Results 11 to 20 of about 148,302 (300)

Xenogeneic, extracorporeal liver perfusion in primates improves the ratio of branched-chain amino acids to aromatic amino acids (Fischer's ratio) [PDF]

, 1999
In fulminant hepatic failure (FHF), the development of hepatic encephalopathy is associated with grossly abnormal concentrations of plasma amino acids (PAA).
Hammer, C., Heil, W., Lemmens, H.-P., Matthes, M., Neuhaus, P., Padval, D., Puhl, G., Schön, M. R.   +7 more
core   +1 more source

Amino acid accumulation limits the overexpression of proteins in Lactococcus lactis. [PDF]

PLoS ONE, 2010
BACKGROUND: Understanding the biogenesis pathways for the functional expression of recombinant proteins, in particular membrane proteins and complex multidomain assemblies, is a fundamental issue in cell biology and of high importance for future progress
Ravi K R Marreddy, Eric R Geertsma, Hjalmar P Permentier, Joao P C Pinto, Jan Kok, Bert Poolman   +5 more
doaj   +1 more source

An approach to nutritional therapy of hepatic encephalopathy by normalization of deranged amino acid patterns in serum [PDF]

, 1978
A mixture with essential and nonessential amino acids high in branched chain amino acids and low in aromatic amino acids (Fischer solution), and another synthetic mixture of branched chain amino acids containing 3 amino acids associated with the urea ...
Higashi, Toshihiro, Nagashima, Hideo, Watanabe, Akiharu   +2 more
core   +1 more source

Production of d-Branched-Chain Amino Acids by Lactic Acid Bacteria Carrying Homologs to Isoleucine 2-Epimerase of Lactobacillus buchneri

Frontiers in Microbiology, 2018
Isoleucine 2-epimerase (ILEP) is a novel branched-chain amino acid racemase isolated from Lactobacillus buchneri. In this study, we examined production of free d-branched-chain amino acids such as d-valine, d-leucine, and d-allo-isoleucine, using lactic ...
Yuta Mutaguchi, Kano Kasuga, Ikuo Kojima
doaj   +1 more source

Immunometabolism – The Role of Branched-Chain Amino Acids

Frontiers in Immunology, 2022
Immunometabolism has been the focus of extensive research over the last years, especially in terms of augmenting anti-tumor immune responses. Regulatory T cells (Tregs) are a subset of CD4+ T cells, which have been known for their immunosuppressive roles
Berkay Yahsi, Gurcan Gunaydin
doaj   +1 more source

Pancreatic hormones and amino acid levels following liver transplantation [PDF]

, 1987
Glucose intolerance, hyperinsulinemia, peripheral insulin resistance and hyperglucagonemia are common in patients with advanced liver disease. These abnormalities in the plasma levels of the pancreatic hormones, insulin and glucagon have been thought to ...
Chisholm, Collins, Collins, Conn, Creutzfeldt, Dudley, Eriksson, Fath, Fischer, Hahn, Hamish, Johnston, Kam, Kenny, Limberg, Marchesini, Marchesini, Marchesini, Marchesini, Megysi, Morgan, Muller, Nielsen, Pearly, Reilly, Robertson, Schander, Sherwin, Sherwin, Soeters, Starzl, Starzl, Trinder   +32 more
core   +1 more source

Dataset describing the amino acid catabolism of Thermoanaerobacter strain AK85: The influence of culture conditions on end product formation

Data in Brief, 2019
The dataset describes the catabolism of the 20 proteogenics amino acids and their end products by Thermoanaerobacter strain AK85 under different electron scavenging conditions with an emphasis on the branched-chain amino acids as reported in Scully and ...
Sean Michael Scully, Johann Orlygsson
doaj   +1 more source

Production and characterization of murine models of classic and intermediate maple syrup urine disease [PDF]

, 2006
Background Maple Syrup Urine Disease (MSUD) is an inborn error of metabolism caused by a deficiency of branched-chain keto acid dehydrogenase. MSUD has several clinical phenotypes depending on the degree of enzyme deficiency.
Gregg E Homanics, Kristen Skvorak, Carolyn Ferguson, Simon Watkins, Harbhajan S Paul, D Chuang, L Marshall, S Yeaman, M Yoshino, H Paul, R Paxton, F Peinemann, DH Morton, R Cox, DJ Danner, BS Khatra, A Suryawan, A Bodner-Leidecker, JC Netter, U Wendel, KA Strauss, PA Harper, B Zhang, JD Baird, J-Y Wu, SL Mansour, V Tybulewicz, A Nagy, GE Homanics, M Gossen, RL Brinster, RD Palmiter, M Kozak, GE Homanics, SM Hutson, H Paul, GW Snedecor, A Harper, A Kistner, A Mattevi, JE Knapp, DT Chuang, L Wang, S Mochizuki, GM Mueller, H Koyata, G Ambrosino, M Muraca, JH Fair, J Chuang, J Li   +50 more
core   +1 more source

Ammonia toxicity to the brain and creatine. [PDF]

, 2004
Symptoms of hyperammonemia are age-dependent and some are reversible. Multiple mechanisms are involved. Hyperammonemia increases the uptake of tryptophan into the brain by activation of the L-system carrier while brain glutamine plays a still undefined ...
Bachmann, C., Boulat, O., Braissant, O., Henry, H., Villard, A.M.   +4 more
core   +1 more source

BCKDK of BCAA Catabolism Cross-talking With the MAPK Pathway Promotes Tumorigenesis of Colorectal Cancer

EBioMedicine, 2017
Branched-chain amino acids catabolism plays an important role in human cancers. Colorectal cancer is the third most commonly diagnosed cancer in males and the second in females, and the new global incidence is over 1.2 million cases. The branched-chain α-
Peipei Xue, Fanfan Zeng, Qiuhong Duan, Juanjuan Xiao, Lin Liu, Ping Yuan, Linni Fan, Huimin Sun, Olesya S. Malyarenko, Hui Lu, Ruijuan Xiu, Shaoqing Liu, Chen Shao, Jianmin Zhang, Wei Yan, Zhe Wang, Jianyong Zheng, Feng Zhu   +17 more
doaj   +1 more source