Results 21 to 30 of about 2,748,091 (304)

Branched-Chain Amino Acids and Immunity , [PDF]

The Journal of Nutrition, 2006
Although there has been great interest in the effects of amino acids on immune function, little is known about the impact of changes in BCAA availability on the ability of the immune system to function. Human immune cells incorporate BCAA into proteins and are able to oxidize BCAA.
openaire   +2 more sources

BCKDK of BCAA Catabolism Cross-talking With the MAPK Pathway Promotes Tumorigenesis of Colorectal Cancer

EBioMedicine, 2017
Branched-chain amino acids catabolism plays an important role in human cancers. Colorectal cancer is the third most commonly diagnosed cancer in males and the second in females, and the new global incidence is over 1.2 million cases. The branched-chain α-
Peipei Xue, Fanfan Zeng, Qiuhong Duan, Juanjuan Xiao, Lin Liu, Ping Yuan, Linni Fan, Huimin Sun, Olesya S. Malyarenko, Hui Lu, Ruijuan Xiu, Shaoqing Liu, Chen Shao, Jianmin Zhang, Wei Yan, Zhe Wang, Jianyong Zheng, Feng Zhu   +17 more
doaj   +1 more source

Plasma Amino Acid Concentrations Predict Mortality in Patients with End-Stage Liver Disease. [PDF]

PLoS ONE, 2016
The liver plays a key role in amino acid metabolism. In former studies, a ratio between branched-chain and aromatic amino acids (Fischer's ratio) revealed associations with hepatic encephalopathy.
Benedict Kinny-Köster, Michael Bartels, Susen Becker, Markus Scholz, Joachim Thiery, Uta Ceglarek, Thorsten Kaiser   +6 more
doaj   +1 more source

The Effect of Amino Acids on Production of SCFA and bCFA by Members of the Porcine Colonic Microbiota

Microorganisms, 2022
Functional amino acids supplementation to farm animals is considered to not only be beneficial by regulating intestinal barrier, oxidative stress, and immunity, but potentially also by impacting the gut microbiota.
Pieter Van den Abbeele, Jonas Ghyselinck, Massimo Marzorati, Anna-Maria Koch, William Lambert, Joris Michiels, Tristan Chalvon-Demersay   +6 more
doaj   +1 more source

Disorders of branched chain amino acid metabolism

Translational Science of Rare Diseases, 2016
The three essential branched-chain amino acids (BCAAs), leucine, isoleucine and valine, share the first enzymatic steps in their metabolic pathways, including a reversible transamination followed by an irreversible oxidative decarboxylation to coenzyme-A derivatives.
Manoli, I., Venditti, C.P.
openaire   +3 more sources

Genome-wide association studies reveal the genetic basis of amino acid content variation in tea plants

Journal of Integrative Agriculture, 2023
Tea is one of the most popular non-alcoholic beverages in the world, and free amino acids, especially theanine, make a major contribution to the umami taste of tea.
Ya-fei GUO, Dai-li LI, Hai-ji QIU, Xiao-liang ZHANG, Lin LIU, Jing-jing ZHAO, De-yuan JIANG   +6 more
doaj   +1 more source

The catalytic subunit of the system L1 amino acid transporter (Slc7a5) facilitates nutrient signalling in mouse skeletal muscle [PDF]

, 2014
The System L1-type amino acid transporter mediates transport of large neutral amino acids (LNAA) in many mammalian cell-types. LNAA such as leucine are required for full activation of the mTOR-S6K signalling pathway promoting protein synthesis and cell ...
Adel F M Ibrahim, Yun-Bo Shi, Mitchell, Fiona E., Grant English (527945), Peter M Taylor, Taylor Peter M., Poncet, Nadège, Fiona E Mitchell, Ibrahim Adel F. M., English, Grant, J. Simon C Arthur (527946), Nadège Poncet, Victoria A McGuire, Yun-Bo Shi (193634), Arthur J. Simon C, McGuire Victoria A., Adel F. M. Ibrahim (188343), Grant English, Taylor, Peter M., Ibrahim, Adel F. M., Poncet Nadège, Nadège Poncet (527942), Victoria A. McGuire (527944), Peter M. Taylor (527947), McGuire, Victoria A., English Grant, Arthur, J. Simon C; id_orcid, Mitchell Fiona E., Shi Yun-Bo, Fiona E. Mitchell (527943), Shi, Yun-Bo, J Simon C Arthur   +31 more
core   +1 more source

Postprandial Glucose and Gastrointestinal Hormone Responses of Healthy Subjects to Wheat Biscuits Enriched with L-Arginine or Branched-Chain Amino Acids of Plant Origin

, 2022
The study investigates the effects of wheat biscuits supplemented with plant flours originating from legumes/seeds enriched either in L-arginine (L-arg) or branched-chain amino acids (BCAAs) on postprandial glucose response of healthy subjects ...
Stamatia Simati, Kokkinos, Alexander, Maria Halabalaki, Konstantopoulos, Panagiotis, Panagiotis Konstantopoulos, Yanni, Amalia E., Alexander Kokkinos, Amalia E. Yanni, Simati, Stamatia, Vaios T. Karathanos, Varvara Papaioannou, Karathanos, Vaios T., Halabalaki, Maria, Panagiota Binou, Papaioannou, Varvara, Binou, Panagiota   +15 more
core   +1 more source

Setting the Stage for Branched-Chain Amino Acids Use in Neurological Pathologies: Does a Single Oral Dose Provide Hours of Elevated Systemic Levels?

Diseases
Background: Recent studies have demonstrated that branched-chain amino acids are neuroprotective and neurorestorative. Branched-chain amino acid supplements are now being recommended to be taken before contact sports to reduce concussions.
Ezek Mathew, Nathan Jones, McKinley Dews, Dominique Neal, Anders Cohen   +4 more
doaj   +1 more source

Neutrophils as a source of branched-chain, aromatic and positively charged free amino acids

Cell Adhesion & Migration, 2019
Neutrophils release branched-chain (valine, isoleucine, leucine), aromatic (tyrosine, phenylalanine) and positively charged free amino acids (arginine, ornithine, lysine, hydroxylysine, histidine) when adhere and spread onto fibronectin.
Svetlana I. Galkina, Natalia V. Fedorova, Alexander L. Ksenofontov, Vladimir I. Stadnichuk, Ludmila A. Baratova, Galina F. Sud’Ina   +5 more
doaj   +1 more source