Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Moroccan used cars dataset: Insights into the used car market. [PDF]
Tabarnoust E, Mghari M, Zaz Y.
europepmc +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
The role of brand commitment and external information in urban consumers' organic produce choices: Evidence from Japan and China. [PDF]
Yang R, Yagi H, Fuyuki K.
europepmc +1 more source
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Microplastics identified in commercial over-the-counter lubricant eyedrops. [PDF]
Jaeger J +10 more
europepmc +1 more source
Deep Learning-Assisted Diagnostic System: Implant Brand Detection Using Improved IB-YOLOv10 in Periapical Radiographs. [PDF]
Lin YJ +11 more
europepmc +1 more source
Anthropomorphism Unveiled: A Decade of Systematic Insights in Business and Technology Trends. [PDF]
Pramesti DA +3 more
europepmc +1 more source
Quantitative Method for Analysis of Lipids by LC-HRMS and Fatty Acid Methyl Ester by GC-FID in Macauba (Acrocomia aculeata) Oils. [PDF]
Ferro EZS +3 more
europepmc +1 more source
Predicting Consumer Adoption of Luxury Products via Instagram Marketing: A Machine Learning Approach. [PDF]
Nallasivam A +4 more
europepmc +1 more source

