Results 171 to 180 of about 5,030,655 (363)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Pengaruh Kesadaran Merek, Persepsi Kualitas dan Asosiasi Merek terhadap Loyalitas Merek melalui Kepuasan Konsumen sebagai Variabel Intervening pada Pengguna Im3 (Studi pada Mahasiswa S1 Universitas Diponegoro Semarang) [PDF]

open access: yes, 2017
This research is motivated by the development of the world of technology,especially mobile phones that result in intense competition among companies. IM3 alwaysstrive to provide the best service to consumers through the services they have.
Saryadi, S. (Saryadi)   +1 more
core  

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

open access: yesMolecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci   +6 more
wiley   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

ANALISIS PENGARUH KESADARAN MEREK, ASOSIASI MEREK, DAN PERSEPSI KUALITAS TERHADAP MINAT MEREFERENSIKAN SEPEDA MOTOR SUZUKI (Studi Kasus pada Mahasiswa Fakultas Ekonomi Universitas Diponegoro) [PDF]

open access: yes, 2010
According to the survey of Top Brand Index of Motor Cycle in Indonesia, Suzuki cannot occupy TOP position in 2010 in all classes of products. The principal issue in this research is how the power of brand equity which consists of brand awareness ...
MUNFARIDIN, Munfaridin, SUTOPO, Sutopo
core  

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