Results 111 to 120 of about 177,994 (348)
Exploration, EarlyView.The role of cuproptosis in HBV‐ALF was explored via bioinformatics and liver biopsy tissues. There are some crosstalks among cuproptosis, immune infiltration, and ferroptosis (The figure was created by Bio Render). ABSTRACT Hepatitis B virus (HBV) infection poses a significant challenge to global health, particularly in developing countries such as ...
Jingwen Deng +10 more
wiley +1 more source
Efficacy of Next-Generation Sequencing in Identifying Genetic Markers for Prostate Cancer Risk
Journal of Pharmacy and Bioallied SciencesBackground: Prostate cancer is one of the most prevalent cancers among men worldwide. The identification of genetic markers that contribute to the risk of prostate cancer can significantly enhance early diagnosis and personalized treatment strategies ...
Fahad H. Alaithan +2 more
doaj +1 more source
BRCA1 alternative splicing in breast tumorogenesis [PDF]
Introduction: Alternative splicing helps transcription process to produce many proteins from single gene and has important roles on tumorogenesis. The BRCA1 gene has almost 11 alternate spliced variants which have been mentioned as susceptibility ...
اخوان, هما +6 more
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Supplementary Figure S2 from DNA Damage–Induced BARD1 Phosphorylation Is Critical for the Inhibition of Messenger RNA Processing by BRCA1/BARD1 Complex [PDF]
, 2023 Ho-Shik Kim +6 more
openalex +1 more source
International Journal of Cancer, EarlyView.Abstract Genetic tumor risk syndromes (genturis) contribute substantially to the overall cancer burden and provide opportunities for early detection, prevention, and individualized treatment. Yet, many affected individuals remain undiagnosed due to restrictive testing criteria and challenges in variant interpretation.
Mayra Sauer +11 more
wiley +1 more source
Supplementary Figure S1 from Identification of Domains of BRCA1 Critical for the Ubiquitin-Dependent Inhibition of Centrosome Function [PDF]
, 2023 Satish Sankaran +3 more
openalex +1 more source
USP3 controls BRCA1 “foci” [PDF]
Cell Cycle, 2013 BRCA1, which is mutated in the familial forms of breast and ovarian cancer, plays important roles in genome stability through its participation in DNA damage response (DDR) following double-stranded breaks (DSBs). BRCA1 activates the checkpoint pathway to retard cell cycle progression and stimulates repair of the DSBs (reviewed in ref. 1).
openaire +2 more sources
International Journal of Cancer, EarlyView.Basal‐like breast cancer (BLBC) is aggressive and often exhibits inherent or acquired resistance to radiotherapy (RT), a primary treatment option. RT resistance is underpinned by molecular alterations, many of which are poorly understood. Here, RT‐induced transcriptomic changes were analyzed using bulk and spatial sequencing in a BLBC mouse model and ...
Garyfallia Pantelaiou‐Prokaki +12 more
wiley +1 more source
International Journal of General MedicineYu Luo,1,2 Ru Pan,1,2 Hui Rao,2,3 Xing Chen,4 Haikun Yang1,2 1Department of Gynaecology, Meizhou People’s Hospital, Meizhou Academy of Medical Sciences, Meizhou, People’s Republic of China; 2Meizhou Municipal Engineering and Technology Research Center ...
Luo Y, Pan R, Rao H, Chen X, Yang H
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