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Branched-Chain Amino Acids and Brain Metabolism

Neurochemical Research, 2017
This review aims to provide a historical reference of branched-chain amino acid (BCAA) metabolism and provide a link between peripheral and central nervous system (CNS) metabolism of BCAAs. Leucine, isoleucine, and valine (Leu, Ile, and Val) are unlike most other essential amino acids (AA), being transaminated initially in extrahepatic tissues, and ...
Justin E, Sperringer   +2 more
openaire   +2 more sources

Transaminase of Branched Chain Amino Acids*

The Journal of Biochemistry, 1968
Kenji Aki, Koichi Ogawa, Akira Ichihara
openaire   +1 more source

[The branched-chain amino acids].

Minerva gastroenterologica e dietologica, 2006
Branched-chain amino acids (BCAA: leucine, isoleucine and valine) are not just structural constituents of proteins, but have ''pharmacologic'' properties, known for several years: BCAA are catabolized mainly in muscle; can be oxidized with energy production, being nitrogen donors for other amino acids; regulate protein synthesis and degradation ...
C, Chiarla   +3 more
openaire   +1 more source

Branched-chain amino acids for hepatic encephalopathy

2003
Hepatic encephalopathy may be caused by a decreased plasma ratio of branched-chain amino acids (BCAA) to aromatic amino acids. Treatment with BCAA may therefore have a beneficial effect on patients with hepatic encephalopathy.To evaluate the beneficial and harmful effects of BCAA for patients with hepatic encephalopathy.We identified trials through The
B, Als-Nielsen   +3 more
openaire   +2 more sources

Branched chain amino acids in heptatic encephalopathy

The American Journal of Surgery, 2002
Early theories or hepatic encephalopathy focused on ammonia-driven disruption of the Krebs cycle and cellular energy production. The "false-neurotransmitter" theory directed attention toward the interactions of amino acids, metabolism, the blood-brain barrier and neurotransmission.
openaire   +2 more sources

Brain metabolism of branched-chain amino acids

Glia, 1997
The synthesis of brain glutamate requires an amino group donor that is efficiently transported into the brain and that is readily transaminated. The branched-chain amino acids (BCAA), particularly leucine, play this important role. The uptake of leucine across the blood-brain barrier is faster than any other amino acid.
openaire   +2 more sources

[Branched chain amino acid diseases].

Acta medica portuguesa, 1999
The authors present 19 cases of branched-chain AA catabolism disease: 9 Maple Syrup Urine Diseases, 6 Methylmalonic Acidemias, 2 Propionic Acidemias, 1 case of 3-OH-3-methylglutaryl-CoA-lyase deficiency and another of 2-methyl-ketoacetyl-CoA-thiolase deficiency. Fifteen are early neonatal forms and in 4 the onset occurred later. Fifteen patients (78.9%)
A, Cabral   +5 more
openaire   +1 more source

Amino Acids | Branched-Chain Amino Metabolism

2021
Elitsa A. Ananieva, Myra E. Conway
openaire   +1 more source

Branch-chain amino acids

Critical Care Medicine, 1990
B, Skeie   +5 more
openaire   +2 more sources

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