Results 181 to 190 of about 67,993 (243)

“More” Artificial mRNAs: Beyond the Art of Nature

open access: yesAdvanced Science, EarlyView.
Inspired by nature yet transcending it, synthetic mRNA is being redesigned beyond the canonical architecture. This review highlights emerging forms—circular, branched, and self‐amplifying mRNAs—that expand stability, persistence, and functional control, illustrating how artificial mRNA is evolving into a new medium for programmable biological ...
Yuanzhe Cui   +3 more
wiley   +1 more source

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

open access: yesAdvanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang   +12 more
wiley   +1 more source

Dietary Branched-Chain Amino Acids Modify Postinfarct Cardiac Remodeling and Function in the Murine Heart. [PDF]

open access: yesJ Am Heart Assoc
Nguyen DC   +8 more
europepmc   +1 more source

Combining Electrochemical Reduction with Biosynthesis for Directed Conversion of CO2 into a Library of C3 Chemicals

open access: yesAdvanced Science, EarlyView.
In the H‐type electrolytic cell, carbon dioxide is reduced to acetic acid via electro‐microbial catalysis. The simply processed acetic acid is further converted through biological fermentation into high‐value‐added products, including acrylic acid, L‐lactic acid, and β‐alanine.
Kaixing Xiao   +8 more
wiley   +1 more source

2D Metal‐Organic Frameworks for High‐Performance Solid‐State Electrolytes: A Comprehensive Review

open access: yesAdvanced Science, EarlyView.
In this review, we elucidate the intrinsic advantages, synthetic methodologies, structural characteristics, ion‐transport mechanisms and performance optimization strategies while highlighting representative material systems and applications of 2D MOFs for electrolyte applications.
Changchun Ai   +8 more
wiley   +1 more source

Branched-chain amino acids contribute to diabetic kidney disease progression via PKM2-mediated podocyte metabolic reprogramming and apoptosis. [PDF]

open access: yesNat Commun
Zhao H   +23 more
europepmc   +1 more source

Interfacial Engineering in Rare‐Earth Oxide/ZnO Heterojunctions for High‐Performance Trimethylamine Sensing and Fish Freshness Monitoring

open access: yesAdvanced Science, EarlyView.
This study realizes superior gas sensing performance via Yb2O3/ZnO heterojunction design, achieving highly sensitive/selective trimethylamine detection at room temperature while elucidating the intrinsic sensing mechanism. This innovation is applied to reliable real‐time fish freshness monitoring, paving a feasible way for translating advanced material
Junxi Cheng   +5 more
wiley   +1 more source

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