Results 1 to 10 of about 67,993 (243)

Branched chain amino acids prime metabolic inflammation [PDF]

Molecular Metabolism
Sterile inflammation is associated with a broad range of metabolic stressors including both dietary excess and prolonged fasting. In a 10-day human fasting study, we previously identified a surge in the circulating inflammatory biomarker, C-reactive ...
Nandini K. Doshi, Tristan Pesaresi, Trishya Pagadala, William Dion, Yang Zhang, Natalie L. David, Tânia Amorim, Wenjia Wang, G.V. Naveen Kumar, Bokai Zhu, Silvia Liu, Parth Patwari, Pouneh K. Fazeli, Matthew L. Steinhauser   +13 more
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Primary Roles of Branched Chain Amino Acids (BCAAs) and Their Metabolism in Physiology and Metabolic Disorders [PDF]

Molecules
Leucine, isoleucine, and valine are collectively known as branched chain amino acids (BCAAs) and are often discussed in the same physiological and pathological situations.
Tomoki Bo, Junichi Fujii
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Research progress on branched-chain amino acid aminotransferases

Frontiers in Genetics, 2023
Branched-chain amino acid aminotransferases, widely present in natural organisms, catalyze bidirectional amino transfer between branched-chain amino acids and branched-chain α-ketoacids in cells.
Can Chen, Hassan Naveed, Hassan Naveed, Keping Chen   +3 more
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Branched Chain Amino Acids [PDF]

Annual Review of Physiology, 2019
Branched chain amino acids (BCAAs) are building blocks for all life-forms. We review here the fundamentals of BCAA metabolism in mammalian physiology. Decades of studies have elicited a deep understanding of biochemical reactions involved in BCAA catabolism.
Michael, Neinast, Danielle, Murashige, Zoltan, Arany   +2 more
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Branched‐chain amino acids [PDF]

Journal of Gastroenterology and Hepatology, 2000
AbstractThe branched‐chain amino acids (BCAA), isoleucine, leucine and valine, are unique in that they are principally metabolized extrahepatically in the skeletal muscle. This observation led to the investigation of these nutrients in a number of clinical scenarios.
C, Platell, S E, Kong, R, McCauley, J C, Hall   +3 more
openaire   +2 more sources

Circulating branch chain amino acids and improvement in liver fat content in response to exercise interventions in NAFLD

Scientific Reports, 2021
Nonalcoholic fatty liver disease is likely to be associated with increased circulating branched-chain amino acids. We investigated the relationship between changes in branched-chain amino acids levels in the serum and improvement in liver fat content ...
Xiulin Shi, Hongyan Yin, Jia Li, Caoxin Huang, Yinling Chen, Zheng Chen, Wei Liu, Weijuan Su, Yiping Zhang, Mingzhu Lin, Yan Zhao, Xuejun Li   +11 more
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Branched chain amino acids metabolism in heart failure

Frontiers in Nutrition, 2023
As a terminal stage of various cardiovascular diseases, heart failure is of great concern due to its high mortality rate and limited treatment options.
Chenshan Gao, Lei Hou, Lei Hou
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The biological functions and metabolic pathways of valine in swine

Journal of Animal Science and Biotechnology, 2023
Valine is an essential amino acid and a type of branched-chain amino acid. Due to the involvement of branched-chain amino acids in various metabolic pathways, there has been a surge of interests in valine nutrition and its role in animal physiology.
Chuni Wang, Yao Peng, Yiru Zhang, Juan Xu, Sheng Jiang, Leli Wang, Yulong Yin   +6 more
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Amino acid accumulation limits the overexpression of proteins in Lactococcus lactis. [PDF]

PLoS ONE, 2010
BACKGROUND: Understanding the biogenesis pathways for the functional expression of recombinant proteins, in particular membrane proteins and complex multidomain assemblies, is a fundamental issue in cell biology and of high importance for future progress
Ravi K R Marreddy, Eric R Geertsma, Hjalmar P Permentier, Joao P C Pinto, Jan Kok, Bert Poolman   +5 more
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Production of d-Branched-Chain Amino Acids by Lactic Acid Bacteria Carrying Homologs to Isoleucine 2-Epimerase of Lactobacillus buchneri

Frontiers in Microbiology, 2018
Isoleucine 2-epimerase (ILEP) is a novel branched-chain amino acid racemase isolated from Lactobacillus buchneri. In this study, we examined production of free d-branched-chain amino acids such as d-valine, d-leucine, and d-allo-isoleucine, using lactic ...
Yuta Mutaguchi, Kano Kasuga, Ikuo Kojima
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