Results 221 to 230 of about 70,347 (257)
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The Branched-Chain Amino Acid Antagonism in Chicks
The Journal of Nutrition, 1978The effects of dietary supplements of branched-chain amino acids on growth, food consumption and metabolism in chicks were investigated. When an adequate diet contained 1.20, 1.60, 2.25, 3.75, or 5.00% leucine, increasing leucine content caused reduced food consumption and weight gains, coupled with impaired efficiency of food utilization.
T K, Smith, R E, Austic
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Evolution of the biosynthesis of the branched-chain amino acids
Origins of Life and Evolution of the Biosphere, 1995The origin of the biosynthetic pathways for the branched-chain amino acids cannot be understood in terms of the backwards development of the present acetolactate pathway because it contains unstable intermediates. We propose that the first biosynthesis of the branched-chain amino acids was by the reductive carboxylation of short branched chain fatty ...
A D, Keefe, A, Lazcano, S L, Miller
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Branched Chain Amino Acids in Metabolic Disease
Current Diabetes Reports, 2018Elevations in circulating branched chain amino acids (BCAAs) have gained attention as potential contributors to the development of insulin resistance and diabetes.Epidemiological evidence strongly supports this conclusion. Suppression of BCAA catabolism in adipose and hepatic tissues appears to be the primary drivers of plasma BCAA elevations.
Zoltan, Arany, Michael, Neinast
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Branched chain amino acids—What are they good for?
Clinical Nutrition, 1982Abstract From the above consideration it is apparent that the BCAA fulfill unique physiological functions in normal man. Thus, the BCAA constitute a principal source of nitrogen repletion in muscle tissue after the ingestion of a protein meal. In addition, the BCAA and leucine in particular have been implicated in the regulation of synthesis as well ...
L S, Eriksson, J, Wharen
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Branched-Chain Amino Acids and Brain Metabolism
Neurochemical Research, 2017This review aims to provide a historical reference of branched-chain amino acid (BCAA) metabolism and provide a link between peripheral and central nervous system (CNS) metabolism of BCAAs. Leucine, isoleucine, and valine (Leu, Ile, and Val) are unlike most other essential amino acids (AA), being transaminated initially in extrahepatic tissues, and ...
Justin E, Sperringer +2 more
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Branched-chain amino acids for hepatic encephalopathy
2003Hepatic encephalopathy may be caused by a decreased plasma ratio of branched-chain amino acids (BCAA) to aromatic amino acids. Treatment with BCAA may therefore have a beneficial effect on patients with hepatic encephalopathy.To evaluate the beneficial and harmful effects of BCAA for patients with hepatic encephalopathy.We identified trials through The
B, Als-Nielsen +3 more
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[The branched-chain amino acids].
Minerva gastroenterologica e dietologica, 2006Branched-chain amino acids (BCAA: leucine, isoleucine and valine) are not just structural constituents of proteins, but have ''pharmacologic'' properties, known for several years: BCAA are catabolized mainly in muscle; can be oxidized with energy production, being nitrogen donors for other amino acids; regulate protein synthesis and degradation ...
C, Chiarla +3 more
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Branched chain amino acids in heptatic encephalopathy
The American Journal of Surgery, 2002Early theories or hepatic encephalopathy focused on ammonia-driven disruption of the Krebs cycle and cellular energy production. The "false-neurotransmitter" theory directed attention toward the interactions of amino acids, metabolism, the blood-brain barrier and neurotransmission.
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Regulation of Branched-Chain Amino Acid Catabolism ,
The Journal of Nutrition, 1994Catabolism of the branched-chain amino acids is regulated in part at the step catalyzed by the branched-chain alpha-ketoacid dehydrogenase complex. Previous work suggests both short-term and long-term control mechanisms are involved in regulation of the kinase responsible for phosphorylation and inactivation of the branched-chain alpha-ketoacid ...
R A, Harris +3 more
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The metabolic role of branched-chain amino acids
Nutrition, 200214 C] leucine entering the tissue is decarboxylated in the diaphragm and that a considerable proportion is degraded even further. The percentages of decarboxylation for isoleucine (58%) and valine (31%) also were substantial. Addition of insulin brought about a small but consistent stimulation of leucine oxidation.
Herbert R, Freund, Menachem, Hanani
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