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RNA based analysis of BRCA and BRCA gene alterations
2006Alterations in BRCA1 and BRCA2 genes account for a large proportion of hereditary breast and ovarian cancers. Mutations and variants of unknown pathological significance have been identified in both genes; however, most of them have been studied only at the genomic level, and their effect on mRNA expression remains unknown.
BONATTI F +9 more
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Hereditary non-BRCA gynecological tumors.
Minerva ginecologica, 2016Early diagnosis and proper management of gynecologic malignancies represent a challenge in modern oncology. A growing interest has arisen around the gynecological manifestations of hereditary cancer syndromes. In particular, the discovery of the BRCA1 and BRCA2 genes in ovarian cancer and the mismatch repair genes (MMR) in endometrial carcinoma has ...
Vellone VG, Paudice M, Varesco L
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Methylome profiling of BRCA-positive and BRCA-negative MBCs
European Journal of Cancer, 2016RIZZOLO, PIERA +9 more
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The antitumorigenic roles of BRCA1–BARD1 in DNA repair and replication
Nature Reviews Molecular Cell Biology, 2020Madalena Tarsounas, Patrick Sung
exaly
Journal of insurance medicine (New York, N.Y.), 1997
M L, Engman, C A, Pinkham
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M L, Engman, C A, Pinkham
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BRCA1 and its toolbox for the maintenance of genome integrity
Nature Reviews Molecular Cell Biology, 2009Michael Sy Huen +2 more
exaly