Results 91 to 100 of about 65,986 (255)

Prophylactic mastectomy for the prevention of breast cancer: Review of the literature

open access: yesAvicenna Journal of Medicine, 2018
The high incidence and recurrence rate of breast cancer has influenced multiple strategies such as early detection with imaging, chemoprevention and surgical interventions that serve as preventive measures for women at high risk.
Rawan K. Alaofi   +2 more
doaj   +1 more source

Comparison of suspected Lynch syndrome patients carrying BRCA and BRCA‐like variants with Lynch syndrome probands: Phenotypic characteristics and pedigree analyses

open access: yesMolecular Genetics & Genomic Medicine, 2020
Background Colorectal cancer (CRC) patients diagnosed with Lynch syndrome (LS) are recommended genetic testing. Increasing numbers of germline variants involved in homologous recombination have been identified in suspected LS patients.
Yun Xu   +4 more
doaj   +1 more source

DNA stabilization by the upregulation of estrogen signaling in BRCA gene mutation carriers

open access: yes, 2015
Zsuzsanna Suba Surgical and Molecular Tumor Pathology Centre, National Institute of Oncology, Budapest, Hungary Abstract: Currently available scientific evidence erroneously suggests that mutagenic weakness or loss of the BRCA1/2 genes may liberate the
Suba Z
core  

BRCA-ATAC and Gene expression analysis

open access: yes, 2022
ATAC and Gene expression ...
Mingda Zhu (11901296)
core   +1 more source

Health and Disease After Assisted Reproductive Technology

open access: yesFertility & Reproduction, 2019
Long-term health outcomes after ART have largely focused on offspring health and perinatal parameters. Longer-term health outcomes in female patients remain difficult to fully assess.
Cathy Allen
doaj   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

open access: yesAnimal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang   +10 more
wiley   +1 more source

Role of Olaparib in the Management of Metastatic Castration-Resistant Prostate Cancer: A Japanese Clinician’s Perspective

open access: yesCancer Management and Research, 2022
Takashi Matsumoto, Masaki Shiota, Leandro Blas, Masatoshi Eto Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, JapanCorrespondence: Masaki Shiota, Department of Urology, Graduate School of Medical Sciences, Kyushu ...
Matsumoto T, Shiota M, Blas L, Eto M
doaj  

BRCA tra presente e futuro 6-7 Dicembre 2019 Roma Aula Valdoni Pol. Umberto 1 Viale del policlinico 155 Presidenti Prof. Massimo Monti Prof. Diego Ribuffo Prof Paolo Marchetti

open access: yes, 2019
Razionale LaMedicinadiPrecisioneedinparticolarel’OncologiaPer- sonalizzata pongono al centro della cura ilPaziente . Le nuove conoscenzedibiologiaebiologiamolecolare,infatti, consentono di trattare i nostri Pazientisulle base di carat ...
massimo monti   +7 more
core  

BRCA 1 and BRCA 2 mutations in Saudi breast cancer patients (single institution).

open access: yes, 2014
10 Background: Breast cancer is the commonest malignancy among Saudi females accounting for 25% of all female cancers with a median age at diagnosis of 47 years (1,2).
Omalkhair A. M. Abulkhair
core   +1 more source

BRCA promoter methylation in sporadic versus BRCA germline mutation-related breast cancers [PDF]

open access: yes, 2017
Background: In breast cancer, BRCA promoter hypermethylation and BRCA germline mutations are said to occur together rarely, but this property has not yet been translated into a clinical test.
Cathy Beatrice Moelans   +5 more
core   +2 more sources

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