Results 191 to 200 of about 50,723 (266)

Oncofetal Biology: From Fundamental Mechanisms to Emerging Therapeutic Opportunities

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oncofetal biology provides a transformative framework for understanding cancer initiation, progression, and therapeutic intervention. This review synthesizes the core molecular mechanisms connecting embryonic development and tumorigenesis from a multidisciplinary standpoint and outlines future research trajectories and clinical applications, and we aim
Yang Liu, Kaifeng Niu, Qingran Kong, Shaorong Gao   +3 more
wiley   +1 more source

Machine learning-based programmed cell death gene signature for prognosis and drug sensitivity in breast cancer. [PDF]

Oncol Lett
Wu N, Fan Z.
europepmc   +1 more source

The Tumor Immune Microenvironment in Endometrial Cancer: Composition, Molecular Subtypes, and Therapeutic Implications

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Endometrial cancer (EC), a major gynecologic malignancy and a representative “cold tumor”, exhibits a tumor immune microenvironment (TIME) influenced by a broad range of cellular and molecular elements, immunosuppressive signals, and pathways of immune evasion.
Jingxuan Ye, Yashi Shi, Alexander Mustea, Xiaodan Mao, Pengming Sun   +4 more
wiley   +1 more source

TMEM70 drives breast cancer progression via mitochondrial oxidative phosphorylation and microenvironment remodeling. [PDF]

Cancer Cell Int
Li B, Hong Z, Lin R, Pan J, Xu H, Fang C, Zhang B, Wang K, Lau LY, Dong C, Chen Y.   +10 more
europepmc   +1 more source

Navigating Hope and Illness Cognition in Advanced Ovarian Cancer Patients: A CSM‐Based Phenomenological Study

Psycho-Oncology, Volume 35, Issue 6, June 2026.
ABSTRACT Background Advanced ovarian cancer patients face profound psychosocial challenges in maintaining hope amidst terminal illness and treatment uncertainty. Understanding mechanisms supporting adaptive hope could inform psychosocial interventions.
Yun Long, Chunchang Zhong, Cuili Wen, Fang He, Yufen Wang, Cairong Wang, Hui Xia, Yunhuang Shi, Ping Jin   +8 more
wiley   +1 more source

A comparative study of molecular characteristics of pathogenic and uncertain significance variants of BRCA1/2 in Chinese breast cancer patients. [PDF]

BMC Res Notes
Guan J, Hu J, Lin S, Chen C, Luo Y, Zhou W.   +5 more
europepmc   +1 more source

On why cancer cells require a great amount of glucose

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract The traditional thinking has been that cancer cells require a great amount of glucose to support their rapid growth, but the reality may be different. We have previously demonstrated that all cancer cells in The Cancer Genome Atlas harbor persistent Fenton reactions in their cytosol, which generate OH− ${\text{OH}}^{-}$ and ultimately kill the
Xuechen Mu, Aoran Liu, Rui Shi, Long Xu, Zhenyu Huang, Ye Zhang, Ying Xu   +6 more
wiley   +1 more source

Pathological features of BRCA-mutated breast cancer in Shenzhen, China: a single-center study. [PDF]

PeerJ
Guan J, Lin S, Liu Y, Zhou W.
europepmc   +1 more source

Single‐Cell Analysis Identifies LYPD6B as a Tumor‐Intrinsic Candidate Associated With Immunotherapy Nonresponse in Breast Cancer

Thoracic Cancer, Volume 17, Issue 11, June 2026.
LYPD6B is a tumor‐intrinsic mediator of immune evasion and resistance to PD‐(L)1 therapy in breast cancer; targeting LYPD6B may improve immunotherapy efficacy. ABSTRACT Immune checkpoint blockade (ICB) induces durable responses in a subset of breast cancer patients, yet many show limited benefit from anti‐PD‐1/PD‐L1 therapy.
Yifei Wang, Haiwei Quan, Zhiguang Xu, Yixiang Wang, Zhibin Wang   +4 more
wiley   +1 more source

PEARL: integrative multi-omics classification and omics feature discovery via deep graph learning. [PDF]

Bioinformatics
Zhao Q, Du J, Zhou M, Wang XW, Sun Q, Chen C.   +5 more
europepmc   +1 more source