Results 11 to 20 of about 67,993 (243)

Immunometabolism – The Role of Branched-Chain Amino Acids

Frontiers in Immunology, 2022
Immunometabolism has been the focus of extensive research over the last years, especially in terms of augmenting anti-tumor immune responses. Regulatory T cells (Tregs) are a subset of CD4+ T cells, which have been known for their immunosuppressive roles
Berkay Yahsi, Gurcan Gunaydin
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Dataset describing the amino acid catabolism of Thermoanaerobacter strain AK85: The influence of culture conditions on end product formation

Data in Brief, 2019
The dataset describes the catabolism of the 20 proteogenics amino acids and their end products by Thermoanaerobacter strain AK85 under different electron scavenging conditions with an emphasis on the branched-chain amino acids as reported in Scully and ...
Sean Michael Scully, Johann Orlygsson
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BCKDK of BCAA Catabolism Cross-talking With the MAPK Pathway Promotes Tumorigenesis of Colorectal Cancer

EBioMedicine, 2017
Branched-chain amino acids catabolism plays an important role in human cancers. Colorectal cancer is the third most commonly diagnosed cancer in males and the second in females, and the new global incidence is over 1.2 million cases. The branched-chain α-
Peipei Xue, Fanfan Zeng, Qiuhong Duan, Juanjuan Xiao, Lin Liu, Ping Yuan, Linni Fan, Huimin Sun, Olesya S. Malyarenko, Hui Lu, Ruijuan Xiu, Shaoqing Liu, Chen Shao, Jianmin Zhang, Wei Yan, Zhe Wang, Jianyong Zheng, Feng Zhu   +17 more
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Branched-Chain Amino Acids and Branched-Chain Keto Acids in Hyperammonemic States: Metabolism and as Supplements

Metabolites, 2020
In hyperammonemic states, such as liver cirrhosis, urea cycle disorders, and strenuous exercise, the catabolism of branched-chain amino acids (BCAAs; leucine, isoleucine, and valine) is activated and BCAA concentrations decrease.
Milan Holeček
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Plasma Amino Acid Concentrations Predict Mortality in Patients with End-Stage Liver Disease. [PDF]

PLoS ONE, 2016
The liver plays a key role in amino acid metabolism. In former studies, a ratio between branched-chain and aromatic amino acids (Fischer's ratio) revealed associations with hepatic encephalopathy.
Benedict Kinny-Köster, Michael Bartels, Susen Becker, Markus Scholz, Joachim Thiery, Uta Ceglarek, Thorsten Kaiser   +6 more
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The Effect of Amino Acids on Production of SCFA and bCFA by Members of the Porcine Colonic Microbiota

Microorganisms, 2022
Functional amino acids supplementation to farm animals is considered to not only be beneficial by regulating intestinal barrier, oxidative stress, and immunity, but potentially also by impacting the gut microbiota.
Pieter Van den Abbeele, Jonas Ghyselinck, Massimo Marzorati, Anna-Maria Koch, William Lambert, Joris Michiels, Tristan Chalvon-Demersay   +6 more
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Genome-wide association studies reveal the genetic basis of amino acid content variation in tea plants

Journal of Integrative Agriculture, 2023
Tea is one of the most popular non-alcoholic beverages in the world, and free amino acids, especially theanine, make a major contribution to the umami taste of tea.
Ya-fei GUO, Dai-li LI, Hai-ji QIU, Xiao-liang ZHANG, Lin LIU, Jing-jing ZHAO, De-yuan JIANG   +6 more
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Setting the Stage for Branched-Chain Amino Acids Use in Neurological Pathologies: Does a Single Oral Dose Provide Hours of Elevated Systemic Levels?

Diseases
Background: Recent studies have demonstrated that branched-chain amino acids are neuroprotective and neurorestorative. Branched-chain amino acid supplements are now being recommended to be taken before contact sports to reduce concussions.
Ezek Mathew, Nathan Jones, McKinley Dews, Dominique Neal, Anders Cohen   +4 more
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Neutrophils as a source of branched-chain, aromatic and positively charged free amino acids

Cell Adhesion & Migration, 2019
Neutrophils release branched-chain (valine, isoleucine, leucine), aromatic (tyrosine, phenylalanine) and positively charged free amino acids (arginine, ornithine, lysine, hydroxylysine, histidine) when adhere and spread onto fibronectin.
Svetlana I. Galkina, Natalia V. Fedorova, Alexander L. Ksenofontov, Vladimir I. Stadnichuk, Ludmila A. Baratova, Galina F. Sud’Ina   +5 more
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Leucinosis, or maple syrup urine disease (lecture and a clinical case)

Alʹmanah Kliničeskoj Mediciny, 2020
Maple syrup urine disease (leucinosis, short-chain ketoaciduria, branched-chain disease, branched-chain ketonuria) is an autosomal recessive disorder which is a consequence of the deficient branched-chain alpha ketoacid dehydrogenase complex.
Ju. A. Tsareva, N. I. Zryachkin, M. A. Kuznetsova, E. V. Bogacheva   +3 more
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