel, Fijs W. B. van Leeuwen   +4 more
wiley   +1 more source

Research on Braking Force Distribution Strategy for Race Cars Based on PID Algorithm

World Electric Vehicle Journal
This study proposes a dynamic braking force distribution strategy based on a PID algorithm for Formula Student electric racing cars, addressing the limitations of fixed-ratio distribution methods in adapting to dynamic braking conditions.
Jigang Liu, Yingfeng Hua, Zhicheng Zhou, Yushuo Pan   +3 more
doaj   +1 more source

A Miniature Rotary Electrostatic Clutch for Assigning Multi‐Degrees of Freedom to Insect‐Scale Robots

Advanced Intelligent Systems, EarlyView.
Insect‐scale crawling robots can traverse confined environments; nevertheless, their functionalities are predominantly restricted to sensing because of challenges in integrating actuated degrees of freedom. Herein, a miniature rotary electrostatic clutch is presented by incorporating cutting patterns in the clutch layer.
Jongeun Lee, Amir Firouzeh, Seunghyun An, Pilwoo Lee, Kyu‐Jin Cho   +4 more
wiley   +1 more source

Technical Discussion on Urban Rail Transit Electromechanical Braking System

Chengshi guidao jiaotong yanjiu
[Objective] To gain a better understanding of the development prospect of electromechanical braking system, application of the system in urban rail transit is taken as the research subject for technical discussion.
MU Beiyao, FAN Guixin, ZHANG Xiang, CHEN Qian, GAO Tianyang   +4 more
doaj   +1 more source

REWW‐ARM—Remote Wire‐Driven Mobile Robot: Design, Control, and Experimental Validation

Advanced Intelligent Systems, EarlyView.
The Remote Wire‐Driven robot “REWW‐ARM” demonstrates a new concept of remote actuation that separates electronics from harsh environments while retaining closed‐loop control. Combining tendon‐sheath mechanisms with decoupled joints, it achieves efficient power transmission and autonomous locomotion, manipulation, and underwater operation, suggesting ...
Takahiro Hattori, Kento Kawaharazuka, Temma Suzuki, Keita Yoneda, Kei Okada   +4 more
wiley   +1 more source