Results 211 to 220 of about 70,347 (257)
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Branched-Chain Amino Acids

2016
Branched-chain amino acids (BCAAs), viz., L-isoleucine, L-leucine, and L-valine, are essential amino acids that cannot be synthesized in higher organisms and are important nutrition for humans as well as livestock. They are also valued as synthetic intermediates for pharmaceuticals.
Keisuke, Yamamoto   +2 more
openaire   +3 more sources

Branched-Chain Amino Acid Metabolism

Annual Review of Nutrition, 1984
INTRODUCTION . . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 1 0 METABOLISM O F BRANCHED·CHAIN AMINO ACIDS (BCAA) AND BRANCHED·CHAIN Q·KETOACIDS (BCKA) . . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . .
A E, Harper, R H, Miller, K P, Block
openaire   +2 more sources

Branched-chain amino acids in disease

Science, 2019
Are BCAAs a biomarker, causal agent, or both in cardiometabolic disease?
Phillip J, White, Christopher B, Newgard
openaire   +2 more sources

Regulation of branched-chain amino acid metabolism and pharmacological effects of branched-chain amino acids

Hepatology Research, 2004
Significant evidence of the pharmacological and physiological effects of branched-chain amino acids (BCAA) has accumulated, attracting the interest of not only clinicians but also basic medical researchers. We summarize here the characteristic features of BCAA catabolism, focusing on the initial two enzymes in the pathway, branched-chain ...
Yoshiharu, Shimomura   +7 more
openaire   +2 more sources

Branch chain amino acids

Current Opinion in Clinical Nutrition and Metabolic Care, 2013
There is burgeoning evidence that branch chain amino acids (BCAAs) are biomarkers of metabolic, cardiovascular, renal and cerebrovascular disease. The purpose of this review is to summarize the current evidence in this area.Recent evidence demonstrates that BCAAs are associated with insulin resistance, type 2 diabetes, risk of cardiovascular disease ...
Bryan C, Batch   +2 more
openaire   +2 more sources

Branched-chain amino acids in cardiovascular disease

Nature Reviews Cardiology, 2022
Research conducted in the past 15 years has yielded crucial insights that are reshaping our understanding of the systems physiology of branched-chain amino acid (BCAA) metabolism and the molecular mechanisms underlying the close relationship between BCAA homeostasis and cardiovascular health. The rapidly evolving literature paints a complex picture, in
Robert W. McGarrah, Phillip J. White
openaire   +2 more sources

Branched-chain amino acid biosynthesis in fungi

Essays in Biochemistry, 2023
Abstract Branched-chain amino acids (BCAAs)—isoleucine, leucine, and valine—are synthesized by fungi. These amino acids are important components of proteins and secondary metabolites. The biochemical pathway for BCAA biosynthesis is well-characterized in the yeast Saccharomyces cerevisiae.
Joel T. Steyer, Richard B. Todd
openaire   +2 more sources

Branched-Chain Amino Acids

2007
The branched-chain amino acids (BCAAs) leucine, isoleucine, and valine are synthesized by bacteria, fungi, and plants, but are essential for vertebrates including humans, who must receive them from their diet. The interest to construct overproducing industrial strains therefore stems from the need to supplement the food or feed with these amino acids ...
  +4 more sources

Branched chain amino acids as activators of branched chain ketoacid dehydrogenase

Biochemical and Biophysical Research Communications, 1978
Abstract During purification of branched chain ketoacid dehydrogenase from Pseudomonas putida , large losses in enzyme activity occurred. Much of the activity was restored by the addition of a heat-treated, soluble fraction. The factor had a molecular weight less than 1000 and, of several potential effectors tested, the branched chain amino ...
C M, Roberts, J R, Sokatch
openaire   +2 more sources

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