Results 181 to 190 of about 50,723 (266)

Integrin α5β1‐mediated multicellular crosstalk in the tumor microenvironment drives bladder cancer progression and reveals targetable vulnerabilities

iMetaOmics, Volume 3, Issue 2, June 2026.
Integrating multiplexed immunofluorescence, animal models, and clinical samples, our single‐cell and spatial atlas maps tumor microenvironment evolution during bladder cancer (BCa) progression. We reveal that stemness‐associated tumor cells (SDC1+), POSTN+ myofibroblastic cancer‐associated fibroblasts (mCAFs), and immunosuppressive monocytic myeloid ...
Ting Liang, Wuwu Xu, Hu Fang, Lu Fu, Dashi Deng, Chenchen Li, Lisha Liu, Dongdong Tang, Huancheng Yang, Fang Liu, Xing Xiong, Guangzhi Li, Song Wu, Tao Tao   +13 more
wiley   +1 more source

F2R and MXRA5: the metabolic obesity-derived biomarkers for immunosuppression and poor survival in triple-negative breast cancer. [PDF]

Discov Oncol
Li X, Wang Z, Huo X, Luo Y.
europepmc   +1 more source

Immune Evasion in Ovarian Cancer Peritoneal Metastasis: Mechanisms and Biomarker‐Guided Therapeutic Matching

Journal of Cellular Physiology, Volume 241, Issue 6, June 2026.
This graphical abstract summarizes the major immune‐evasion mechanisms that limit immunotherapy efficacy in ovarian cancer peritoneal metastasis. Peritoneal dissemination is shaped by impaired antigen visibility, coordinated immune‐evasion modules within ascites and multicellular spheroids, checkpoint‐driven T‐cell exhaustion, suppressive tumor ...
Xiaodong Wang, Junjie Wang, Di Xiong, Songli Cui, Qianqian Wang, Yiping Huang, Gouping Ding, Yixuan Tang, Yeqian Feng   +8 more
wiley   +1 more source

Multi-Omics Characterization of ABHD12 Across Pan-Cancer and Validation of Its Role in Promoting Proliferation and Metastasis in Breast Cancer. [PDF]

Breast Cancer (Dove Med Press)
Zhao J, Gou Y, Wang Y, Li Y, Ma H, Xing Y, Peng H, Guo C.   +7 more
europepmc   +1 more source

Digital genetic counseling services for cascade cardiogenetic testing

Journal of Genetic Counseling, Volume 35, Issue 3, June 2026.
Abstract Digital interventions are potentially promising to improve accessibility and efficiency of genetic counseling services. However, current literature on user perspectives toward digital tools for cascade testing is limited. Therefore, this focus‐group study aimed to gain insights into the attitude and perspectives of probands, at‐risk relatives (
Marlies N. van Lingen, Sietske A. L. van Till, Noor A. A. Giesbertz, Tessa C. Beinema, Margreet G. E. M. Ausems, Randy Klaassen, Martina C. Cornel, Lieke M. van den Heuvel, J. Peter van Tintelen   +8 more
wiley   +1 more source

Editorial: Molecular studies and therapeutic approaches on BRCA-associated cancers. [PDF]

Front Mol Biosci
Bhat A, Wang X, Stephen P.
europepmc   +1 more source

Providing space in genetic counseling: Reflexive thematic analysis of long and short sessions across clinical specialties

Journal of Genetic Counseling, Volume 35, Issue 3, June 2026.
Abstract The duration of genetic counseling (GC) sessions can vary significantly. However, which factors contribute to sessions being abbreviated or extended and how that affects quality of care has not been well studied. This study explored variability in long versus short GC patient care time, defined as time spent in the session with the patient ...
Emily Glanton, Deborah Cragun, Heather Zierhut   +2 more
wiley   +1 more source

TGBWDriver: A Cancer Driver Gene Identification Method Based on GraphSAGE and Bidirectional Weighted Feature Aggregation. [PDF]

Int J Mol Sci
Chen J, Ren Y, Wang H, Zhan C, Zhang Y.
europepmc   +1 more source

BRCA1/2 Reversion Mutations and Cancer Therapy Resistance. [PDF]

Biology (Basel)
Qi W, Yang G, Zhang Y, Han L, Mayo KH, Zeng X, Mo J.   +6 more
europepmc   +1 more source